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Diterpenoid alkaloids from the roots of Aconitum brachypodum Diels.
J Asian Nat Prod Res. 2016 Sep; 18(9):908-12.JA

Abstract

A new diterpenoid alkaloid, named bullatine H (1), along with 10 known diterpenoid alkaloids were isolated from the roots of Aconitum brachypodum Diels (Ranunculaceae). The structure of 1 was elucidated by analysis of its spectroscopic data. It should be noted that compound 1 is the first example with 11, 13-dioxygenated denudatine-type diterpenoid alkaloid isolated from Aconitum brachypodum.

Authors+Show Affiliations

a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.a Yunnan Institute of Materia Medica , Kunming 650111 , China. b Yunnan Bai Yao Group Innovation and R&D Center , Kunming 650111 , China. c Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation , Kunming 650111 , China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27268073

Citation

Yang, Li-Guo, et al. "Diterpenoid Alkaloids From the Roots of Aconitum Brachypodum Diels." Journal of Asian Natural Products Research, vol. 18, no. 9, 2016, pp. 908-12.
Yang LG, Zhang YJ, Xie JY, et al. Diterpenoid alkaloids from the roots of Aconitum brachypodum Diels. J Asian Nat Prod Res. 2016;18(9):908-12.
Yang, L. G., Zhang, Y. J., Xie, J. Y., Xia, W. J., Zhang, H. Y., Tang, M. Y., Mei, S. X., Cui, T., Wang, J. K., & Zhu, Z. Y. (2016). Diterpenoid alkaloids from the roots of Aconitum brachypodum Diels. Journal of Asian Natural Products Research, 18(9), 908-12. https://doi.org/10.1080/10286020.2016.1173677
Yang LG, et al. Diterpenoid Alkaloids From the Roots of Aconitum Brachypodum Diels. J Asian Nat Prod Res. 2016;18(9):908-12. PubMed PMID: 27268073.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diterpenoid alkaloids from the roots of Aconitum brachypodum Diels. AU - Yang,Li-Guo, AU - Zhang,Ying-Jie, AU - Xie,Jia-Ying, AU - Xia,Wei-Jun, AU - Zhang,Hai-Yuan, AU - Tang,Meng-Yun, AU - Mei,Shuang-Xi, AU - Cui,Tao, AU - Wang,Jing-Kun, AU - Zhu,Zhao-Yun, Y1 - 2016/06/07/ PY - 2016/6/9/entrez PY - 2016/6/9/pubmed PY - 2017/2/6/medline KW - Aconitum brachypodum KW - Ranunculaceae KW - diterpenoid alkaloids KW - isolation KW - structure elucidation SP - 908 EP - 12 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 18 IS - 9 N2 - A new diterpenoid alkaloid, named bullatine H (1), along with 10 known diterpenoid alkaloids were isolated from the roots of Aconitum brachypodum Diels (Ranunculaceae). The structure of 1 was elucidated by analysis of its spectroscopic data. It should be noted that compound 1 is the first example with 11, 13-dioxygenated denudatine-type diterpenoid alkaloid isolated from Aconitum brachypodum. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/27268073/Diterpenoid_alkaloids_from_the_roots_of_Aconitum_brachypodum_Diels_ L2 - https://www.tandfonline.com/doi/full/10.1080/10286020.2016.1173677 DB - PRIME DP - Unbound Medicine ER -