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Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients with Benign Prostatic Hyperplasia: Results in 630 Patients.
J Vasc Interv Radiol. 2016 Aug; 27(8):1115-22.JV

Abstract

PURPOSE

To confirm that prostatic artery embolization (PAE) has a positive medium- and long-term effect in symptomatic benign prostatic hyperplasia (BPH).

MATERIALS AND METHODS

Between March 2009 and October 2014, 630 consecutive patients with BPH and moderate-to-severe lower urinary tract symptoms refractory to medical therapy for at least 6 months or who refused any medical therapy underwent PAE. Outcome parameters were evaluated at baseline; 1, 3, and 6 months; every 6 months between 1 and 3 years; and yearly thereafter up to 6.5 years.

RESULTS

Mean patient age was 65.1 years ± 8.0 (range, 40-89 y). There were 12 (1.9%) technical failures. Bilateral PAE was performed in 572 (92.6%) patients and unilateral PAE was performed in 46 (7.4%) patients. The cumulative clinical success rates at medium- and long-term follow-up were 81.9% (95% confidence interval [CI], 78.3%-84.9%) and 76.3% (95% CI, 68.6%-82.4%). There was a statistically significant (P < .0001) change from baseline to last observed value in all clinical parameters: International Prostate Symptom Score (IPSS), quality-of-life (QOL), prostate volume, prostate-specific antigen, urinary maximal flow rate, postvoid residual, and International Index of Erectile Function. There were 2 major complications without sequelae.

CONCLUSIONS

PAE had a positive effect on IPSS, QOL, and all objective outcomes in symptomatic BPH. The medium- (1-3 y) and long-term (> 3-6.5 y) clinical success rates were 81.9% and 76.3%, with no urinary incontinence or sexual dysfunction reported.

Authors+Show Affiliations

Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal; Department of Radiology, Nova Medical School, Lisbon, Portugal.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal; Department of Urology, Nova Medical School, Lisbon, Portugal.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal; Department of Radiology, Nova Medical School, Lisbon, Portugal.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal; Department of Radiology, Nova Medical School, Lisbon, Portugal.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal; Department of Radiology, Nova Medical School, Lisbon, Portugal. Electronic address: nunovpcosta@gmail.com.Interventional Radiology Department, Hospital Saint Louis, R. Luz Soriano, Lisbon 1200-249, Portugal.Department of Pharmacy, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27321890

Citation

Pisco, João M., et al. "Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients With Benign Prostatic Hyperplasia: Results in 630 Patients." Journal of Vascular and Interventional Radiology : JVIR, vol. 27, no. 8, 2016, pp. 1115-22.
Pisco JM, Bilhim T, Pinheiro LC, et al. Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients with Benign Prostatic Hyperplasia: Results in 630 Patients. J Vasc Interv Radiol. 2016;27(8):1115-22.
Pisco, J. M., Bilhim, T., Pinheiro, L. C., Fernandes, L., Pereira, J., Costa, N. V., Duarte, M., & Oliveira, A. G. (2016). Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients with Benign Prostatic Hyperplasia: Results in 630 Patients. Journal of Vascular and Interventional Radiology : JVIR, 27(8), 1115-22. https://doi.org/10.1016/j.jvir.2016.04.001
Pisco JM, et al. Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients With Benign Prostatic Hyperplasia: Results in 630 Patients. J Vasc Interv Radiol. 2016;27(8):1115-22. PubMed PMID: 27321890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients with Benign Prostatic Hyperplasia: Results in 630 Patients. AU - Pisco,João M, AU - Bilhim,Tiago, AU - Pinheiro,Luis C, AU - Fernandes,Lucia, AU - Pereira,Jose, AU - Costa,Nuno V, AU - Duarte,Marisa, AU - Oliveira,António G, Y1 - 2016/06/16/ PY - 2016/01/01/received PY - 2016/03/31/revised PY - 2016/04/01/accepted PY - 2016/6/21/entrez PY - 2016/6/21/pubmed PY - 2017/7/14/medline SP - 1115 EP - 22 JF - Journal of vascular and interventional radiology : JVIR JO - J Vasc Interv Radiol VL - 27 IS - 8 N2 - PURPOSE: To confirm that prostatic artery embolization (PAE) has a positive medium- and long-term effect in symptomatic benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Between March 2009 and October 2014, 630 consecutive patients with BPH and moderate-to-severe lower urinary tract symptoms refractory to medical therapy for at least 6 months or who refused any medical therapy underwent PAE. Outcome parameters were evaluated at baseline; 1, 3, and 6 months; every 6 months between 1 and 3 years; and yearly thereafter up to 6.5 years. RESULTS: Mean patient age was 65.1 years ± 8.0 (range, 40-89 y). There were 12 (1.9%) technical failures. Bilateral PAE was performed in 572 (92.6%) patients and unilateral PAE was performed in 46 (7.4%) patients. The cumulative clinical success rates at medium- and long-term follow-up were 81.9% (95% confidence interval [CI], 78.3%-84.9%) and 76.3% (95% CI, 68.6%-82.4%). There was a statistically significant (P < .0001) change from baseline to last observed value in all clinical parameters: International Prostate Symptom Score (IPSS), quality-of-life (QOL), prostate volume, prostate-specific antigen, urinary maximal flow rate, postvoid residual, and International Index of Erectile Function. There were 2 major complications without sequelae. CONCLUSIONS: PAE had a positive effect on IPSS, QOL, and all objective outcomes in symptomatic BPH. The medium- (1-3 y) and long-term (> 3-6.5 y) clinical success rates were 81.9% and 76.3%, with no urinary incontinence or sexual dysfunction reported. SN - 1535-7732 UR - https://www.unboundmedicine.com/medline/citation/27321890/Medium__and_Long_Term_Outcome_of_Prostate_Artery_Embolization_for_Patients_with_Benign_Prostatic_Hyperplasia:_Results_in_630_Patients_ DB - PRIME DP - Unbound Medicine ER -