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The Circulatory System in Liver Disease.
Crit Care Clin. 2016 Jul; 32(3):331-42.CC

Abstract

In the cirrhotic liver, distortion of the normal liver architecture is caused by structural and vascular changes. Portal hypertension is often associated with a hyperdynamic circulatory syndrome in which cardiac output and heart rate are increased and systemic vascular resistance is decreased. The release of several vasoactive substances is the primary factor involved in the reduction of mesenteric arterial resistance, resulting in sodium and water retention with eventual formation of ascites. Management of these patients with acute cardiac dysfunction often requires invasive hemodynamic monitoring in an intensive care unit setting to tailor decisions regarding use of fluids and vasopressors.

Authors+Show Affiliations

Department of Cardiovascular Disease, Cooper University Hospital, 1 Cooper Plaza, Camden, 08103, NJ, USA. Electronic address: hollenberg-steven@cooperhealth.edu.Department of Cardiovascular Disease, Cooper University Hospital, 1 Cooper Plaza, Camden, 08103, NJ, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27339674

Citation

Hollenberg, Steven M., and Brett Waldman. "The Circulatory System in Liver Disease." Critical Care Clinics, vol. 32, no. 3, 2016, pp. 331-42.
Hollenberg SM, Waldman B. The Circulatory System in Liver Disease. Crit Care Clin. 2016;32(3):331-42.
Hollenberg, S. M., & Waldman, B. (2016). The Circulatory System in Liver Disease. Critical Care Clinics, 32(3), 331-42. https://doi.org/10.1016/j.ccc.2016.02.004
Hollenberg SM, Waldman B. The Circulatory System in Liver Disease. Crit Care Clin. 2016;32(3):331-42. PubMed PMID: 27339674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Circulatory System in Liver Disease. AU - Hollenberg,Steven M, AU - Waldman,Brett, PY - 2016/6/25/entrez PY - 2016/6/25/pubmed PY - 2017/6/21/medline KW - Circulation KW - Cirrhosis KW - Liver disease KW - Vascular resistance SP - 331 EP - 42 JF - Critical care clinics JO - Crit Care Clin VL - 32 IS - 3 N2 - In the cirrhotic liver, distortion of the normal liver architecture is caused by structural and vascular changes. Portal hypertension is often associated with a hyperdynamic circulatory syndrome in which cardiac output and heart rate are increased and systemic vascular resistance is decreased. The release of several vasoactive substances is the primary factor involved in the reduction of mesenteric arterial resistance, resulting in sodium and water retention with eventual formation of ascites. Management of these patients with acute cardiac dysfunction often requires invasive hemodynamic monitoring in an intensive care unit setting to tailor decisions regarding use of fluids and vasopressors. SN - 1557-8232 UR - https://www.unboundmedicine.com/medline/citation/27339674/The_Circulatory_System_in_Liver_Disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0749-0704(16)30016-1 DB - PRIME DP - Unbound Medicine ER -