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[Clinical characteristics of orthostatic hypertension with hemodynamic response of vasovagal syncope and postural orthostatic tachycardia syndrome in children and adolescents].
Zhonghua Er Ke Za Zhi. 2016 Apr; 54(4):264-8.ZE

Abstract

OBJECTIVE

To analyze the clinical characteristics of orthostatic hypertension (OHT) with hemodynamic response of vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) in children and adolescents.

METHOD

Children and adolescents admitted to the Second Xiangya Hospital from July 2008 to April 2015 were included, and divided into three groups according to the results of head-up tilt test (HUTT): OHT group, OHT+ VVS group, OHT+ POTS group. The clinical characteristics were analyzed.

RESULT

Totally 629 cases were included, 300 cases in OHT group, 264 cases in OHT+ VVS group and 65 cases in OHT+ POTS group. Syncope and dizziness were the main symptoms of the three groups, and the proportion of patients complaining syncope in OHT+ VVS group was higher than that in OHT group (49.6% vs. 35.7%, χ(2)=11.211, P<0.05) and in OHT+ POTS group (49.6% vs. 27.7%, χ(2)=10.123, P<0.05). Baseline heart rate (HR)((78±14) beat/min vs. (77±12) beat/min, t=2.570, P<0.05), HUTT 3 min HR ((100±14) beat/min vs. (94±13) beat/min, t=17.464, P<0.05) and ΔHR ((22±12) beat/min vs. (17±9) beat/min, t=19.303, P<0.05) were higher in OHT+ VVS group than in OHT group. When compared with OHT group, baseline systolic blood pressure (SBP) ((105±10) mmHg(1 mmHg=0.133 kPa) vs. (103±10) mmHg, t=4.918, P<0.05), HUTT 3 min SBP((114±10) mmHg vs. (113±11) mmHg, t=4.046, P<0.05), baseline diastolic blood pressure (DBP)((64±6) mmHg vs. (63±7) mmHg, t=2.618, P<0.05), HUTT 3 min DBP((78±8) mmHg vs. (77±8) mmHg, t=3.302, P<0.05), HUTT 3 min HR ((107±14) beat/min vs. (94±13) beat/min, t=24.229, P<0.05) and ΔHR ((32±11) beat/min vs. (17±9) beat/min, t=39.146, P<0.05) in OHT+ POTS group were significantly higher, and baseline HR((75±14) beat/min vs. (77±12) beat/min, t=-4.221, P<0.05)in OHT+ POTS group was lower.

CONCLUSION

OHT with higher supine HR, upright HR and HR change is more susceptible to being complicated with VVS, while OHT with higher supine and upright SBP, higher supine and upright DBP and lower supine HR is more susceptible to being accompanied by POTS.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Zou RM
Department of Pediatric Cardiovascular Diseases, Children's Medical Center, Second Xiangya Hospital of Central South University, Changsha 410011, China.
Wang C
No affiliation info available
Wu LJ
No affiliation info available
Luo XM
No affiliation info available
Lin P
No affiliation info available
Li F
No affiliation info available
Xie ZW
No affiliation info available

MeSH

AdolescentBlood PressureChildDizzinessHeart RateHemodynamicsHumansHypertensionPostural Orthostatic Tachycardia SyndromeSyncope, VasovagalTilt-Table Test

Pub Type(s)

Journal Article

Language

chi

PubMed ID

27055424

Citation

Zou, R M., et al. "[Clinical Characteristics of Orthostatic Hypertension With Hemodynamic Response of Vasovagal Syncope and Postural Orthostatic Tachycardia Syndrome in Children and Adolescents]." Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics, vol. 54, no. 4, 2016, pp. 264-8.
Zou RM, Wang C, Wu LJ, et al. [Clinical characteristics of orthostatic hypertension with hemodynamic response of vasovagal syncope and postural orthostatic tachycardia syndrome in children and adolescents]. Zhonghua Er Ke Za Zhi. 2016;54(4):264-8.
Zou, R. M., Wang, C., Wu, L. J., Luo, X. M., Lin, P., Li, F., & Xie, Z. W. (2016). [Clinical characteristics of orthostatic hypertension with hemodynamic response of vasovagal syncope and postural orthostatic tachycardia syndrome in children and adolescents]. Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics, 54(4), 264-8. https://doi.org/10.3760/cma.j.issn.0578-1310.2016.04.007
Zou RM, et al. [Clinical Characteristics of Orthostatic Hypertension With Hemodynamic Response of Vasovagal Syncope and Postural Orthostatic Tachycardia Syndrome in Children and Adolescents]. Zhonghua Er Ke Za Zhi. 2016;54(4):264-8. PubMed PMID: 27055424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical characteristics of orthostatic hypertension with hemodynamic response of vasovagal syncope and postural orthostatic tachycardia syndrome in children and adolescents]. AU - Zou,R M, AU - Wang,C, AU - Wu,L J, AU - Luo,X M, AU - Lin,P, AU - Li,F, AU - Xie,Z W, PY - 2016/4/9/entrez PY - 2016/4/9/pubmed PY - 2017/1/31/medline SP - 264 EP - 8 JF - Zhonghua er ke za zhi = Chinese journal of pediatrics JO - Zhonghua Er Ke Za Zhi VL - 54 IS - 4 N2 - OBJECTIVE: To analyze the clinical characteristics of orthostatic hypertension (OHT) with hemodynamic response of vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) in children and adolescents. METHOD: Children and adolescents admitted to the Second Xiangya Hospital from July 2008 to April 2015 were included, and divided into three groups according to the results of head-up tilt test (HUTT): OHT group, OHT+ VVS group, OHT+ POTS group. The clinical characteristics were analyzed. RESULT: Totally 629 cases were included, 300 cases in OHT group, 264 cases in OHT+ VVS group and 65 cases in OHT+ POTS group. Syncope and dizziness were the main symptoms of the three groups, and the proportion of patients complaining syncope in OHT+ VVS group was higher than that in OHT group (49.6% vs. 35.7%, χ(2)=11.211, P<0.05) and in OHT+ POTS group (49.6% vs. 27.7%, χ(2)=10.123, P<0.05). Baseline heart rate (HR)((78±14) beat/min vs. (77±12) beat/min, t=2.570, P<0.05), HUTT 3 min HR ((100±14) beat/min vs. (94±13) beat/min, t=17.464, P<0.05) and ΔHR ((22±12) beat/min vs. (17±9) beat/min, t=19.303, P<0.05) were higher in OHT+ VVS group than in OHT group. When compared with OHT group, baseline systolic blood pressure (SBP) ((105±10) mmHg(1 mmHg=0.133 kPa) vs. (103±10) mmHg, t=4.918, P<0.05), HUTT 3 min SBP((114±10) mmHg vs. (113±11) mmHg, t=4.046, P<0.05), baseline diastolic blood pressure (DBP)((64±6) mmHg vs. (63±7) mmHg, t=2.618, P<0.05), HUTT 3 min DBP((78±8) mmHg vs. (77±8) mmHg, t=3.302, P<0.05), HUTT 3 min HR ((107±14) beat/min vs. (94±13) beat/min, t=24.229, P<0.05) and ΔHR ((32±11) beat/min vs. (17±9) beat/min, t=39.146, P<0.05) in OHT+ POTS group were significantly higher, and baseline HR((75±14) beat/min vs. (77±12) beat/min, t=-4.221, P<0.05)in OHT+ POTS group was lower. CONCLUSION: OHT with higher supine HR, upright HR and HR change is more susceptible to being complicated with VVS, while OHT with higher supine and upright SBP, higher supine and upright DBP and lower supine HR is more susceptible to being accompanied by POTS. SN - 0578-1310 UR - https://www.unboundmedicine.com/medline/citation/27055424/[Clinical_characteristics_of_orthostatic_hypertension_with_hemodynamic_response_of_vasovagal_syncope_and_postural_orthostatic_tachycardia_syndrome_in_children_and_adolescents]_ DB - PRIME DP - Unbound Medicine ER -