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Association of HLA antigens with diabetes mellitus in an Iraqi population.
Dis Markers. 1989 Apr-Jun; 7(2):79-85.DM

Abstract

HLA antigen frequencies in 50 patients with IDDM, 56 patients with NIDDM, and 109 normal Iraqi controls were studied. Three families with one patient suffering from IDDM were also studied. No significant HLA antigens associated with NIDDM were found. Highly significant association of HLA, A1, B8, DR3, and DR4 were found in patients with IDDM as compared to normal individuals. The frequency of HLA-B5 and DR2 were significantly decreased in patients with IDDM. In contrast to previously reported findings in Caucasoids there was no significant association with B15 and a negative association with HLA-B5, not with B7. These results were compared with published findings for Arabs and other ethnic populations.

Authors+Show Affiliations

Department of Microbiology, College of Medicine, Basrah, Iraq.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2731409

Citation

Jabbar, A A., et al. "Association of HLA Antigens With Diabetes Mellitus in an Iraqi Population." Disease Markers, vol. 7, no. 2, 1989, pp. 79-85.
Jabbar AA, Mezaal TJ, Dawood FH. Association of HLA antigens with diabetes mellitus in an Iraqi population. Dis Markers. 1989;7(2):79-85.
Jabbar, A. A., Mezaal, T. J., & Dawood, F. H. (1989). Association of HLA antigens with diabetes mellitus in an Iraqi population. Disease Markers, 7(2), 79-85.
Jabbar AA, Mezaal TJ, Dawood FH. Association of HLA Antigens With Diabetes Mellitus in an Iraqi Population. Dis Markers. 1989 Apr-Jun;7(2):79-85. PubMed PMID: 2731409.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of HLA antigens with diabetes mellitus in an Iraqi population. AU - Jabbar,A A, AU - Mezaal,T J, AU - Dawood,F H, PY - 1989/4/1/pubmed PY - 1989/4/1/medline PY - 1989/4/1/entrez SP - 79 EP - 85 JF - Disease markers JO - Dis Markers VL - 7 IS - 2 N2 - HLA antigen frequencies in 50 patients with IDDM, 56 patients with NIDDM, and 109 normal Iraqi controls were studied. Three families with one patient suffering from IDDM were also studied. No significant HLA antigens associated with NIDDM were found. Highly significant association of HLA, A1, B8, DR3, and DR4 were found in patients with IDDM as compared to normal individuals. The frequency of HLA-B5 and DR2 were significantly decreased in patients with IDDM. In contrast to previously reported findings in Caucasoids there was no significant association with B15 and a negative association with HLA-B5, not with B7. These results were compared with published findings for Arabs and other ethnic populations. SN - 0278-0240 UR - https://www.unboundmedicine.com/medline/citation/2731409/Association_of_HLA_antigens_with_diabetes_mellitus_in_an_Iraqi_population_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -