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Zika virus and the current outbreak: an overview.
Neth J Med 2016; 74(3):104-9NJ

Abstract

Zika virus (ZIKV), a mosquito-borne flavivirus closely related to yellow fever virus and dengue virus, is currently causing a large outbreak in the Americas. Historically, ZIKV infection was considered a sporadic, relatively mild disease characterised by fever, maculopapular rash, conjunctivitis and often arthralgia. However, current observational studies suggest that ZIKV may cause more severe neurological sequelae such as Guillain-Barre syndrome, and birth defects, mainly microcephaly, in babies of whom the mother was infected with ZIKV during pregnancy. This article provides a clinically focussed overview of ZIKV, with emphasis on the current outbreak, clinical manifestations, diagnostic tools and caveats.

Authors+Show Affiliations

Department of Viroscience, Erasmus MC, the Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27020989

Citation

Goeijenbier, M, et al. "Zika Virus and the Current Outbreak: an Overview." The Netherlands Journal of Medicine, vol. 74, no. 3, 2016, pp. 104-9.
Goeijenbier M, Slobbe L, van der Eijk A, et al. Zika virus and the current outbreak: an overview. Neth J Med. 2016;74(3):104-9.
Goeijenbier, M., Slobbe, L., van der Eijk, A., de Mendonça Melo, M., Koopmans, M. P., & Reusken, C. B. (2016). Zika virus and the current outbreak: an overview. The Netherlands Journal of Medicine, 74(3), pp. 104-9.
Goeijenbier M, et al. Zika Virus and the Current Outbreak: an Overview. Neth J Med. 2016;74(3):104-9. PubMed PMID: 27020989.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zika virus and the current outbreak: an overview. AU - Goeijenbier,M, AU - Slobbe,L, AU - van der Eijk,A, AU - de Mendonça Melo,M, AU - Koopmans,M P G, AU - Reusken,C B E M, PY - 2016/3/30/entrez PY - 2016/3/30/pubmed PY - 2017/1/25/medline SP - 104 EP - 9 JF - The Netherlands journal of medicine JO - Neth J Med VL - 74 IS - 3 N2 - Zika virus (ZIKV), a mosquito-borne flavivirus closely related to yellow fever virus and dengue virus, is currently causing a large outbreak in the Americas. Historically, ZIKV infection was considered a sporadic, relatively mild disease characterised by fever, maculopapular rash, conjunctivitis and often arthralgia. However, current observational studies suggest that ZIKV may cause more severe neurological sequelae such as Guillain-Barre syndrome, and birth defects, mainly microcephaly, in babies of whom the mother was infected with ZIKV during pregnancy. This article provides a clinically focussed overview of ZIKV, with emphasis on the current outbreak, clinical manifestations, diagnostic tools and caveats. SN - 1872-9061 UR - https://www.unboundmedicine.com/medline/citation/27020989/Zika_virus_and_the_current_outbreak:_an_overview_ L2 - http://www.njmonline.nl/njm/getarticle.php?v=74&i=3&p=104 DB - PRIME DP - Unbound Medicine ER -