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[Clinical efficacy of moxibustion as supplement on rheumatoid arthritis and the exploration on its mechanism].
Zhongguo Zhen Jiu 2016; 36(1):17-20ZZ

Abstract

OBJECTIVE

To explore the clinical efficacy of moxibustion on rheumatoid arthritis (RA) in the patients and the impacts on the inflammatory indices.

METHODS

Forty RA patients were randomized into an observation group and a control group, 20 cases in each one. In the control group, diclofenac sodium sustained release tablets were used, 0.3 g each time, twice a day; methotrexate tablets were used, 10 mg each time, once a week; folic acid was used, 5 mg each time, once a week. In the observation group, on the basis of the treatment as the control group, moxibustion was added specially on the swelling and painful joints, once a day, 15-20 min each time till: the local skin turned slightly red. The treatment was given once a day, at the interval of 1 day after every 6 treatments. In the two groups, the efficacy was observed after 30-day treatment. Before and after treatment, the rheumatoid factor (RF), high sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), disease activity score-28 (DAS-28) and the score of joint symptom and physical signs were observed.

RESULTS

Compared with those before treatment, the levels of RF, hs-CRP, ESR, DAS-28 and the symptom scale score were all reduced in the RA patients of the two groups after treatment (all P < 0.05). Compared with the control group, the levels of RF, hs-CRP, ESR, DAS-28 and the symptom scale score in the observation group were improved much apparently (all P < 0.05). The total effective rate was 85.0% (17/20) in the observation group and was 80.0% (16/20) in the control group. The total effective rate in the observation group was apparently better than that in the control group (P < 0.05).

CONCLUSION

Moxibustion as supplement relieves the joint symptoms, reduces the inflammatory reactive indices and improves the clinical efficacy in the RA patients.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

26946727

Citation

Hongwu, Yu, et al. "[Clinical Efficacy of Moxibustion as Supplement On Rheumatoid Arthritis and the Exploration On Its Mechanism]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 36, no. 1, 2016, pp. 17-20.
Hongwu Y, Yan Z, Yuzhen P, et al. [Clinical efficacy of moxibustion as supplement on rheumatoid arthritis and the exploration on its mechanism]. Zhongguo Zhen Jiu. 2016;36(1):17-20.
Hongwu, Y., Yan, Z., Yuzhen, P., Jia, Y., Bingkun, W., Xue, H., & Yunyan, C. (2016). [Clinical efficacy of moxibustion as supplement on rheumatoid arthritis and the exploration on its mechanism]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 36(1), pp. 17-20.
Hongwu Y, et al. [Clinical Efficacy of Moxibustion as Supplement On Rheumatoid Arthritis and the Exploration On Its Mechanism]. Zhongguo Zhen Jiu. 2016;36(1):17-20. PubMed PMID: 26946727.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical efficacy of moxibustion as supplement on rheumatoid arthritis and the exploration on its mechanism]. AU - Hongwu,Yu, AU - Yan,Zhu, AU - Yuzhen,Pan, AU - Jia,Yang, AU - Bingkun,Wu, AU - Xue,Hu, AU - Yunyan,Cao, PY - 2016/3/8/entrez PY - 2016/3/8/pubmed PY - 2016/3/25/medline SP - 17 EP - 20 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 36 IS - 1 N2 - OBJECTIVE: To explore the clinical efficacy of moxibustion on rheumatoid arthritis (RA) in the patients and the impacts on the inflammatory indices. METHODS: Forty RA patients were randomized into an observation group and a control group, 20 cases in each one. In the control group, diclofenac sodium sustained release tablets were used, 0.3 g each time, twice a day; methotrexate tablets were used, 10 mg each time, once a week; folic acid was used, 5 mg each time, once a week. In the observation group, on the basis of the treatment as the control group, moxibustion was added specially on the swelling and painful joints, once a day, 15-20 min each time till: the local skin turned slightly red. The treatment was given once a day, at the interval of 1 day after every 6 treatments. In the two groups, the efficacy was observed after 30-day treatment. Before and after treatment, the rheumatoid factor (RF), high sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), disease activity score-28 (DAS-28) and the score of joint symptom and physical signs were observed. RESULTS: Compared with those before treatment, the levels of RF, hs-CRP, ESR, DAS-28 and the symptom scale score were all reduced in the RA patients of the two groups after treatment (all P < 0.05). Compared with the control group, the levels of RF, hs-CRP, ESR, DAS-28 and the symptom scale score in the observation group were improved much apparently (all P < 0.05). The total effective rate was 85.0% (17/20) in the observation group and was 80.0% (16/20) in the control group. The total effective rate in the observation group was apparently better than that in the control group (P < 0.05). CONCLUSION: Moxibustion as supplement relieves the joint symptoms, reduces the inflammatory reactive indices and improves the clinical efficacy in the RA patients. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/26946727/[Clinical_efficacy_of_moxibustion_as_supplement_on_rheumatoid_arthritis_and_the_exploration_on_its_mechanism]_ L2 - http://www.diseaseinfosearch.org/result/592 DB - PRIME DP - Unbound Medicine ER -