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Risk factors for recurrence in female urethral diverticulectomy: a retrospective study of 66 patients.
World J Urol. 2017 Jan; 35(1):139-144.WJ

Abstract

PURPOSE

We aimed to report surgical outcomes in female urethral diverticula and to investigate the risk factors for diverticula recurrence.

METHODS

A total of 66 patients underwent urethral diverticulectomies from January 2009 to October 2015 at out institution. Patient and diverticula characteristics were collected. Mean follow-up was 28.8 months (range 4-85 months). Recurrence was defined as requiring a repeat diverticulectomy.

RESULTS

Mean age was 44.9 years. Mean duration of symptoms was 28.1 months. Seven cases had previous urethral surgeries. Mean diverticula size was 2.8 cm. Main clinical symptoms included dribbling (n = 41), vaginal mass (n = 41), dysuria (n = 33), frequency/urgency (n = 29), infection (n = 24), stress urinary incontinence (SUI) (n = 20) and dyspareunia (n = 8). 10 cases had proximal diverticula, 10 cases had multiple diverticula, and 35 cases had horseshoe/circumferential diverticula. Postoperatively, the recurrence rate was 19.7 %. Preoperative SUI disappeared in 14 cases, and de novo SUI was developed in six cases. One case developed urethral stricture, and no cases reported urinary fistula. Among 60 cases with pathological results, neoplastic change was seen in one case (1.7 %). Besides, atypical hyperplasia (n = 2) and metaplasia (n = 3) were observed. Univariate analysis suggested that age, duration, follow-up, diverticula size and diverticula shape were not associated with surgical outcomes. Patients with multiple diverticula (p = 0.032), proximal diverticula (p = 0.042) and those with previous urethral procedures (p = 0.004) were at risk of recurrent diverticula confirmed by multivariate logistic regression analysis.

CONCLUSIONS

The surgical outcomes of urethral diverticulectomies were acceptable. Multiple diverticula, proximal diverticula and previous urethral surgery were three independent risk factors for recurrent diverticula.

Authors+Show Affiliations

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Medical Imaging, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China. wangkj@scu.edu.cn.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Guo xue xiang 37, Cheng Du, 610041, Sichuan, China. shen1177hx@163.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27095437

Citation

Zhou, Liang, et al. "Risk Factors for Recurrence in Female Urethral Diverticulectomy: a Retrospective Study of 66 Patients." World Journal of Urology, vol. 35, no. 1, 2017, pp. 139-144.
Zhou L, Luo DY, Feng SJ, et al. Risk factors for recurrence in female urethral diverticulectomy: a retrospective study of 66 patients. World J Urol. 2017;35(1):139-144.
Zhou, L., Luo, D. Y., Feng, S. J., Wei, X., Liu, Q., Lin, Y. F., Jin, T., Li, H., Wang, K. J., & Shen, H. (2017). Risk factors for recurrence in female urethral diverticulectomy: a retrospective study of 66 patients. World Journal of Urology, 35(1), 139-144. https://doi.org/10.1007/s00345-016-1815-5
Zhou L, et al. Risk Factors for Recurrence in Female Urethral Diverticulectomy: a Retrospective Study of 66 Patients. World J Urol. 2017;35(1):139-144. PubMed PMID: 27095437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors for recurrence in female urethral diverticulectomy: a retrospective study of 66 patients. AU - Zhou,Liang, AU - Luo,De-Yi, AU - Feng,Shi-Jian, AU - Wei,Xin, AU - Liu,Qi, AU - Lin,Yi-Fei, AU - Jin,Tao, AU - Li,Hong, AU - Wang,Kun-Jie, AU - Shen,Hong, Y1 - 2016/04/19/ PY - 2016/01/28/received PY - 2016/03/16/accepted PY - 2016/4/21/pubmed PY - 2017/6/15/medline PY - 2016/4/21/entrez KW - Diverticula KW - Recurrence KW - Risk factor KW - Urethral SP - 139 EP - 144 JF - World journal of urology JO - World J Urol VL - 35 IS - 1 N2 - PURPOSE: We aimed to report surgical outcomes in female urethral diverticula and to investigate the risk factors for diverticula recurrence. METHODS: A total of 66 patients underwent urethral diverticulectomies from January 2009 to October 2015 at out institution. Patient and diverticula characteristics were collected. Mean follow-up was 28.8 months (range 4-85 months). Recurrence was defined as requiring a repeat diverticulectomy. RESULTS: Mean age was 44.9 years. Mean duration of symptoms was 28.1 months. Seven cases had previous urethral surgeries. Mean diverticula size was 2.8 cm. Main clinical symptoms included dribbling (n = 41), vaginal mass (n = 41), dysuria (n = 33), frequency/urgency (n = 29), infection (n = 24), stress urinary incontinence (SUI) (n = 20) and dyspareunia (n = 8). 10 cases had proximal diverticula, 10 cases had multiple diverticula, and 35 cases had horseshoe/circumferential diverticula. Postoperatively, the recurrence rate was 19.7 %. Preoperative SUI disappeared in 14 cases, and de novo SUI was developed in six cases. One case developed urethral stricture, and no cases reported urinary fistula. Among 60 cases with pathological results, neoplastic change was seen in one case (1.7 %). Besides, atypical hyperplasia (n = 2) and metaplasia (n = 3) were observed. Univariate analysis suggested that age, duration, follow-up, diverticula size and diverticula shape were not associated with surgical outcomes. Patients with multiple diverticula (p = 0.032), proximal diverticula (p = 0.042) and those with previous urethral procedures (p = 0.004) were at risk of recurrent diverticula confirmed by multivariate logistic regression analysis. CONCLUSIONS: The surgical outcomes of urethral diverticulectomies were acceptable. Multiple diverticula, proximal diverticula and previous urethral surgery were three independent risk factors for recurrent diverticula. SN - 1433-8726 UR - https://www.unboundmedicine.com/medline/citation/27095437/Risk_factors_for_recurrence_in_female_urethral_diverticulectomy:_a_retrospective_study_of_66_patients_ DB - PRIME DP - Unbound Medicine ER -