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[Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda].
Hautarzt. 2016 Sep; 67(9):712-7.H

Abstract

BACKGROUND

Tinea capitis is caused by anthropophilic, zoophilic or geophilic dermatophytes of the genera Microsporum or Trichophyton.

OBJECTIVE

The aim of this study was to analyze the clinical presentation of tinea capitis among children in western Uganda.

PATIENTS AND METHODS

From February to June 2012, skin and hair samples were obtained from 115 patients aged from 1 to 16 years presenting at Mbarara Regional Referral Hospital (MUSC) with clinically suspected tinea capitis. Conventional mycological diagnostics comprised Blancophor preparation and cultivation of fungi for species identification.

RESULTS

Tinea capitis among the children included in the MUSC study was mainly noninflammatory showing mostly a seborrhoeic pattern or "black dot" and "gray patch" form and highly inflammatory kerion celsi. Blancophor preparation identified 82.6 % positive and 17.4 % negative samples. Cultural species differentiation showed Trichophyton (T.) violaceum as the causative agent for tinea capitis in 56.6 % of the patients. In 13 %, Microsporum (M.) audouinii was isolated followed by T. soudanense (2.6 %), and T. rubrum (1.7 %). In addition, moulds (contamination?) such as Scopulariopsis brevicaulis, Aspergillus niger, and Fusarium oxysporum were found as well as mixed infections.

CONCLUSION

The anthropophilic dermatophyte T. violaceum represents the most frequent cause of tinea capitis in western Uganda. For successful management oral antifungal therapy is necessary together with supportive topical treatment.

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    • Authors+Show Affiliations

    Wiegand C
    Klinik für Hautkrankheiten, Universitätsklinikum Jena, Erfurter Str. 35, 07740, Jena, Deutschland. C.Wiegand@med.uni-jena.de.
    Mugisha P
    Klinik für Hautkrankheiten, Universitätsklinikum Jena, Erfurter Str. 35, 07740, Jena, Deutschland. Dept. of Dermatology, Mbarara University of Science and Technology, Mbarara, Uganda.
    Mulyowa GK
    Dept. of Dermatology, Mbarara University of Science and Technology, Mbarara, Uganda.
    Elsner P
    Klinik für Hautkrankheiten, Universitätsklinikum Jena, Erfurter Str. 35, 07740, Jena, Deutschland.
    Hipler UC
    Klinik für Hautkrankheiten, Universitätsklinikum Jena, Erfurter Str. 35, 07740, Jena, Deutschland.
    Gräser Y
    Konsiliarlabor für Dermatophyten, Institut für Mikrobiologie und Hygiene, Universitätsmedizin Berlin-Charité, Berlin, Deutschland.
    Uhrlaβ S
    Labor für medizinische Mikrobiologie, Mölbis, Deutschland.
    Nenoff P
    Labor für medizinische Mikrobiologie, Mölbis, Deutschland.

    MeSH

    AdolescentChildChild, PreschoolFemaleHospitals, CommunityHumansIncidenceInfantMalePrevalenceReferral and ConsultationRisk FactorsSpecies SpecificityTineaTinea CapitisTreatment OutcomeTrichophytonUganda

    Pub Type(s)

    Journal Article
    Review

    Language

    ger

    PubMed ID

    27341825

    Citation

    Wiegand, C, et al. "[Trichophyton Violaceum : Main Cause of Tinea Capitis in Children at Mbarara Regional Referral Hospital in Uganda]." Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, vol. 67, no. 9, 2016, pp. 712-7.
    Wiegand C, Mugisha P, Mulyowa GK, et al. [Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]. Hautarzt. 2016;67(9):712-7.
    Wiegand, C., Mugisha, P., Mulyowa, G. K., Elsner, P., Hipler, U. C., Gräser, Y., Uhrlaβ, S., & Nenoff, P. (2016). [Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, 67(9), 712-7. https://doi.org/10.1007/s00105-016-3831-1
    Wiegand C, et al. [Trichophyton Violaceum : Main Cause of Tinea Capitis in Children at Mbarara Regional Referral Hospital in Uganda]. Hautarzt. 2016;67(9):712-7. PubMed PMID: 27341825.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - [Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]. AU - Wiegand,C, AU - Mugisha,P, AU - Mulyowa,G K, AU - Elsner,P, AU - Hipler,U C, AU - Gräser,Y, AU - Uhrlaβ,S, AU - Nenoff,P, PY - 2016/6/26/entrez PY - 2016/6/28/pubmed PY - 2017/5/24/medline KW - Dermatophytes KW - Fungi KW - Kerion celsi KW - Microsporum audouinii KW - Therapy SP - 712 EP - 7 JF - Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete JO - Hautarzt VL - 67 IS - 9 N2 - BACKGROUND: Tinea capitis is caused by anthropophilic, zoophilic or geophilic dermatophytes of the genera Microsporum or Trichophyton. OBJECTIVE: The aim of this study was to analyze the clinical presentation of tinea capitis among children in western Uganda. PATIENTS AND METHODS: From February to June 2012, skin and hair samples were obtained from 115 patients aged from 1 to 16 years presenting at Mbarara Regional Referral Hospital (MUSC) with clinically suspected tinea capitis. Conventional mycological diagnostics comprised Blancophor preparation and cultivation of fungi for species identification. RESULTS: Tinea capitis among the children included in the MUSC study was mainly noninflammatory showing mostly a seborrhoeic pattern or "black dot" and "gray patch" form and highly inflammatory kerion celsi. Blancophor preparation identified 82.6 % positive and 17.4 % negative samples. Cultural species differentiation showed Trichophyton (T.) violaceum as the causative agent for tinea capitis in 56.6 % of the patients. In 13 %, Microsporum (M.) audouinii was isolated followed by T. soudanense (2.6 %), and T. rubrum (1.7 %). In addition, moulds (contamination?) such as Scopulariopsis brevicaulis, Aspergillus niger, and Fusarium oxysporum were found as well as mixed infections. CONCLUSION: The anthropophilic dermatophyte T. violaceum represents the most frequent cause of tinea capitis in western Uganda. For successful management oral antifungal therapy is necessary together with supportive topical treatment. SN - 1432-1173 UR - https://www.unboundmedicine.com/medline/citation/27341825/[Trichophyton_violaceum_:_Main_cause_of_tinea_capitis_in_children_at_Mbarara_Regional_Referral_Hospital_in_Uganda]_ L2 - https://dx.doi.org/10.1007/s00105-016-3831-1 DB - PRIME DP - Unbound Medicine ER -