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PFAPA syndrome: a review on treatment and outcome.
Pediatr Rheumatol Online J. 2016 Jun 27; 14(1):38.PR

Abstract

The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA syndrome) is the most common cause of periodic fever in childhood. The current pharmacological treatment includes corticosteroids, which usually are efficacious in the management of fever episodes, colchicine, for the prophylaxis of febrile episodes, and other medication for which efficacy has not been proven so far. Tonsillectomy is an option for selected patients. Usually PFAPA syndrome resolves during adolescence, but there is increasing evidence that this condition may persist into adulthood.

Authors+Show Affiliations

Pediatric Department of Southern Switzerland, Ospedale Regionale di Bellinzona e Valli, Bellinzona, 6500, Switzerland. federica.vanoni@eoc.ch.Unité Romande d'Immuno-rhumatologie Pédiatrique (URIRP), Département Femme-Mère-Enfant (DFME), CHUV, University of Lausanne, Rue du Bugnon 46, Lausanne, 1011, Switzerland.Unité Romande d'Immuno-rhumatologie Pédiatrique (URIRP), Département Médico - Chirurgical de Pédiatrie (DFME), CHUV, University of Lausanne, Rue du Bugnon 46, Lausanne, 1011, Switzerland.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27349388

Citation

Vanoni, Federica, et al. "PFAPA Syndrome: a Review On Treatment and Outcome." Pediatric Rheumatology Online Journal, vol. 14, no. 1, 2016, p. 38.
Vanoni F, Theodoropoulou K, Hofer M. PFAPA syndrome: a review on treatment and outcome. Pediatr Rheumatol Online J. 2016;14(1):38.
Vanoni, F., Theodoropoulou, K., & Hofer, M. (2016). PFAPA syndrome: a review on treatment and outcome. Pediatric Rheumatology Online Journal, 14(1), 38. https://doi.org/10.1186/s12969-016-0101-9
Vanoni F, Theodoropoulou K, Hofer M. PFAPA Syndrome: a Review On Treatment and Outcome. Pediatr Rheumatol Online J. 2016 Jun 27;14(1):38. PubMed PMID: 27349388.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - PFAPA syndrome: a review on treatment and outcome. AU - Vanoni,Federica, AU - Theodoropoulou,Katerina, AU - Hofer,Michaël, Y1 - 2016/06/27/ PY - 2016/04/08/received PY - 2016/06/21/accepted PY - 2016/6/29/entrez PY - 2016/6/29/pubmed PY - 2017/3/23/medline KW - Colchicine KW - Glucocorticoids KW - PFAPA outcome KW - PFAPA treatment KW - Tonsillectomy SP - 38 EP - 38 JF - Pediatric rheumatology online journal JO - Pediatr Rheumatol Online J VL - 14 IS - 1 N2 - The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA syndrome) is the most common cause of periodic fever in childhood. The current pharmacological treatment includes corticosteroids, which usually are efficacious in the management of fever episodes, colchicine, for the prophylaxis of febrile episodes, and other medication for which efficacy has not been proven so far. Tonsillectomy is an option for selected patients. Usually PFAPA syndrome resolves during adolescence, but there is increasing evidence that this condition may persist into adulthood. SN - 1546-0096 UR - https://www.unboundmedicine.com/medline/citation/27349388/PFAPA_syndrome:_a_review_on_treatment_and_outcome_ L2 - https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-016-0101-9 DB - PRIME DP - Unbound Medicine ER -