Tags

Type your tag names separated by a space and hit enter

Sexual, reproductive and contraceptive risk factors for carcinoma-in-situ of the uterine cervix in Sydney.
Med J Aust 1989; 150(3):125-30MJ

Abstract

Sexual, reproductive and contraceptive risk factors were investigated in a matched community-based case-control study of carcinoma-in-situ of the uterine cervix in Sydney. The risk was related strongly to the number of sexual partners: women who had had seven or more sexual partners in a lifetime had a six-fold increased risk compared with those with one or no partner. Early age at first sexual intercourse was also a risk factor, but this effect was reduced substantially after adjustment for the number of partners, with only a two-fold excess risk persisting for those with first intercourse before the age of 16 years as compared with those whose first sexual intercourse was at the age of 25 years or later. The long-term use of oral contraceptive agents was associated with an elevated risk (relative risk, 2.3 for more than six years of use); this effect was maintained for both oestrogen and progestogen doses. The risk increased with the number of induced abortions that had been undergone (relative risk, 2.2 for two or more abortions), but this effect was not statistically significant. A protective effect was found for women who had had a tubal ligation, for those who practised the rhythm method of birth control, and for women who breastfed. It is possible that these reduced risks may relate to unmeasured variables of life-style.

Authors+Show Affiliations

University of Sydney, NSW.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2716580

Citation

Brock, K E., et al. "Sexual, Reproductive and Contraceptive Risk Factors for Carcinoma-in-situ of the Uterine Cervix in Sydney." The Medical Journal of Australia, vol. 150, no. 3, 1989, pp. 125-30.
Brock KE, Berry G, Brinton LA, et al. Sexual, reproductive and contraceptive risk factors for carcinoma-in-situ of the uterine cervix in Sydney. Med J Aust. 1989;150(3):125-30.
Brock, K. E., Berry, G., Brinton, L. A., Kerr, C., MacLennan, R., Mock, P. A., & Shearman, R. P. (1989). Sexual, reproductive and contraceptive risk factors for carcinoma-in-situ of the uterine cervix in Sydney. The Medical Journal of Australia, 150(3), pp. 125-30.
Brock KE, et al. Sexual, Reproductive and Contraceptive Risk Factors for Carcinoma-in-situ of the Uterine Cervix in Sydney. Med J Aust. 1989 Feb 6;150(3):125-30. PubMed PMID: 2716580.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sexual, reproductive and contraceptive risk factors for carcinoma-in-situ of the uterine cervix in Sydney. AU - Brock,K E, AU - Berry,G, AU - Brinton,L A, AU - Kerr,C, AU - MacLennan,R, AU - Mock,P A, AU - Shearman,R P, PY - 1989/2/6/pubmed PY - 1989/2/6/medline PY - 1989/2/6/entrez KW - Age Factors KW - Australia KW - Behavior KW - Biology KW - Cancer KW - Cervical Cancer--etiology KW - Comparative Studies KW - Contraception KW - Contraceptive Agents KW - Contraceptive Agents, Female KW - Contraceptive Methods--side effects KW - Demographic Factors KW - Developed Countries KW - Developing Countries KW - Diseases KW - Family Planning KW - Longterm Effects KW - Neoplasms KW - Oceania KW - Oral Contraceptives--side effects KW - Population KW - Population Characteristics KW - Population Dynamics KW - Research Methodology KW - Risk Factors KW - Sex Behavior KW - Studies KW - Time Factors SP - 125 EP - 30 JF - The Medical journal of Australia JO - Med. J. Aust. VL - 150 IS - 3 N2 - Sexual, reproductive and contraceptive risk factors were investigated in a matched community-based case-control study of carcinoma-in-situ of the uterine cervix in Sydney. The risk was related strongly to the number of sexual partners: women who had had seven or more sexual partners in a lifetime had a six-fold increased risk compared with those with one or no partner. Early age at first sexual intercourse was also a risk factor, but this effect was reduced substantially after adjustment for the number of partners, with only a two-fold excess risk persisting for those with first intercourse before the age of 16 years as compared with those whose first sexual intercourse was at the age of 25 years or later. The long-term use of oral contraceptive agents was associated with an elevated risk (relative risk, 2.3 for more than six years of use); this effect was maintained for both oestrogen and progestogen doses. The risk increased with the number of induced abortions that had been undergone (relative risk, 2.2 for two or more abortions), but this effect was not statistically significant. A protective effect was found for women who had had a tubal ligation, for those who practised the rhythm method of birth control, and for women who breastfed. It is possible that these reduced risks may relate to unmeasured variables of life-style. SN - 0025-729X UR - https://www.unboundmedicine.com/medline/citation/2716580/Sexual_reproductive_and_contraceptive_risk_factors_for_carcinoma_in_situ_of_the_uterine_cervix_in_Sydney_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0025-729X&date=1989&volume=150&issue=3&spage=125 DB - PRIME DP - Unbound Medicine ER -