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[THE EFFECTIVENESS OF THE CORRECTION OF ENDOTHELIAL DYSFUNCTION AND REMODELING OF THE BRACHIAL ARTERY WITH CONCENTRIC AND ECCENTRIC LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION].
Lik Sprava. 2015 Jul-SepLS

Abstract

The study involved patients with unstable angina (UA), comorbid hypertension (AH), myocardial infarction in 55.5% of cases. Systolic blood pressure was (163.2 ± 1.5) mm Hg. Art., diastolic blood pressure--(101.10 ± 0.67) mm Hg. Art., pulse pressure--(61.1 ± 17.0) mm Hg. Art. Examined patients underwent clinical studies, ECG in 12 conventional leads, echocardiography in M and B modes, Doppler ultrasonography of the brachial artery. To correct the detected change using standard combined therapy: perindopril 5-10 mg/day, bisoprolol--5-10 mg/day, atorvastatin--20 mg/day, acetylsalicylic acid--75-100 mg/day. Monitoring the treatment was carried out at 3; 6 and 12 months. Standard one-year comprehensive treatment of patients with UA with comorbid AH resulted in significant improvement of effective endothelial dysfunction in concentric and eccentric left ventricular hypertrophy in 3; 6 and 12 months, however, regression of hypertrophy brachial artery advancing much less mainly in concentric left ventricular hypertrophy.

Authors

Denesiuk EV
No affiliation info available

MeSH

Angina, UnstableAnticholesteremic AgentsAntihypertensive AgentsAspirinAtorvastatinBisoprololBlood PressureBrachial ArteryComorbidityDrug MonitoringFemaleFibrinolytic AgentsHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedMyocardial InfarctionPerindoprilTreatment OutcomeUltrasonographyVascular Remodeling

Pub Type(s)

Journal Article

Language

ukr

PubMed ID

27089719

Citation

Denesiuk, E V.. "[THE EFFECTIVENESS of the CORRECTION of ENDOTHELIAL DYSFUNCTION and REMODELING of the BRACHIAL ARTERY WITH CONCENTRIC and ECCENTRIC LEFT VENTRICULAR HYPERTROPHY in PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION]." Likars'ka Sprava, 2015, pp. 72-6.
Denesiuk EV. [THE EFFECTIVENESS OF THE CORRECTION OF ENDOTHELIAL DYSFUNCTION AND REMODELING OF THE BRACHIAL ARTERY WITH CONCENTRIC AND ECCENTRIC LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION]. Lik Sprava. 2015.
Denesiuk, E. V. (2015). [THE EFFECTIVENESS OF THE CORRECTION OF ENDOTHELIAL DYSFUNCTION AND REMODELING OF THE BRACHIAL ARTERY WITH CONCENTRIC AND ECCENTRIC LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION]. Likars'ka Sprava, (5-6), 72-6.
Denesiuk EV. [THE EFFECTIVENESS of the CORRECTION of ENDOTHELIAL DYSFUNCTION and REMODELING of the BRACHIAL ARTERY WITH CONCENTRIC and ECCENTRIC LEFT VENTRICULAR HYPERTROPHY in PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION]. Lik Sprava. 2015 Jul-Sep;(5-6)72-6. PubMed PMID: 27089719.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [THE EFFECTIVENESS OF THE CORRECTION OF ENDOTHELIAL DYSFUNCTION AND REMODELING OF THE BRACHIAL ARTERY WITH CONCENTRIC AND ECCENTRIC LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH UNSTABLE ANGINA WITH COMORBID HYPERTENSION]. A1 - Denesiuk,E V, PY - 2016/4/20/entrez PY - 2016/4/20/pubmed PY - 2016/5/6/medline SP - 72 EP - 6 JF - Likars'ka sprava JO - Lik Sprava IS - 5-6 N2 - The study involved patients with unstable angina (UA), comorbid hypertension (AH), myocardial infarction in 55.5% of cases. Systolic blood pressure was (163.2 ± 1.5) mm Hg. Art., diastolic blood pressure--(101.10 ± 0.67) mm Hg. Art., pulse pressure--(61.1 ± 17.0) mm Hg. Art. Examined patients underwent clinical studies, ECG in 12 conventional leads, echocardiography in M and B modes, Doppler ultrasonography of the brachial artery. To correct the detected change using standard combined therapy: perindopril 5-10 mg/day, bisoprolol--5-10 mg/day, atorvastatin--20 mg/day, acetylsalicylic acid--75-100 mg/day. Monitoring the treatment was carried out at 3; 6 and 12 months. Standard one-year comprehensive treatment of patients with UA with comorbid AH resulted in significant improvement of effective endothelial dysfunction in concentric and eccentric left ventricular hypertrophy in 3; 6 and 12 months, however, regression of hypertrophy brachial artery advancing much less mainly in concentric left ventricular hypertrophy. SN - 1019-5297 UR - https://www.unboundmedicine.com/medline/citation/27089719/[THE_EFFECTIVENESS_OF_THE_CORRECTION_OF_ENDOTHELIAL_DYSFUNCTION_AND_REMODELING_OF_THE_BRACHIAL_ARTERY_WITH_CONCENTRIC_AND_ECCENTRIC_LEFT_VENTRICULAR_HYPERTROPHY_IN_PATIENTS_WITH_UNSTABLE_ANGINA_WITH_COMORBID_HYPERTENSION]_ DB - PRIME DP - Unbound Medicine ER -

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