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[Role of SD-OCT in the diagnosis and prognosis of macular hypoplasia in nystagmus patients].
J Fr Ophtalmol. 2016 Mar; 39(3):272-6.JF

Abstract

PURPOSE

To investigate whether spectral domain optical coherence tomography (SD-OCT) is helpful for the diagnosis and prognosis of foveal hypoplasia in patients with overt nystagmus.

METHODS

A retrospective cross-sectional study was conducted in 48 patients with overt nystagmus. All patients underwent a complete ophthalmic examination including best corrected visual acuity, biomicroscopic and fundus examinations. Spectral domain optical coherence tomography was performed using 3D OCT-2000 FA PLUS Topcon, Tokyo, Japan, for the diagnosis and grading of foveal hypoplasia, using the Thomas classification, and its possible correlation with visual acuity.

RESULTS

Foveal hypoplasia was diagnosed in 6 patients (12.5%). The mean age of the patients was 13.2 years (10-18 years). Mean visual acuity was 1.53/10 (0.87 LogMAR). Foveal hypoplasia was associated with aniridia in 2 patients, albinism in 3 patients and keratoconus in 1 case. On SD-OCT, foveal hypoplasia was grade 4 in 4 patients and grade 3 in 2 patients. Mean visual acuity was 2.55/10 in patients with grade 3 foveal hypoplasia and 1.22/10 in patients with grade 4 foveal hypoplasia, and the difference in visual acuity between the two groups was statistically significant (P<0.001).

CONCLUSION

SD-OCT plays a double role in the diagnosis and prognosis of foveal hypoplasia in patients with nystagmus.

Authors+Show Affiliations

Service B, faculté de médecine de Tunis, institut Hédi Rais d'ophtalmologie de Tunis, université Tunis El Manar, boulevard du 9-Avril-1938, Tunis, Tunisie.Service B, faculté de médecine de Tunis, institut Hédi Rais d'ophtalmologie de Tunis, université Tunis El Manar, boulevard du 9-Avril-1938, Tunis, Tunisie. Electronic address: mejdabouladi@yahoo.fr.Service B, faculté de médecine de Tunis, institut Hédi Rais d'ophtalmologie de Tunis, université Tunis El Manar, boulevard du 9-Avril-1938, Tunis, Tunisie.Service B, faculté de médecine de Tunis, institut Hédi Rais d'ophtalmologie de Tunis, université Tunis El Manar, boulevard du 9-Avril-1938, Tunis, Tunisie.Service B, faculté de médecine de Tunis, institut Hédi Rais d'ophtalmologie de Tunis, université Tunis El Manar, boulevard du 9-Avril-1938, Tunis, Tunisie.

Pub Type(s)

Journal Article

Language

fre

PubMed ID

26995079

Citation

Bouraoui, R, et al. "[Role of SD-OCT in the Diagnosis and Prognosis of Macular Hypoplasia in Nystagmus Patients]." Journal Francais D'ophtalmologie, vol. 39, no. 3, 2016, pp. 272-6.
Bouraoui R, Bouladi M, Nefaa F, et al. [Role of SD-OCT in the diagnosis and prognosis of macular hypoplasia in nystagmus patients]. J Fr Ophtalmol. 2016;39(3):272-6.
Bouraoui, R., Bouladi, M., Nefaa, F., Limaiem, R., & El Matri, L. (2016). [Role of SD-OCT in the diagnosis and prognosis of macular hypoplasia in nystagmus patients]. Journal Francais D'ophtalmologie, 39(3), 272-6. https://doi.org/10.1016/j.jfo.2015.10.007
Bouraoui R, et al. [Role of SD-OCT in the Diagnosis and Prognosis of Macular Hypoplasia in Nystagmus Patients]. J Fr Ophtalmol. 2016;39(3):272-6. PubMed PMID: 26995079.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Role of SD-OCT in the diagnosis and prognosis of macular hypoplasia in nystagmus patients]. AU - Bouraoui,R, AU - Bouladi,M, AU - Nefaa,F, AU - Limaiem,R, AU - El Matri,L, Y1 - 2016/03/16/ PY - 2015/08/21/received PY - 2015/10/11/accepted PY - 2016/3/21/entrez PY - 2016/3/21/pubmed PY - 2017/1/31/medline KW - Acuité visuelle KW - Foveal hypoplasia KW - Hypoplasie fovéolaire KW - Nystagmus KW - OCT spectral domain KW - Spectral domain OCT KW - Visual acuity SP - 272 EP - 6 JF - Journal francais d'ophtalmologie JO - J Fr Ophtalmol VL - 39 IS - 3 N2 - PURPOSE: To investigate whether spectral domain optical coherence tomography (SD-OCT) is helpful for the diagnosis and prognosis of foveal hypoplasia in patients with overt nystagmus. METHODS: A retrospective cross-sectional study was conducted in 48 patients with overt nystagmus. All patients underwent a complete ophthalmic examination including best corrected visual acuity, biomicroscopic and fundus examinations. Spectral domain optical coherence tomography was performed using 3D OCT-2000 FA PLUS Topcon, Tokyo, Japan, for the diagnosis and grading of foveal hypoplasia, using the Thomas classification, and its possible correlation with visual acuity. RESULTS: Foveal hypoplasia was diagnosed in 6 patients (12.5%). The mean age of the patients was 13.2 years (10-18 years). Mean visual acuity was 1.53/10 (0.87 LogMAR). Foveal hypoplasia was associated with aniridia in 2 patients, albinism in 3 patients and keratoconus in 1 case. On SD-OCT, foveal hypoplasia was grade 4 in 4 patients and grade 3 in 2 patients. Mean visual acuity was 2.55/10 in patients with grade 3 foveal hypoplasia and 1.22/10 in patients with grade 4 foveal hypoplasia, and the difference in visual acuity between the two groups was statistically significant (P<0.001). CONCLUSION: SD-OCT plays a double role in the diagnosis and prognosis of foveal hypoplasia in patients with nystagmus. SN - 1773-0597 UR - https://www.unboundmedicine.com/medline/citation/26995079/[Role_of_SD_OCT_in_the_diagnosis_and_prognosis_of_macular_hypoplasia_in_nystagmus_patients]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(16)00053-X DB - PRIME DP - Unbound Medicine ER -