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The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat.
J Nutr. 1989 Apr; 119(4):581-5.JN

Abstract

The dependence of liver retinyl ester (vitamin A ester) composition on dietary fatty acid composition was studied in rats. Weanling male Sprague-Dawley rats were fed purified test diets containing 8% of one of 10 test triglycerides (either tributyrin, tricaproin, tricaprylin, tricaprin, trilaurin, trimyristin, tripalmitin, tristearin, triolein, trilinolein) or corn oil (a mixed triglyceride) for 23 d after an initial 1-wk stabilization period. Essential fatty acids were provided by safflower oil (8 g/kg diet). Total liver fatty acid composition showed the expected responses to dietary fatty acid intake; short-chain and medium-chain fatty acids were readily elongated to palmitate and stearate, and palmitate and stearate were readily desaturated. Consumption of oleate or linoleate (as their triglycerides) markedly enriched their concentrations in liver lipids. The proportions of palmitate were generally greater in liver retinyl esters than in total liver fatty acids, and the proportions of oleate were less. However, retinyl ester composition was significantly affected by dietary triglyceride, particularly by diets providing long-chain fatty acids. Total liver vitamin A levels were depressed in the group fed trilinolein.

Authors+Show Affiliations

Department of Biochemistry, Iowa State University, Ames 50011.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

2703916

Citation

Furr, H C., et al. "The Effect of Dietary Fatty Acid Composition On Liver Retinyl Ester (vitamin a Ester) Composition in the Rat." The Journal of Nutrition, vol. 119, no. 4, 1989, pp. 581-5.
Furr HC, Clifford AJ, Smith LM, et al. The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. J Nutr. 1989;119(4):581-5.
Furr, H. C., Clifford, A. J., Smith, L. M., & Olson, J. A. (1989). The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. The Journal of Nutrition, 119(4), 581-5.
Furr HC, et al. The Effect of Dietary Fatty Acid Composition On Liver Retinyl Ester (vitamin a Ester) Composition in the Rat. J Nutr. 1989;119(4):581-5. PubMed PMID: 2703916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. AU - Furr,H C, AU - Clifford,A J, AU - Smith,L M, AU - Olson,J A, PY - 1989/4/1/pubmed PY - 1989/4/1/medline PY - 1989/4/1/entrez SP - 581 EP - 5 JF - The Journal of nutrition JO - J Nutr VL - 119 IS - 4 N2 - The dependence of liver retinyl ester (vitamin A ester) composition on dietary fatty acid composition was studied in rats. Weanling male Sprague-Dawley rats were fed purified test diets containing 8% of one of 10 test triglycerides (either tributyrin, tricaproin, tricaprylin, tricaprin, trilaurin, trimyristin, tripalmitin, tristearin, triolein, trilinolein) or corn oil (a mixed triglyceride) for 23 d after an initial 1-wk stabilization period. Essential fatty acids were provided by safflower oil (8 g/kg diet). Total liver fatty acid composition showed the expected responses to dietary fatty acid intake; short-chain and medium-chain fatty acids were readily elongated to palmitate and stearate, and palmitate and stearate were readily desaturated. Consumption of oleate or linoleate (as their triglycerides) markedly enriched their concentrations in liver lipids. The proportions of palmitate were generally greater in liver retinyl esters than in total liver fatty acids, and the proportions of oleate were less. However, retinyl ester composition was significantly affected by dietary triglyceride, particularly by diets providing long-chain fatty acids. Total liver vitamin A levels were depressed in the group fed trilinolein. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/2703916/The_effect_of_dietary_fatty_acid_composition_on_liver_retinyl_ester__vitamin_A_ester__composition_in_the_rat_ L2 - https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/119.4.581 DB - PRIME DP - Unbound Medicine ER -