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Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus.
Emerg Infect Dis. 2016 06; 22(6):1071-4.EI

Abstract

We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

27070733

Citation

Crameri, Gary, et al. "Experimental Infection and Response to Rechallenge of Alpacas With Middle East Respiratory Syndrome Coronavirus." Emerging Infectious Diseases, vol. 22, no. 6, 2016, pp. 1071-4.
Crameri G, Durr PA, Klein R, et al. Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus. Emerg Infect Dis. 2016;22(6):1071-4.
Crameri, G., Durr, P. A., Klein, R., Foord, A., Yu, M., Riddell, S., Haining, J., Johnson, D., Hemida, M. G., Barr, J., Peiris, M., Middleton, D., & Wang, L. F. (2016). Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus. Emerging Infectious Diseases, 22(6), 1071-4. https://doi.org/10.3201/eid2206.160007
Crameri G, et al. Experimental Infection and Response to Rechallenge of Alpacas With Middle East Respiratory Syndrome Coronavirus. Emerg Infect Dis. 2016;22(6):1071-4. PubMed PMID: 27070733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus. AU - Crameri,Gary, AU - Durr,Peter A, AU - Klein,Reuben, AU - Foord,Adam, AU - Yu,Meng, AU - Riddell,Sarah, AU - Haining,Jessica, AU - Johnson,Dayna, AU - Hemida,Maged G, AU - Barr,Jennifer, AU - Peiris,Malik, AU - Middleton,Deborah, AU - Wang,Lin-Fa, Y1 - 2016/06/15/ PY - 2016/4/13/entrez PY - 2016/4/14/pubmed PY - 2018/1/13/medline KW - MERS-CoV KW - Middle East respiratory syndrome KW - SARS KW - alpaca KW - camel KW - coronavirus KW - experimental animal model KW - infection KW - rechallenge KW - severe acute respiratory syndrome KW - shedding KW - vaccine KW - viruses KW - zoonoses SP - 1071 EP - 4 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 22 IS - 6 N2 - We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus. SN - 1080-6059 UR - https://www.unboundmedicine.com/medline/citation/27070733/Experimental_Infection_and_Response_to_Rechallenge_of_Alpacas_with_Middle_East_Respiratory_Syndrome_Coronavirus_ L2 - https://doi.org/10.3201/eid2206.160007 DB - PRIME DP - Unbound Medicine ER -