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Primary Leptomeningeal PNETs Mimicking TB Meningitis: A Case Report and Literature Review.
Turk Neurosurg. 2017; 27(1):155-159.TN

Abstract

Primitive neuroectodermal tumors (PNETs) are easily detected, and the diagnosis made by neuroradiologic imaging. Leptomeningeal seeding is a common complication and carries a poor prognosis. Primary leptomeningeal PNETs are rarer and difficult to diagnose on magnetic resonance imaging (MRI) or cerebrospinal fluid (CSF) studies. We encountered a rare case of primary leptomeningeal primitive neuroectodermal tumor without intracranial mass lesion which was diagnosed by spinal lesion biopsy. This 25-year-old woman presented with worsening headaches and progressive visual impairment.The initial diagnosis was tubercle bacillus (TB) meningitis, and the final diagnosis of primary leptomeningeal PNET was made by spinal biopsy. We present this illustrative case, review previous cases in the literature, and suggest that diagnosis is considered in mildly affected patients with similar symptoms.

Authors+Show Affiliations

China Medical University Hospital, Department of Neurosurgery, Taichung, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

27349395

Citation

Hsiao, I-Han, et al. "Primary Leptomeningeal PNETs Mimicking TB Meningitis: a Case Report and Literature Review." Turkish Neurosurgery, vol. 27, no. 1, 2017, pp. 155-159.
Hsiao IH, Chen CH, Lee HC, et al. Primary Leptomeningeal PNETs Mimicking TB Meningitis: A Case Report and Literature Review. Turk Neurosurg. 2017;27(1):155-159.
Hsiao, I. H., Chen, C. H., Lee, H. C., & Cho, D. Y. (2017). Primary Leptomeningeal PNETs Mimicking TB Meningitis: A Case Report and Literature Review. Turkish Neurosurgery, 27(1), 155-159. https://doi.org/10.5137/1019-5149.JTN.12123-14.2
Hsiao IH, et al. Primary Leptomeningeal PNETs Mimicking TB Meningitis: a Case Report and Literature Review. Turk Neurosurg. 2017;27(1):155-159. PubMed PMID: 27349395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primary Leptomeningeal PNETs Mimicking TB Meningitis: A Case Report and Literature Review. AU - Hsiao,I-Han, AU - Chen,Chao-Hsuan, AU - Lee,Han-Chung, AU - Cho,Der-Yang, PY - 2014/10/31/pubmed PY - 2017/4/7/medline PY - 2016/6/29/entrez SP - 155 EP - 159 JF - Turkish neurosurgery JO - Turk Neurosurg VL - 27 IS - 1 N2 - Primitive neuroectodermal tumors (PNETs) are easily detected, and the diagnosis made by neuroradiologic imaging. Leptomeningeal seeding is a common complication and carries a poor prognosis. Primary leptomeningeal PNETs are rarer and difficult to diagnose on magnetic resonance imaging (MRI) or cerebrospinal fluid (CSF) studies. We encountered a rare case of primary leptomeningeal primitive neuroectodermal tumor without intracranial mass lesion which was diagnosed by spinal lesion biopsy. This 25-year-old woman presented with worsening headaches and progressive visual impairment.The initial diagnosis was tubercle bacillus (TB) meningitis, and the final diagnosis of primary leptomeningeal PNET was made by spinal biopsy. We present this illustrative case, review previous cases in the literature, and suggest that diagnosis is considered in mildly affected patients with similar symptoms. SN - 1019-5149 UR - https://www.unboundmedicine.com/medline/citation/27349395/Primary_Leptomeningeal_PNETs_Mimicking_TB_Meningitis:_A_Case_Report_and_Literature_Review_ L2 - http://www.turkishneurosurgery.org.tr/pubmed.php3?year=2017&volume=27&issue=1&page=155 DB - PRIME DP - Unbound Medicine ER -