Tags

Type your tag names separated by a space and hit enter

Hepatitis E virus as an emerging zoonotic pathogen.
J Vet Sci. 2016 Mar; 17(1):1-11.JV

Abstract

Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can exceed 20% in pregnant women in some regions in India. The causative agent, hepatitis E virus (HEV), has been isolated from several animal species, including pigs. HEV genotypes 3 and 4 have been isolated from both humans and animals, and are recognized as zoonotic pathogens. Seroprevalence studies in animals and humans indirectly suggest that HEV infections occur worldwide. The virus is primarily transmitted to humans via undercooked animal meats in developed countries. Moreover, transfusion- and transplantation-mediated HEV infections have recently been reported. This review summarizes the general characteristics of hepatitis E, HEV infection status in animals and humans, the zoonotic transmission modes of HEV, and HEV vaccine development status.

Authors+Show Affiliations

Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

27051334

Citation

Park, Woo-Jung, et al. "Hepatitis E Virus as an Emerging Zoonotic Pathogen." Journal of Veterinary Science, vol. 17, no. 1, 2016, pp. 1-11.
Park WJ, Park BJ, Ahn HS, et al. Hepatitis E virus as an emerging zoonotic pathogen. J Vet Sci. 2016;17(1):1-11.
Park, W. J., Park, B. J., Ahn, H. S., Lee, J. B., Park, S. Y., Song, C. S., Lee, S. W., Yoo, H. S., & Choi, I. S. (2016). Hepatitis E virus as an emerging zoonotic pathogen. Journal of Veterinary Science, 17(1), 1-11. https://doi.org/10.4142/jvs.2016.17.1.1
Park WJ, et al. Hepatitis E Virus as an Emerging Zoonotic Pathogen. J Vet Sci. 2016;17(1):1-11. PubMed PMID: 27051334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatitis E virus as an emerging zoonotic pathogen. AU - Park,Woo-Jung, AU - Park,Byung-Joo, AU - Ahn,Hee-Seop, AU - Lee,Joong-Bok, AU - Park,Seung-Yong, AU - Song,Chang-Seon, AU - Lee,Sang-Won, AU - Yoo,Han-Sang, AU - Choi,In-Soo, Y1 - 2016/03/22/ PY - 2015/01/20/received PY - 2015/07/27/revised PY - 2015/08/22/accepted PY - 2016/4/7/entrez PY - 2016/4/7/pubmed PY - 2016/12/15/medline KW - hepatitis E KW - hepatitis E virus KW - pig KW - transmission KW - zoonotic pathogen SP - 1 EP - 11 JF - Journal of veterinary science JO - J Vet Sci VL - 17 IS - 1 N2 - Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can exceed 20% in pregnant women in some regions in India. The causative agent, hepatitis E virus (HEV), has been isolated from several animal species, including pigs. HEV genotypes 3 and 4 have been isolated from both humans and animals, and are recognized as zoonotic pathogens. Seroprevalence studies in animals and humans indirectly suggest that HEV infections occur worldwide. The virus is primarily transmitted to humans via undercooked animal meats in developed countries. Moreover, transfusion- and transplantation-mediated HEV infections have recently been reported. This review summarizes the general characteristics of hepatitis E, HEV infection status in animals and humans, the zoonotic transmission modes of HEV, and HEV vaccine development status. SN - 1976-555X UR - https://www.unboundmedicine.com/medline/citation/27051334/Hepatitis_E_virus_as_an_emerging_zoonotic_pathogen_ L2 - https://www.vetsci.org/DOIx.php?id=10.4142/jvs.2016.17.1.1 DB - PRIME DP - Unbound Medicine ER -