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Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania.
Minerva Pediatr. 2016 Jun; 68(3):189-95.MP

Abstract

BACKGROUND

The aim of this study was to investigate the common etiologies, clinical and biological patterns of upper gastrointestinal bleeding (UGIB) in children from a hospital center in Northeast Romania.

METHODS

This seven-year retrospective study was performed from 2007 to 2013 in St. Mary Children's Emergency Hospital, Jassy, Romania and included all children who referred to our center with UGIB exteriorized by hematemesis or melena. Endoscopy was performed under conscious sedation/general anesthesia after the informed consent was obtained.

RESULTS

One hundred and three patients aged 1-18 years were included in this study. There were 57 males and 46 females with male to female ratio 1.2:1; 43.69% presented with hematemesis, 31.07% had melena and 25.24% had both. The most common causes of UGIB were erosive gastritis (33.98%), followed by esophagitis (14.56%), duodenitis (11.65%), duodenal ulcer (10.68%), gastric ulcer (5.83%), esophageal varices (4.85%), Mallory-Weiss syndrome (1.94%); multiple etiologies counted for 16.50% cases. A certain bleeding source was found in 34.95% cases, a possible one in 39.81% of the patients; the source could not be ascertained in 25.24% of cases. Nonsteroidal anti-inflammatory drug (NSAID) consumption was documented in in 17.51% of patients. The incidence of H. pylori infection was 36.89%.

CONCLUSIONS

The most common cause of of upper GI bleeding in our series was gastritis, followed by oesophagitis and duodenitis. Most of the patients presented with hematemesis; previous consumption of NSAIDs and H. pylori infection were associated with gastroduodenal ulceration and bleeding. Early endoscopy was associated with a higher detection rate of the bleeding source.

Authors+Show Affiliations

Department of Pediatrics, St. Mary Children's Emergency Hospital, Jassy, Romania - turti23@yahoo.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27125439

Citation

Gimiga, Nicoleta, et al. "Upper Gastrointestinal Bleeding in Children From a Hospital Center of Northeast Romania." Minerva Pediatrica, vol. 68, no. 3, 2016, pp. 189-95.
Gimiga N, Olaru C, Diaconescu S, et al. Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania. Minerva Pediatr. 2016;68(3):189-95.
Gimiga, N., Olaru, C., Diaconescu, S., Miron, I., & Burlea, M. (2016). Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania. Minerva Pediatrica, 68(3), 189-95.
Gimiga N, et al. Upper Gastrointestinal Bleeding in Children From a Hospital Center of Northeast Romania. Minerva Pediatr. 2016;68(3):189-95. PubMed PMID: 27125439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Upper gastrointestinal bleeding in children from a hospital center of Northeast Romania. AU - Gimiga,Nicoleta, AU - Olaru,Claudia, AU - Diaconescu,Smaranda, AU - Miron,Ingrith, AU - Burlea,Marin, PY - 2016/4/30/entrez PY - 2016/4/30/pubmed PY - 2017/9/5/medline SP - 189 EP - 95 JF - Minerva pediatrica JO - Minerva Pediatr VL - 68 IS - 3 N2 - BACKGROUND: The aim of this study was to investigate the common etiologies, clinical and biological patterns of upper gastrointestinal bleeding (UGIB) in children from a hospital center in Northeast Romania. METHODS: This seven-year retrospective study was performed from 2007 to 2013 in St. Mary Children's Emergency Hospital, Jassy, Romania and included all children who referred to our center with UGIB exteriorized by hematemesis or melena. Endoscopy was performed under conscious sedation/general anesthesia after the informed consent was obtained. RESULTS: One hundred and three patients aged 1-18 years were included in this study. There were 57 males and 46 females with male to female ratio 1.2:1; 43.69% presented with hematemesis, 31.07% had melena and 25.24% had both. The most common causes of UGIB were erosive gastritis (33.98%), followed by esophagitis (14.56%), duodenitis (11.65%), duodenal ulcer (10.68%), gastric ulcer (5.83%), esophageal varices (4.85%), Mallory-Weiss syndrome (1.94%); multiple etiologies counted for 16.50% cases. A certain bleeding source was found in 34.95% cases, a possible one in 39.81% of the patients; the source could not be ascertained in 25.24% of cases. Nonsteroidal anti-inflammatory drug (NSAID) consumption was documented in in 17.51% of patients. The incidence of H. pylori infection was 36.89%. CONCLUSIONS: The most common cause of of upper GI bleeding in our series was gastritis, followed by oesophagitis and duodenitis. Most of the patients presented with hematemesis; previous consumption of NSAIDs and H. pylori infection were associated with gastroduodenal ulceration and bleeding. Early endoscopy was associated with a higher detection rate of the bleeding source. SN - 1827-1715 UR - https://www.unboundmedicine.com/medline/citation/27125439/Upper_gastrointestinal_bleeding_in_children_from_a_hospital_center_of_Northeast_Romania_ L2 - http://www.minervamedica.it/index2.t?show=R15Y2016N03A0189 DB - PRIME DP - Unbound Medicine ER -