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[Airway responsiveness measured by body plethysmograph connecting a circuit of an inhalation system of serially concentrated bronchoconstrictant].
Nihon Kyobu Shikkan Gakkai Zasshi. 1989 Dec; 27(12):1460-6.NK

Abstract

We developed a new methodology to examine the bronchial response to the bronchoconstrictants, acetylcholine and methacholine. An inhalation device was connected to the body plethysmograph circuit so that a minute inhalation of serially concentrated bronchoconstrictant could be quickly switched to the circuit of the measurement of the airway resistance. The following were calculated: airway responsiveness in terms of sensitivity, provocative dose to increase the airway resistance up to 35% from the baseline. PC35 or PD35 and the reactivity, the slope of the declining specific airway conductance and %delta SGaw. The airway responsiveness was examined in asthmatics, COPD outgrew -childhood asthma patients and normal subjects. These three groups were categorised differently from each other in both sensitivity and reactivity.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

2698420

Citation

Uno-Komase, Y, et al. "[Airway Responsiveness Measured By Body Plethysmograph Connecting a Circuit of an Inhalation System of Serially Concentrated Bronchoconstrictant]." Nihon Kyobu Shikkan Gakkai Zasshi, vol. 27, no. 12, 1989, pp. 1460-6.
Uno-Komase Y, Murakami S, Ito T, et al. [Airway responsiveness measured by body plethysmograph connecting a circuit of an inhalation system of serially concentrated bronchoconstrictant]. Nihon Kyobu Shikkan Gakkai Zasshi. 1989;27(12):1460-6.
Uno-Komase, Y., Murakami, S., Ito, T., Kudo, K., Sano, Y., & Kabe, J. (1989). [Airway responsiveness measured by body plethysmograph connecting a circuit of an inhalation system of serially concentrated bronchoconstrictant]. Nihon Kyobu Shikkan Gakkai Zasshi, 27(12), 1460-6.
Uno-Komase Y, et al. [Airway Responsiveness Measured By Body Plethysmograph Connecting a Circuit of an Inhalation System of Serially Concentrated Bronchoconstrictant]. Nihon Kyobu Shikkan Gakkai Zasshi. 1989;27(12):1460-6. PubMed PMID: 2698420.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Airway responsiveness measured by body plethysmograph connecting a circuit of an inhalation system of serially concentrated bronchoconstrictant]. AU - Uno-Komase,Y, AU - Murakami,S, AU - Ito,T, AU - Kudo,K, AU - Sano,Y, AU - Kabe,J, PY - 1989/12/1/pubmed PY - 1989/12/1/medline PY - 1989/12/1/entrez SP - 1460 EP - 6 JF - Nihon Kyobu Shikkan Gakkai zasshi JO - Nihon Kyobu Shikkan Gakkai Zasshi VL - 27 IS - 12 N2 - We developed a new methodology to examine the bronchial response to the bronchoconstrictants, acetylcholine and methacholine. An inhalation device was connected to the body plethysmograph circuit so that a minute inhalation of serially concentrated bronchoconstrictant could be quickly switched to the circuit of the measurement of the airway resistance. The following were calculated: airway responsiveness in terms of sensitivity, provocative dose to increase the airway resistance up to 35% from the baseline. PC35 or PD35 and the reactivity, the slope of the declining specific airway conductance and %delta SGaw. The airway responsiveness was examined in asthmatics, COPD outgrew -childhood asthma patients and normal subjects. These three groups were categorised differently from each other in both sensitivity and reactivity. SN - 0301-1542 UR - https://www.unboundmedicine.com/medline/citation/2698420/[Airway_responsiveness_measured_by_body_plethysmograph_connecting_a_circuit_of_an_inhalation_system_of_serially_concentrated_bronchoconstrictant]_ DB - PRIME DP - Unbound Medicine ER -