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Effects of replacing saturated fat with complex carbohydrate in diets of subjects with NIDDM.

Abstract

This study examined the safety of an isocaloric high-complex carbohydrate low-saturated fat diet (HICARB) in obese patients with non-insulin-dependent diabetes mellitus (NIDDM). Although hypocaloric diets should be recommended to these patients, many find compliance with this diet difficult; therefore, the safety of an isocaloric increase in dietary carbohydrate needs assessment. Lipoprotein cholesterol and triglyceride (TG, mg/dl) concentrations in isocaloric high-fat and HICARB diets were compared in 7 NIDDM subjects (fat 32 +/- 3%, fasting glucose 190 +/- 38 mg/dl) and 6 nondiabetic subjects (fat 33 +/- 5%). They ate a high-fat diet (43% carbohydrate; 42% fat, polyunsaturated to saturated 0.3; fiber 9 g/1000 kcal; cholesterol 550 mg/day) for 7-10 days. Control subjects (3 NIDDM, 3 nondiabetic) continued this diet for 5 wk. The 13 subjects changed to a HICARB diet (65% carbohydrate; 21% fat, polyunsaturated to saturated 1.2; fiber 18 g/1000 kcal; cholesterol 550 mg/day) for 5 wk. NIDDM subjects on the HICARB diet had decreased low-density lipoprotein cholesterol (LDL-chol) concentrations (107 vs. 82, P less than .001), but their high-density lipoprotein cholesterol (HDL-chol) concentrations, glucose, and body weight were unchanged. Changes in total plasma TG concentrations in NIDDM subjects were heterogeneous. Concentrations were either unchanged or had decreased in 5 and increased in 2 NIDDM subjects. Nondiabetic subjects on the HICARB diet had decreased LDL-chol (111 vs. 81, P less than .01) and unchanged HDL-chol and plasma TG concentrations).(

ABSTRACT

TRUNCATED AT 250 WORDS)

Links

Authors+Show Affiliations

,

Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona.

, ,

Source

Diabetes care 12:2 1989 Feb pg 102-7

MeSH

Adult
Blood Glucose
Cholesterol, HDL
Cholesterol, LDL
Diabetes Mellitus, Type 2
Diet, Diabetic
Dietary Carbohydrates
Dietary Fats
Fasting
Humans
Reference Values
Time Factors
Triglycerides

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2702893

Citation

Abbott, W G., et al. "Effects of Replacing Saturated Fat With Complex Carbohydrate in Diets of Subjects With NIDDM." Diabetes Care, vol. 12, no. 2, 1989, pp. 102-7.
Abbott WG, Boyce VL, Grundy SM, et al. Effects of replacing saturated fat with complex carbohydrate in diets of subjects with NIDDM. Diabetes Care. 1989;12(2):102-7.
Abbott, W. G., Boyce, V. L., Grundy, S. M., & Howard, B. V. (1989). Effects of replacing saturated fat with complex carbohydrate in diets of subjects with NIDDM. Diabetes Care, 12(2), pp. 102-7.
Abbott WG, et al. Effects of Replacing Saturated Fat With Complex Carbohydrate in Diets of Subjects With NIDDM. Diabetes Care. 1989;12(2):102-7. PubMed PMID: 2702893.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of replacing saturated fat with complex carbohydrate in diets of subjects with NIDDM. AU - Abbott,W G, AU - Boyce,V L, AU - Grundy,S M, AU - Howard,B V, PY - 1989/2/1/pubmed PY - 1989/2/1/medline PY - 1989/2/1/entrez SP - 102 EP - 7 JF - Diabetes care JO - Diabetes Care VL - 12 IS - 2 N2 - This study examined the safety of an isocaloric high-complex carbohydrate low-saturated fat diet (HICARB) in obese patients with non-insulin-dependent diabetes mellitus (NIDDM). Although hypocaloric diets should be recommended to these patients, many find compliance with this diet difficult; therefore, the safety of an isocaloric increase in dietary carbohydrate needs assessment. Lipoprotein cholesterol and triglyceride (TG, mg/dl) concentrations in isocaloric high-fat and HICARB diets were compared in 7 NIDDM subjects (fat 32 +/- 3%, fasting glucose 190 +/- 38 mg/dl) and 6 nondiabetic subjects (fat 33 +/- 5%). They ate a high-fat diet (43% carbohydrate; 42% fat, polyunsaturated to saturated 0.3; fiber 9 g/1000 kcal; cholesterol 550 mg/day) for 7-10 days. Control subjects (3 NIDDM, 3 nondiabetic) continued this diet for 5 wk. The 13 subjects changed to a HICARB diet (65% carbohydrate; 21% fat, polyunsaturated to saturated 1.2; fiber 18 g/1000 kcal; cholesterol 550 mg/day) for 5 wk. NIDDM subjects on the HICARB diet had decreased low-density lipoprotein cholesterol (LDL-chol) concentrations (107 vs. 82, P less than .001), but their high-density lipoprotein cholesterol (HDL-chol) concentrations, glucose, and body weight were unchanged. Changes in total plasma TG concentrations in NIDDM subjects were heterogeneous. Concentrations were either unchanged or had decreased in 5 and increased in 2 NIDDM subjects. Nondiabetic subjects on the HICARB diet had decreased LDL-chol (111 vs. 81, P less than .01) and unchanged HDL-chol and plasma TG concentrations).(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0149-5992 UR - https://www.unboundmedicine.com/medline/citation/2702893/Effects_of_replacing_saturated_fat_with_complex_carbohydrate_in_diets_of_subjects_with_NIDDM_ L2 - https://medlineplus.gov/diabeticdiet.html DB - PRIME DP - Unbound Medicine ER -