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In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis.
ORL J Otorhinolaryngol Relat Spec. 2016; 78(4):187-92.OJ

Abstract

BACKGROUND

Voice and swallowing impairments can impact on both quality of life and survival. Unilateral vocal fold paralysis (UVFP) as a result of distant metastasis can cause breathy voice and aspiration. The purpose of this study is to develop and evaluate a less invasive and effective alternative therapy for UVFP.

METHODS

This was a retrospective review of prospectively enrolled patients at a tertiary referral center in Taiwan. Among a cohort of 177 patients who received intracordal hyaluronate injections, 2 had UVFP from distant metastasis and met the inclusion criteria. Vocal cord motion was recorded by videostroboscopy, and the normalized glottal gap area was measured. Voice quality, defined by speech language pathologists, and swallowing status were compared, and immediate complications after the injection were investigated.

RESULTS

Two patients with UVFP with M1 lesions (both lung) accepted the procedure. The glottal gap area was significantly improved 1 month after in-office hyaluronate injection. Voice quality and aspiration were also improved. No immediate complications were noted in either patient.

CONCLUSIONS

In-office intracordal hyaluronate injection is a safe and effective treatment for UVFP, providing a palliative method to help maintain the patient's voice and quality of life.

Authors+Show Affiliations

Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27270919

Citation

Soriano, Ronaldo G., et al. "In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis." ORL; Journal for Oto-rhino-laryngology and Its Related Specialties, vol. 78, no. 4, 2016, pp. 187-92.
Soriano RG, Pei YC, Fang TJ. In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis. ORL J Otorhinolaryngol Relat Spec. 2016;78(4):187-92.
Soriano, R. G., Pei, Y. C., & Fang, T. J. (2016). In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis. ORL; Journal for Oto-rhino-laryngology and Its Related Specialties, 78(4), 187-92. https://doi.org/10.1159/000446243
Soriano RG, Pei YC, Fang TJ. In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis. ORL J Otorhinolaryngol Relat Spec. 2016;78(4):187-92. PubMed PMID: 27270919.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In-Office Hyaluronate Injection Laryngoplasty as Palliative Treatment for Unilateral Vocal Fold Paralysis. AU - Soriano,Ronaldo G, AU - Pei,Yu-Chen, AU - Fang,Tuan-Jen, Y1 - 2016/06/08/ PY - 2015/12/29/received PY - 2016/04/12/accepted PY - 2016/6/9/entrez PY - 2016/6/9/pubmed PY - 2017/3/28/medline SP - 187 EP - 92 JF - ORL; journal for oto-rhino-laryngology and its related specialties JO - ORL J Otorhinolaryngol Relat Spec VL - 78 IS - 4 N2 - BACKGROUND: Voice and swallowing impairments can impact on both quality of life and survival. Unilateral vocal fold paralysis (UVFP) as a result of distant metastasis can cause breathy voice and aspiration. The purpose of this study is to develop and evaluate a less invasive and effective alternative therapy for UVFP. METHODS: This was a retrospective review of prospectively enrolled patients at a tertiary referral center in Taiwan. Among a cohort of 177 patients who received intracordal hyaluronate injections, 2 had UVFP from distant metastasis and met the inclusion criteria. Vocal cord motion was recorded by videostroboscopy, and the normalized glottal gap area was measured. Voice quality, defined by speech language pathologists, and swallowing status were compared, and immediate complications after the injection were investigated. RESULTS: Two patients with UVFP with M1 lesions (both lung) accepted the procedure. The glottal gap area was significantly improved 1 month after in-office hyaluronate injection. Voice quality and aspiration were also improved. No immediate complications were noted in either patient. CONCLUSIONS: In-office intracordal hyaluronate injection is a safe and effective treatment for UVFP, providing a palliative method to help maintain the patient's voice and quality of life. SN - 1423-0275 UR - https://www.unboundmedicine.com/medline/citation/27270919/In_Office_Hyaluronate_Injection_Laryngoplasty_as_Palliative_Treatment_for_Unilateral_Vocal_Fold_Paralysis_ L2 - https://www.karger.com?DOI=10.1159/000446243 DB - PRIME DP - Unbound Medicine ER -