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Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report.
J Med Case Rep. 2016 Mar 25; 10:74.JM

Abstract

BACKGROUND

Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern. Symptoms often include an insidious onset of dysphagia resulting in weight loss. In a patient presenting with super early-stage verrucous carcinoma, we were able to eliminate the aberration using endoscopic submucosal dissection.

CASE PRESENTATION

An asymptomatic 68-year-old Asian man was found to have an abnormality in his esophagus. The abnormality was discovered, by chance, in a barium study for a health checkup. Esophagogastroduodenoscopy revealed a 1-centimeter polypoid lesion covered with squamous epithelium. Biopsies showed squamous high-grade intraepithelial neoplasia. An endoscopic submucosal dissection was performed and the histopathological findings showed a well-differentiated squamous cell carcinoma with hyperkeratosis with a church spire configuration. These features are consistent with the growth pattern of verrucous carcinoma.

CONCLUSIONS

Verrucous carcinoma can manifest as a small mass with nonclinical symptoms and endoscopic submucosal dissection is useful as a curative treatment. We must consider that verrucous carcinoma can manifest as appearance of a polyp that is not papillary or warty-like with and without extensive superficial growth appearance.

Authors+Show Affiliations

Department of Endoscopy, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Endoscopy, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan. masakato89@gmail.com.Department of Gastroenterology and Hepatology, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Pathology, Clinical Service, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Endoscopy, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Endoscopy, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Gastroenterology and Hepatology, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Endoscopy, The Jikei University Katsushika Medical Center, 6-41-2 Aoto Katsushika-ku, Tokyo, 125-8506, Japan.Department of Endoscopy, The Jikei University School of Medicine, 3-25-8 Nishishinbashi Minato-ku, Tokyo, 105-8461, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27036299

Citation

Abe, Takahiro, et al. "Endoscopic Submucosal Dissection for an Atypical Small Verrucous Carcinoma: a Case Report." Journal of Medical Case Reports, vol. 10, 2016, p. 74.
Abe T, Kato M, Itagaki M, et al. Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report. J Med Case Rep. 2016;10:74.
Abe, T., Kato, M., Itagaki, M., Hamatani, S., Kawahara, Y., Ito, S., Aizawa, Y., Matsuda, K., & Sumiyama, K. (2016). Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report. Journal of Medical Case Reports, 10, 74. https://doi.org/10.1186/s13256-016-0866-y
Abe T, et al. Endoscopic Submucosal Dissection for an Atypical Small Verrucous Carcinoma: a Case Report. J Med Case Rep. 2016 Mar 25;10:74. PubMed PMID: 27036299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report. AU - Abe,Takahiro, AU - Kato,Masayuki, AU - Itagaki,Munenori, AU - Hamatani,Sigeharu, AU - Kawahara,Yosuke, AU - Ito,Shuji, AU - Aizawa,Yoshio, AU - Matsuda,Koji, AU - Sumiyama,Kazuki, Y1 - 2016/03/25/ PY - 2015/11/10/received PY - 2016/03/09/accepted PY - 2016/4/3/entrez PY - 2016/4/3/pubmed PY - 2016/12/20/medline KW - Endoscopic submucosal dissection KW - Esophagus KW - Verrucous carcinoma SP - 74 EP - 74 JF - Journal of medical case reports JO - J Med Case Rep VL - 10 N2 - BACKGROUND: Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern. Symptoms often include an insidious onset of dysphagia resulting in weight loss. In a patient presenting with super early-stage verrucous carcinoma, we were able to eliminate the aberration using endoscopic submucosal dissection. CASE PRESENTATION: An asymptomatic 68-year-old Asian man was found to have an abnormality in his esophagus. The abnormality was discovered, by chance, in a barium study for a health checkup. Esophagogastroduodenoscopy revealed a 1-centimeter polypoid lesion covered with squamous epithelium. Biopsies showed squamous high-grade intraepithelial neoplasia. An endoscopic submucosal dissection was performed and the histopathological findings showed a well-differentiated squamous cell carcinoma with hyperkeratosis with a church spire configuration. These features are consistent with the growth pattern of verrucous carcinoma. CONCLUSIONS: Verrucous carcinoma can manifest as a small mass with nonclinical symptoms and endoscopic submucosal dissection is useful as a curative treatment. We must consider that verrucous carcinoma can manifest as appearance of a polyp that is not papillary or warty-like with and without extensive superficial growth appearance. SN - 1752-1947 UR - https://www.unboundmedicine.com/medline/citation/27036299/Endoscopic_submucosal_dissection_for_an_atypical_small_verrucous_carcinoma:_a_case_report_ L2 - https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-0866-y DB - PRIME DP - Unbound Medicine ER -