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Phytochemical analysis, antimicrobial, antioxidant activities and total phenols of Ferulago carduchorum in two vegetative stages (flower and fruit).
Pak J Pharm Sci. 2016 Mar; 29(2):623-8.PJ

Abstract

Ferulago carduchorum (Apiaceae family) is an endemic plant of Iran. The crude extract and four fractions of aerial parts of F. carduchorum in two vegetative stages (flower and fruit) were studied for their total phenolic contents, antimicrobial and antioxidant activities using folin-ciocalteu assay, micro dilution method and DPPH assay, respectively. The results indicated that the best antioxidant activity was determined in flower crude extract (IC50=0.44 mg/mL). The flower ethyl acetate fraction (FLE) showed better antimicrobial and antifungal activities than other fractions. So, FLE was selected for phytochemical investigations, resulting in isolation of a flavonoid (hesperetin). Hesperetin showed antimicrobial activity. The results showed that the antimicrobial and antioxidant effects during the flowering are obviously more than the fruit season.

Authors+Show Affiliations

Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran / Department of Traditional Pharmacy, Faculty of Traditional Medicine and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.Department of Drug and Food Control, Faculty of Pharmacy and Pharmaceutical Quality Assurance Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design & Development Research Center, Tehran University of Medical Sciences, Tehran, Iran / Department of Traditional Pharmacy, Faculty of Traditional Medicine and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran / Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC, Canada.

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

27087085

Citation

Golfakhrabadi, Fereshteh, et al. "Phytochemical Analysis, Antimicrobial, Antioxidant Activities and Total Phenols of Ferulago Carduchorum in Two Vegetative Stages (flower and Fruit)." Pakistan Journal of Pharmaceutical Sciences, vol. 29, no. 2, 2016, pp. 623-8.
Golfakhrabadi F, Shams Ardekani MR, Saeidnia S, et al. Phytochemical analysis, antimicrobial, antioxidant activities and total phenols of Ferulago carduchorum in two vegetative stages (flower and fruit). Pak J Pharm Sci. 2016;29(2):623-8.
Golfakhrabadi, F., Shams Ardekani, M. R., Saeidnia, S., Yousefbeyk, F., Jamalifar, H., Ramezani, N., Akbarzadeh, T., & Khanavi, M. (2016). Phytochemical analysis, antimicrobial, antioxidant activities and total phenols of Ferulago carduchorum in two vegetative stages (flower and fruit). Pakistan Journal of Pharmaceutical Sciences, 29(2), 623-8.
Golfakhrabadi F, et al. Phytochemical Analysis, Antimicrobial, Antioxidant Activities and Total Phenols of Ferulago Carduchorum in Two Vegetative Stages (flower and Fruit). Pak J Pharm Sci. 2016;29(2):623-8. PubMed PMID: 27087085.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemical analysis, antimicrobial, antioxidant activities and total phenols of Ferulago carduchorum in two vegetative stages (flower and fruit). AU - Golfakhrabadi,Fereshteh, AU - Shams Ardekani,Mohammad Reza, AU - Saeidnia,Soodabeh, AU - Yousefbeyk,Fatemeh, AU - Jamalifar,Hossein, AU - Ramezani,Nasrin, AU - Akbarzadeh,Tahmineh, AU - Khanavi,Mahnaz, PY - 2016/4/19/entrez PY - 2016/4/19/pubmed PY - 2016/7/1/medline SP - 623 EP - 8 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 29 IS - 2 N2 - Ferulago carduchorum (Apiaceae family) is an endemic plant of Iran. The crude extract and four fractions of aerial parts of F. carduchorum in two vegetative stages (flower and fruit) were studied for their total phenolic contents, antimicrobial and antioxidant activities using folin-ciocalteu assay, micro dilution method and DPPH assay, respectively. The results indicated that the best antioxidant activity was determined in flower crude extract (IC50=0.44 mg/mL). The flower ethyl acetate fraction (FLE) showed better antimicrobial and antifungal activities than other fractions. So, FLE was selected for phytochemical investigations, resulting in isolation of a flavonoid (hesperetin). Hesperetin showed antimicrobial activity. The results showed that the antimicrobial and antioxidant effects during the flowering are obviously more than the fruit season. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/27087085/Phytochemical_analysis_antimicrobial_antioxidant_activities_and_total_phenols_of_Ferulago_carduchorum_in_two_vegetative_stages__flower_and_fruit__ DB - PRIME DP - Unbound Medicine ER -