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Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report.
Gynecol Oncol Rep 2016; 16:31-3GO

Abstract

Vulvar lymphangioma circumscriptum (LC) is a rare entity which may present as a painful, warty lesion. In contrast to the congenital form, which occurs in children, the acquired form arises in older adults and may be associated with infection, Crohn's disease, or prior pelvic/regional surgery. We present a case of acquired LC of the vulva in a 55-year-old woman who presented with a 3-4 year history of vulvar pain following chemotherapy, radiation, and brachytherapy for cervical cancer. Vulvar shave biopsies followed by excision revealed a thickened dermis with epidermal hyperkeratosis, parakeratosis, elongated rete ridges and dilated lymphatic channels containing eosinophilic material and scattered thrombi. The differential diagnosis for this unusual lesion includes more common conditions such as condyloma acuminatum, fungating squamous cell carcinoma and molluscum contagiosum. It is important to recognize the clinical presentation as well as the distinct histological appearance of this rare benign entity.

Authors+Show Affiliations

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

27331134

Citation

Valente, Kari, et al. "Acquired Vulvar Lymphangioma Circumscriptum After Cervical Cancer Treatment: Case Report." Gynecologic Oncology Reports, vol. 16, 2016, pp. 31-3.
Valente K, Montgomery K, Schultenover S, et al. Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report. Gynecol Oncol Rep. 2016;16:31-3.
Valente, K., Montgomery, K., Schultenover, S., & Desouki, M. M. (2016). Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report. Gynecologic Oncology Reports, 16, pp. 31-3. doi:10.1016/j.gore.2016.03.006.
Valente K, et al. Acquired Vulvar Lymphangioma Circumscriptum After Cervical Cancer Treatment: Case Report. Gynecol Oncol Rep. 2016;16:31-3. PubMed PMID: 27331134.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report. AU - Valente,Kari, AU - Montgomery,Kathleen, AU - Schultenover,Stephen, AU - Desouki,Mohamed Mokhtar, Y1 - 2016/04/01/ PY - 2016/02/07/received PY - 2016/03/10/revised PY - 2016/03/24/accepted PY - 2016/6/23/entrez PY - 2016/6/23/pubmed PY - 2016/6/23/medline KW - Cervical cancer KW - Genital wart KW - LC, lymphangioma circumscriptum KW - Lymphangioma circumscriptum KW - Lymphatics KW - Vulvar pain SP - 31 EP - 3 JF - Gynecologic oncology reports JO - Gynecol Oncol Rep VL - 16 N2 - Vulvar lymphangioma circumscriptum (LC) is a rare entity which may present as a painful, warty lesion. In contrast to the congenital form, which occurs in children, the acquired form arises in older adults and may be associated with infection, Crohn's disease, or prior pelvic/regional surgery. We present a case of acquired LC of the vulva in a 55-year-old woman who presented with a 3-4 year history of vulvar pain following chemotherapy, radiation, and brachytherapy for cervical cancer. Vulvar shave biopsies followed by excision revealed a thickened dermis with epidermal hyperkeratosis, parakeratosis, elongated rete ridges and dilated lymphatic channels containing eosinophilic material and scattered thrombi. The differential diagnosis for this unusual lesion includes more common conditions such as condyloma acuminatum, fungating squamous cell carcinoma and molluscum contagiosum. It is important to recognize the clinical presentation as well as the distinct histological appearance of this rare benign entity. SN - 2352-5789 UR - https://www.unboundmedicine.com/medline/citation/27331134/Acquired_vulvar_lymphangioma_circumscriptum_after_cervical_cancer_treatment:_Case_report_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S2352-5789(16)30014-5 DB - PRIME DP - Unbound Medicine ER -