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[Correlation Analysis Between Common Peaks of Angelica sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil].
Zhong Yao Cai. 2015 Aug; 38(8):1595-9.ZY

Abstract

OBJECTIVE

To investigate the correlation between common peaks of Angelica sinensis HPLC fingerprint and mineral elements in its growing soil.

METHODS

The fingerprints of 120 batches of Angelica sinensis from 12 habitats were determined by HPLC. The contents of Pb, As, Cr, Sb, Hg, Cu, Cd, Ni, Zn, Mg, Mn, Ca, Fe, Na and K in corresponding soil were determined by ICP-MS and AAS. Bivariate and multiple linear regression were used to analyze the correlation.

RESULTS

There were significant (P < 0. 01 or P < 0.05) positive and negative correlation between many common peaks in HPLC fingerprint of Angelica sinensis and mineral elements in its growing soil. The contribution of mineral elements in soil on peak 1 were Zn > K > Sb > Fe > Na; on peak 6 (3-butylphthalide) were Mn > Mg > Ca; on peak 7 were Cr > Zn; on peak 8 were Mn > Na; on peak 11 were As > K > Fe > Cd; on peak 12 were Zn > Mn > K; on peak 13 (Z-butylidenephthalide) were Mn > Zn > Cd; on peak 15 were Zn > K; on peak 16 were Fe > Ni; on peak 17 were Zn > Mn > Ni > Fe > K; on peak 18 were Zn > Na; peaks 2,3 (ferulic acid), 4 and 14 (Z-ligustilide) was mainly affected by As, Zn, Sb and Cu, respectively.

CONCLUSION

The relationship between HPLC fingerprint peak of Angelica sinensis and mineral elements in its growing soil shows complexity, multiplicity and interactivity, which should be selectively examined during manuring micronutrient fertilizer and Angelica sinensis cultivation.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

26983227

Citation

Ding, Jun-xia, et al. "[Correlation Analysis Between Common Peaks of Angelica Sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 38, no. 8, 2015, pp. 1595-9.
Ding JX, Gu ZR, Wang YL, et al. [Correlation Analysis Between Common Peaks of Angelica sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil]. Zhong Yao Cai. 2015;38(8):1595-9.
Ding, J. X., Gu, Z. R., Wang, Y. L., Zhang, Y. Y., Wang, Y. P., & Sun, Y. J. (2015). [Correlation Analysis Between Common Peaks of Angelica sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 38(8), 1595-9.
Ding JX, et al. [Correlation Analysis Between Common Peaks of Angelica Sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil]. Zhong Yao Cai. 2015;38(8):1595-9. PubMed PMID: 26983227.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Correlation Analysis Between Common Peaks of Angelica sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil]. AU - Ding,Jun-xia, AU - Gu,Zhi-rong, AU - Wang,Ya-li, AU - Zhang,Ya-ya, AU - Wang,Yao-peng, AU - Sun,Yu-jing, PY - 2016/3/18/entrez PY - 2016/3/18/pubmed PY - 2016/5/26/medline SP - 1595 EP - 9 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 38 IS - 8 N2 - OBJECTIVE: To investigate the correlation between common peaks of Angelica sinensis HPLC fingerprint and mineral elements in its growing soil. METHODS: The fingerprints of 120 batches of Angelica sinensis from 12 habitats were determined by HPLC. The contents of Pb, As, Cr, Sb, Hg, Cu, Cd, Ni, Zn, Mg, Mn, Ca, Fe, Na and K in corresponding soil were determined by ICP-MS and AAS. Bivariate and multiple linear regression were used to analyze the correlation. RESULTS: There were significant (P < 0. 01 or P < 0.05) positive and negative correlation between many common peaks in HPLC fingerprint of Angelica sinensis and mineral elements in its growing soil. The contribution of mineral elements in soil on peak 1 were Zn > K > Sb > Fe > Na; on peak 6 (3-butylphthalide) were Mn > Mg > Ca; on peak 7 were Cr > Zn; on peak 8 were Mn > Na; on peak 11 were As > K > Fe > Cd; on peak 12 were Zn > Mn > K; on peak 13 (Z-butylidenephthalide) were Mn > Zn > Cd; on peak 15 were Zn > K; on peak 16 were Fe > Ni; on peak 17 were Zn > Mn > Ni > Fe > K; on peak 18 were Zn > Na; peaks 2,3 (ferulic acid), 4 and 14 (Z-ligustilide) was mainly affected by As, Zn, Sb and Cu, respectively. CONCLUSION: The relationship between HPLC fingerprint peak of Angelica sinensis and mineral elements in its growing soil shows complexity, multiplicity and interactivity, which should be selectively examined during manuring micronutrient fertilizer and Angelica sinensis cultivation. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/26983227/[Correlation_Analysis_Between_Common_Peaks_of_Angelica_sinensis_HPLC_Fingerprint_and_Mineral_Elements_in_Its_Growing_Soil]_ L2 - https://antibodies.cancer.gov/detail/CPTC-CTLA4-1 DB - PRIME DP - Unbound Medicine ER -