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Ultrasound pattern of a rare skin disease: multiple miliaryosteoma cutis.
J Ultrasound 2016; 19(2):145-7JU

Abstract

PURPOSE

Multiple miliaryosteoma cutis (MMOC) is a rare nodular skin disease, characterized by tiny bone nodules in the dermis and subcutaneous tissue, presenting clinically as multiple normochromic papules and nodules, usually on the face. We described the case of MMOC of the face in a woman, ultrasonically evaluated with very high frequency probe.

MATERIALS AND METHODS

A 45-year-old patient with multiple papules, 3-5 mm in diameter, grouped in the frontal region. Skin ultrasound examination, cutaneous biopsy and laboratory evaluation were performed.

RESULTS

High-frequency ultrasound showed the presence of multiple hyperechogenic linear and roundish structures, associated by hypoechogenic shadow. The histology revealed a normal orthokeratotic stratified epithelium with fragment of mature lamellar bone localized at level of the reticular dermis. Laboratory evaluation was normal. According to the clinical, pathological, laboratory and instrumental analyses, a final diagnosis of miliaryosteoma cutis (or primary osteoma cutis not associated with Albright's hereditary osteodystrophy) was made.

CONCLUSION

In case of multiple papules of subcutaneous tissue, the diagnosis of MMOC, although rare, should be considered and high-frequency sonography, identifying the calcifications, suggests diagnosis.

Authors+Show Affiliations

Department of Radiology, San Gallicano Dermatologic Institute for Research and Care, Via Elio Chianesi 53, 00144 Rome, Italy.Department of Dermopathology, San Gallicano Dermatologic Institute for Research and Care, Rome, Italy.Department of Dermopathology, San Gallicano Dermatologic Institute for Research and Care, Rome, Italy.Department of Radiology, San Gallicano Dermatologic Institute for Research and Care, Via Elio Chianesi 53, 00144 Rome, Italy.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27298645

Citation

Elia, F, et al. "Ultrasound Pattern of a Rare Skin Disease: Multiple Miliaryosteoma Cutis." Journal of Ultrasound, vol. 19, no. 2, 2016, pp. 145-7.
Elia F, Paolino G, Donati M, et al. Ultrasound pattern of a rare skin disease: multiple miliaryosteoma cutis. J Ultrasound. 2016;19(2):145-7.
Elia, F., Paolino, G., Donati, M., & Solivetti, F. M. (2016). Ultrasound pattern of a rare skin disease: multiple miliaryosteoma cutis. Journal of Ultrasound, 19(2), pp. 145-7. doi:10.1007/s40477-015-0184-z.
Elia F, et al. Ultrasound Pattern of a Rare Skin Disease: Multiple Miliaryosteoma Cutis. J Ultrasound. 2016;19(2):145-7. PubMed PMID: 27298645.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ultrasound pattern of a rare skin disease: multiple miliaryosteoma cutis. AU - Elia,F, AU - Paolino,G, AU - Donati,M, AU - Solivetti,F M, Y1 - 2015/10/16/ PY - 2015/06/23/received PY - 2015/09/29/accepted PY - 2016/6/15/entrez PY - 2016/6/15/pubmed PY - 2016/6/15/medline KW - High-frequency sonography KW - Multiple calcifications KW - Osteoma cutis SP - 145 EP - 7 JF - Journal of ultrasound JO - J Ultrasound VL - 19 IS - 2 N2 - PURPOSE: Multiple miliaryosteoma cutis (MMOC) is a rare nodular skin disease, characterized by tiny bone nodules in the dermis and subcutaneous tissue, presenting clinically as multiple normochromic papules and nodules, usually on the face. We described the case of MMOC of the face in a woman, ultrasonically evaluated with very high frequency probe. MATERIALS AND METHODS: A 45-year-old patient with multiple papules, 3-5 mm in diameter, grouped in the frontal region. Skin ultrasound examination, cutaneous biopsy and laboratory evaluation were performed. RESULTS: High-frequency ultrasound showed the presence of multiple hyperechogenic linear and roundish structures, associated by hypoechogenic shadow. The histology revealed a normal orthokeratotic stratified epithelium with fragment of mature lamellar bone localized at level of the reticular dermis. Laboratory evaluation was normal. According to the clinical, pathological, laboratory and instrumental analyses, a final diagnosis of miliaryosteoma cutis (or primary osteoma cutis not associated with Albright's hereditary osteodystrophy) was made. CONCLUSION: In case of multiple papules of subcutaneous tissue, the diagnosis of MMOC, although rare, should be considered and high-frequency sonography, identifying the calcifications, suggests diagnosis. SN - 1876-7931 UR - https://www.unboundmedicine.com/medline/citation/27298645/Ultrasound_pattern_of_a_rare_skin_disease:_multiple_miliaryosteoma_cutis_ L2 - https://dx.doi.org/10.1007/s40477-015-0184-z DB - PRIME DP - Unbound Medicine ER -