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Antioxidant compounds from the stem bark of Garcinia atroviridis.
J Asian Nat Prod Res. 2016 Aug; 18(8):804-11.JA

Abstract

A new xanthone, namely garcinexanthone G (1), along with eight known compounds, stigmasta-5,22-dien-3β-ol (2), stigmasta-5,22-dien-3-O-β-glucopyranoside (3), 3β-acetoxy-11α,12α-epoxyoleanan-28,13β-olide (4), 2,6-dimethoxy-p-benzoquinone (5), 1,3,5-trihydroxy-2-methoxyxanthone (6), 1,3,7-trihydroxyxanthone (7), kaempferol (8) and quercetin (9), were isolated from the stem bark of Garcinia atroviridis. Their structures were elucidated based on spectroscopic methods including nuclear magnetic resonance (NMR-1D and 2D), UV, IR, and mass spectrometry. All the isolated compounds were evaluated for their antioxidant properties based on the DPPH radical scavenging activities. Results showed that 1,3,7-trihydroxyxanthone and quercetin showed significant antioxidant activities with EC50 values of 16.20 and 12.68 μg/ml, respectively, as compared to the control, ascorbic acid (7.4 μg/ml).

Authors+Show Affiliations

a School of Distance Education , Universiti Sains Malaysia , Penang , Malaysia.b School of Chemical Sciences , Universiti Sains Malaysia , Penang , Malaysia.b School of Chemical Sciences , Universiti Sains Malaysia , Penang , Malaysia.c Section of Bioengineering Technology , Universiti Kuala Lumpur (UNIKL) MICET , Kuala Lumpur , Malaysia.d Industrial Biotechnology Research Laboratory, School of Biological Sciences , Universiti Sains Malaysia , Penang , Malaysia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26999039

Citation

Tan, Wen-Nee, et al. "Antioxidant Compounds From the Stem Bark of Garcinia Atroviridis." Journal of Asian Natural Products Research, vol. 18, no. 8, 2016, pp. 804-11.
Tan WN, Khairuddean M, Wong KC, et al. Antioxidant compounds from the stem bark of Garcinia atroviridis. J Asian Nat Prod Res. 2016;18(8):804-11.
Tan, W. N., Khairuddean, M., Wong, K. C., Tong, W. Y., & Ibrahim, D. (2016). Antioxidant compounds from the stem bark of Garcinia atroviridis. Journal of Asian Natural Products Research, 18(8), 804-11. https://doi.org/10.1080/10286020.2016.1160071
Tan WN, et al. Antioxidant Compounds From the Stem Bark of Garcinia Atroviridis. J Asian Nat Prod Res. 2016;18(8):804-11. PubMed PMID: 26999039.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant compounds from the stem bark of Garcinia atroviridis. AU - Tan,Wen-Nee, AU - Khairuddean,Melati, AU - Wong,Keng-Chong, AU - Tong,Woei-Yenn, AU - Ibrahim,Darah, Y1 - 2016/03/21/ PY - 2016/3/22/entrez PY - 2016/3/22/pubmed PY - 2017/1/4/medline KW - DPPH radical scavenging activity KW - Garcinia atroviridis KW - xanthone SP - 804 EP - 11 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 18 IS - 8 N2 - A new xanthone, namely garcinexanthone G (1), along with eight known compounds, stigmasta-5,22-dien-3β-ol (2), stigmasta-5,22-dien-3-O-β-glucopyranoside (3), 3β-acetoxy-11α,12α-epoxyoleanan-28,13β-olide (4), 2,6-dimethoxy-p-benzoquinone (5), 1,3,5-trihydroxy-2-methoxyxanthone (6), 1,3,7-trihydroxyxanthone (7), kaempferol (8) and quercetin (9), were isolated from the stem bark of Garcinia atroviridis. Their structures were elucidated based on spectroscopic methods including nuclear magnetic resonance (NMR-1D and 2D), UV, IR, and mass spectrometry. All the isolated compounds were evaluated for their antioxidant properties based on the DPPH radical scavenging activities. Results showed that 1,3,7-trihydroxyxanthone and quercetin showed significant antioxidant activities with EC50 values of 16.20 and 12.68 μg/ml, respectively, as compared to the control, ascorbic acid (7.4 μg/ml). SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/26999039/Antioxidant_compounds_from_the_stem_bark_of_Garcinia_atroviridis_ L2 - https://www.tandfonline.com/doi/full/10.1080/10286020.2016.1160071 DB - PRIME DP - Unbound Medicine ER -