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Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere.
J Virol. 2016 05 15; 90(10):4864-4875.JV

Abstract

Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern. In this review, we discuss the history and epidemiology of ZIKV infection, recent outbreaks in Oceania and the emergence of ZIKV in the Western Hemisphere, newly ascribed complications of ZIKV infection, including Guillain-Barré syndrome and microcephaly, potential interactions between ZIKV and dengue virus, and the prospects for the development of antiviral agents and vaccines.

Authors+Show Affiliations

Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA helen.lazear@med.unc.edu diamond@borcim.wustl.edu.Departments of Medicine, Molecular Microbiology, Pathology, and Immunology and The Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, Missouri, USA helen.lazear@med.unc.edu diamond@borcim.wustl.edu.

Pub Type(s)

Journal Article
Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26962217

Citation

Lazear, Helen M., and Michael S. Diamond. "Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere." Journal of Virology, vol. 90, no. 10, 2016, pp. 4864-4875.
Lazear HM, Diamond MS. Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere. J Virol. 2016;90(10):4864-4875.
Lazear, H. M., & Diamond, M. S. (2016). Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere. Journal of Virology, 90(10), 4864-4875. https://doi.org/10.1128/JVI.00252-16
Lazear HM, Diamond MS. Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere. J Virol. 2016 05 15;90(10):4864-4875. PubMed PMID: 26962217.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere. AU - Lazear,Helen M, AU - Diamond,Michael S, Y1 - 2016/04/29/ PY - 2016/3/11/entrez PY - 2016/3/11/pubmed PY - 2017/4/27/medline SP - 4864 EP - 4875 JF - Journal of virology JO - J. Virol. VL - 90 IS - 10 N2 - Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern. In this review, we discuss the history and epidemiology of ZIKV infection, recent outbreaks in Oceania and the emergence of ZIKV in the Western Hemisphere, newly ascribed complications of ZIKV infection, including Guillain-Barré syndrome and microcephaly, potential interactions between ZIKV and dengue virus, and the prospects for the development of antiviral agents and vaccines. SN - 1098-5514 UR - https://www.unboundmedicine.com/medline/citation/26962217/Zika_Virus:_New_Clinical_Syndromes_and_Its_Emergence_in_the_Western_Hemisphere_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26962217/ DB - PRIME DP - Unbound Medicine ER -