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[The role of resveratrol in the regulation of cell metabolism--a review].

Abstract

Moderate wine drinking is associated with reduced risk of cardiovascular, cerebrovascular and peripheral vascular disease, and reduced risk of cancer. This phenomenon is called the "French paradox", since it was observed for the first time in France--a country famous for its wine production. In the literature, the cardioprotective effect of wine is very well described and attributed mainly to contained therein resveratrol. Recently, it has been demonstrated that resveratrol extends the lifespan of yeast through activation of the SirT1 longevity gene, which is also responsible for the longevity caused by caloric restriction. Furthermore, resveratrol exhibits high biological activity, affecting cell structures and contributing to their protection. This paper summarizes the available reports on functional and molecular aspects of resveratrol, wines and grapes as a result of the activation of longevity genes.

Authors+Show Affiliations

Dział Żywienia Zwierząt i Paszoznawstwa, Instytut Zootechniki PIB, Balice.Dział Żywienia Zwierząt i Paszoznawstwa, Instytut Zootechniki PIB, Balice.Dział Genomiki i Biologii Molekularnej Zwierząt, Instytut Zootechniki PIB, Balice.Dział Genomiki i Biologii Molekularnej Zwierząt, Instytut Zootechniki PIB, Balice.Instytut Nauk o Zwierzętach, Uniwersytet Rolniczy w Krakowie.

Pub Type(s)

Journal Article
Review

Language

pol

PubMed ID

26943309

Citation

Pieszka, Marek, et al. "[The Role of Resveratrol in the Regulation of Cell Metabolism--a Review]." Postepy Higieny I Medycyny Doswiadczalnej (Online), vol. 70, 2016, pp. 117-23.
Pieszka M, Szczurek P, Ropka-Molik K, et al. [The role of resveratrol in the regulation of cell metabolism--a review]. Postepy Hig Med Dosw (Online). 2016;70:117-23.
Pieszka, M., Szczurek, P., Ropka-Molik, K., Oczkowicz, M., & Pieszka, M. (2016). [The role of resveratrol in the regulation of cell metabolism--a review]. Postepy Higieny I Medycyny Doswiadczalnej (Online), 70, pp. 117-23. doi:10.5604/17322693.1195844.
Pieszka M, et al. [The Role of Resveratrol in the Regulation of Cell Metabolism--a Review]. Postepy Hig Med Dosw (Online). 2016 Feb 25;70:117-23. PubMed PMID: 26943309.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The role of resveratrol in the regulation of cell metabolism--a review]. AU - Pieszka,Marek, AU - Szczurek,Paulina, AU - Ropka-Molik,Katarzyna, AU - Oczkowicz,Maria, AU - Pieszka,Magdalena, Y1 - 2016/02/25/ PY - 2016/3/5/entrez PY - 2016/3/5/pubmed PY - 2016/6/9/medline SP - 117 EP - 23 JF - Postepy higieny i medycyny doswiadczalnej (Online) JO - Postepy Hig Med Dosw (Online) VL - 70 N2 - Moderate wine drinking is associated with reduced risk of cardiovascular, cerebrovascular and peripheral vascular disease, and reduced risk of cancer. This phenomenon is called the "French paradox", since it was observed for the first time in France--a country famous for its wine production. In the literature, the cardioprotective effect of wine is very well described and attributed mainly to contained therein resveratrol. Recently, it has been demonstrated that resveratrol extends the lifespan of yeast through activation of the SirT1 longevity gene, which is also responsible for the longevity caused by caloric restriction. Furthermore, resveratrol exhibits high biological activity, affecting cell structures and contributing to their protection. This paper summarizes the available reports on functional and molecular aspects of resveratrol, wines and grapes as a result of the activation of longevity genes. SN - 1732-2693 UR - https://www.unboundmedicine.com/medline/citation/26943309/[The_role_of_resveratrol_in_the_regulation_of_cell_metabolism__a_review]_ L2 - http://www.phmd.pl/fulltxt.php?ICID=1195844 DB - PRIME DP - Unbound Medicine ER -