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Reactivation tuberculosis: role of surveillance.
Expert Rev Anti Infect Ther. 2016; 14(5):501-9.ER

Abstract

The incidence and death rates from tuberculosis (TB) have declined through concerted efforts in the diagnosis and treatment of active disease. Despite this, 9.6 million new cases and 1.1 million deaths in 2014 are unacceptably high. To decrease the rates of TB further, the huge number of persons with latent TB infection (LTBI) from whom new cases will arise has to be addressed with a sense of priority. Identifying the highest risk groups and providing effective treatment has been shown to decrease active TB. Further research to refine the predictors of reactivation and shorter effective treatments are urgently needed. Implementing intensified case finding, testing and treatment for LTBI will require continued investment in health care capacity at multiple levels.

Authors+Show Affiliations

a Global and Immigrant Health , Baylor College of Medicine , Houston , TX , USA.b Pulmonology, Department of Internal Medicine , Baylor College of Medicine , Houston , TX , USA.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

27042967

Citation

DiNardo, Andrew R., and Elizabeth Guy. "Reactivation Tuberculosis: Role of Surveillance." Expert Review of Anti-infective Therapy, vol. 14, no. 5, 2016, pp. 501-9.
DiNardo AR, Guy E. Reactivation tuberculosis: role of surveillance. Expert Rev Anti Infect Ther. 2016;14(5):501-9.
DiNardo, A. R., & Guy, E. (2016). Reactivation tuberculosis: role of surveillance. Expert Review of Anti-infective Therapy, 14(5), 501-9. https://doi.org/10.1586/14787210.2016.1173541
DiNardo AR, Guy E. Reactivation Tuberculosis: Role of Surveillance. Expert Rev Anti Infect Ther. 2016;14(5):501-9. PubMed PMID: 27042967.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reactivation tuberculosis: role of surveillance. AU - DiNardo,Andrew R, AU - Guy,Elizabeth, PY - 2016/4/5/entrez PY - 2016/4/5/pubmed PY - 2016/12/15/medline KW - HIV KW - Tuberculosis KW - intensive case finding KW - latent tuberculosis therapy KW - reactivation SP - 501 EP - 9 JF - Expert review of anti-infective therapy JO - Expert Rev Anti Infect Ther VL - 14 IS - 5 N2 - The incidence and death rates from tuberculosis (TB) have declined through concerted efforts in the diagnosis and treatment of active disease. Despite this, 9.6 million new cases and 1.1 million deaths in 2014 are unacceptably high. To decrease the rates of TB further, the huge number of persons with latent TB infection (LTBI) from whom new cases will arise has to be addressed with a sense of priority. Identifying the highest risk groups and providing effective treatment has been shown to decrease active TB. Further research to refine the predictors of reactivation and shorter effective treatments are urgently needed. Implementing intensified case finding, testing and treatment for LTBI will require continued investment in health care capacity at multiple levels. SN - 1744-8336 UR - https://www.unboundmedicine.com/medline/citation/27042967/Reactivation_tuberculosis:_role_of_surveillance_ L2 - https://www.tandfonline.com/doi/full/10.1586/14787210.2016.1173541 DB - PRIME DP - Unbound Medicine ER -