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Frequency and risk factors of functional gastro-intestinal disorders in a rural Indian population.
J Gastroenterol Hepatol. 2017 Feb; 32(2):378-387.JG

Abstract

BACKGROUND AND AIM

As best estimates on functional gastrointestinal disorders (FGIDs) prevalence are expected from community studies, which are scanty from Asia, we evaluated the prevalence and risk factors of FGIDs in a rural Indian community.

METHODS

House-to-house survey was undertaken by trained interviewers using translated-validated Rome III and hospital anxiety and depression questionnaires.

RESULT

Among 3426 subjects ≥ 18 years old from 3 villages in Uttar Pradesh, 84% participated, of whom 80% were finally analyzed. Of these 2774 subjects (age 38.4 ± 16.5 years, 1573 [56.7%] male), 2654 [95.7%] were vegetarian and 120 [4.3%] non-vegetarian. Socioeconomic classes were upper (16.7%), upper middle (15.1%), lower middle (22%), upper lower (22.2%), and lower (24%) using Prasad's Classification; 603 (21.7%) had FGIDs (413 [14.9%] dyspepsia, 75 [2.7%] irritable bowel syndrome (IBS) and 115 [4.1%] dyspepsia-IBS overlap), by Rome III criteria. In subjects with dyspepsia, 49/528 (9%) had epigastric pain, 141 (27%) postprandial distress syndromes (EPS, PDS) and 338 (64%) EPS-PDS overlap. IBS was more often diarrhea than constipation-predominant subtype. On univariate analysis, chewing tobacco, aerated drink, tea/coffee, disturbed sleep, vegetarianism, and anxiety parameters and presence of dyspepsia predicting occurrence of IBS were associated with FGIDs. On multivariate analysis, chewing tobacco, aerated soft drink, tea/coffee, vegetarianism, anxiety parameters, and presence of dyspepsia predicting IBS were significant.

CONCLUSION

Functional gastrointestinal disorders, particularly dyspepsia-IBS overlap, are common in rural Indian population; the risk factors included chewing tobacco, aerated soft drink, tea/coffee, vegetarian diet, disturbed sleep, anxiety, and dyspepsia predicting occurrence of IBS.

Authors+Show Affiliations

Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27262283

Citation

Ghoshal, Uday C., and Rajan Singh. "Frequency and Risk Factors of Functional Gastro-intestinal Disorders in a Rural Indian Population." Journal of Gastroenterology and Hepatology, vol. 32, no. 2, 2017, pp. 378-387.
Ghoshal UC, Singh R. Frequency and risk factors of functional gastro-intestinal disorders in a rural Indian population. J Gastroenterol Hepatol. 2017;32(2):378-387.
Ghoshal, U. C., & Singh, R. (2017). Frequency and risk factors of functional gastro-intestinal disorders in a rural Indian population. Journal of Gastroenterology and Hepatology, 32(2), 378-387. https://doi.org/10.1111/jgh.13465
Ghoshal UC, Singh R. Frequency and Risk Factors of Functional Gastro-intestinal Disorders in a Rural Indian Population. J Gastroenterol Hepatol. 2017;32(2):378-387. PubMed PMID: 27262283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Frequency and risk factors of functional gastro-intestinal disorders in a rural Indian population. AU - Ghoshal,Uday C, AU - Singh,Rajan, PY - 2016/05/30/accepted PY - 2016/6/6/pubmed PY - 2017/9/20/medline PY - 2016/6/6/entrez KW - Irritable bowel syndrome KW - constipation KW - diarrhea KW - epidemiology KW - functional GI diseases KW - functional dyspepsia SP - 378 EP - 387 JF - Journal of gastroenterology and hepatology JO - J. Gastroenterol. Hepatol. VL - 32 IS - 2 N2 - BACKGROUND AND AIM: As best estimates on functional gastrointestinal disorders (FGIDs) prevalence are expected from community studies, which are scanty from Asia, we evaluated the prevalence and risk factors of FGIDs in a rural Indian community. METHODS: House-to-house survey was undertaken by trained interviewers using translated-validated Rome III and hospital anxiety and depression questionnaires. RESULT: Among 3426 subjects ≥ 18 years old from 3 villages in Uttar Pradesh, 84% participated, of whom 80% were finally analyzed. Of these 2774 subjects (age 38.4 ± 16.5 years, 1573 [56.7%] male), 2654 [95.7%] were vegetarian and 120 [4.3%] non-vegetarian. Socioeconomic classes were upper (16.7%), upper middle (15.1%), lower middle (22%), upper lower (22.2%), and lower (24%) using Prasad's Classification; 603 (21.7%) had FGIDs (413 [14.9%] dyspepsia, 75 [2.7%] irritable bowel syndrome (IBS) and 115 [4.1%] dyspepsia-IBS overlap), by Rome III criteria. In subjects with dyspepsia, 49/528 (9%) had epigastric pain, 141 (27%) postprandial distress syndromes (EPS, PDS) and 338 (64%) EPS-PDS overlap. IBS was more often diarrhea than constipation-predominant subtype. On univariate analysis, chewing tobacco, aerated drink, tea/coffee, disturbed sleep, vegetarianism, and anxiety parameters and presence of dyspepsia predicting occurrence of IBS were associated with FGIDs. On multivariate analysis, chewing tobacco, aerated soft drink, tea/coffee, vegetarianism, anxiety parameters, and presence of dyspepsia predicting IBS were significant. CONCLUSION: Functional gastrointestinal disorders, particularly dyspepsia-IBS overlap, are common in rural Indian population; the risk factors included chewing tobacco, aerated soft drink, tea/coffee, vegetarian diet, disturbed sleep, anxiety, and dyspepsia predicting occurrence of IBS. SN - 1440-1746 UR - https://www.unboundmedicine.com/medline/citation/27262283/Frequency_and_risk_factors_of_functional_gastro_intestinal_disorders_in_a_rural_Indian_population_ L2 - https://doi.org/10.1111/jgh.13465 DB - PRIME DP - Unbound Medicine ER -