Tags

Type your tag names separated by a space and hit enter

Dengue in Peace Corps Volunteers, 2000-14.
J Travel Med. 2016 Mar; 23(3)JT

Abstract

BACKGROUND

Dengue is an arboviral disease estimated to cause 50-100 million infections each year in >100 tropical and subtropical countries. Urbanization, human population growth and expanded global travel have resulted in an increase in the incidence of dengue worldwide. International travellers to areas with endemic dengue are at risk of contracting dengue and US Peace Corps Volunteers are one specific group of long-term travellers who are exposed to environments where dengue can be contracted.

METHODS

Cases of dengue among Peace Corps Volunteers, defined as clinically apparent infections with laboratory-confirmation by a positive NS1 antigen test, demonstration of IgM antibodies or by a 4-fold increase in IgG antibodies, between 1 January 2000 and 31 December 2014, reported to the Peace Corps’ Epidemiologic Surveillance System were analyzed.

RESULTS

Overall there were 1448 cases of dengue reported among Volunteers, with an incidence rate of 1.12 cases per 1000 Volunteer-months (95% CI 1.06-1.17). The highest rate of dengue among Volunteers was reported in the Caribbean region, with a rate of 5.51 cases per 1000 Volunteer-months (95% CI 4.97-6.10), followed by the East Asia/South Asia region (3.34, 95% CI 2.96-3.75) and Central America (2.55, 95% CI 2.32-2.79). The rate of dengue peaked in 2007, 2010 and 2013. Each peak year was followed by a trough year.

CONCLUSIONS

Globally, there appears to be a 3-year cyclical pattern of dengue incidence among Volunteers, with differences by region. Dengue continues to be a priority health issue for travellers to endemic areas, and enhanced surveillance of dengue among international travellers may result in improved patient education and prevention efforts.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

27356308

Citation

Ferguson, Rennie W., et al. "Dengue in Peace Corps Volunteers, 2000-14." Journal of Travel Medicine, vol. 23, no. 3, 2016.
Ferguson RW, Henderson SJ, Lee EA, et al. Dengue in Peace Corps Volunteers, 2000-14. J Travel Med. 2016;23(3).
Ferguson, R. W., Henderson, S. J., Lee, E. A., & Jung, P. (2016). Dengue in Peace Corps Volunteers, 2000-14. Journal of Travel Medicine, 23(3). https://doi.org/10.1093/jtm/taw010
Ferguson RW, et al. Dengue in Peace Corps Volunteers, 2000-14. J Travel Med. 2016;23(3) PubMed PMID: 27356308.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dengue in Peace Corps Volunteers, 2000-14. AU - Ferguson,Rennie W, AU - Henderson,Susan J, AU - Lee,E Avery, AU - Jung,Paul, PY - 2016/7/1/entrez PY - 2016/7/1/pubmed PY - 2016/12/15/medline JF - Journal of travel medicine JO - J Travel Med VL - 23 IS - 3 N2 - BACKGROUND: Dengue is an arboviral disease estimated to cause 50-100 million infections each year in >100 tropical and subtropical countries. Urbanization, human population growth and expanded global travel have resulted in an increase in the incidence of dengue worldwide. International travellers to areas with endemic dengue are at risk of contracting dengue and US Peace Corps Volunteers are one specific group of long-term travellers who are exposed to environments where dengue can be contracted. METHODS: Cases of dengue among Peace Corps Volunteers, defined as clinically apparent infections with laboratory-confirmation by a positive NS1 antigen test, demonstration of IgM antibodies or by a 4-fold increase in IgG antibodies, between 1 January 2000 and 31 December 2014, reported to the Peace Corps’ Epidemiologic Surveillance System were analyzed. RESULTS: Overall there were 1448 cases of dengue reported among Volunteers, with an incidence rate of 1.12 cases per 1000 Volunteer-months (95% CI 1.06-1.17). The highest rate of dengue among Volunteers was reported in the Caribbean region, with a rate of 5.51 cases per 1000 Volunteer-months (95% CI 4.97-6.10), followed by the East Asia/South Asia region (3.34, 95% CI 2.96-3.75) and Central America (2.55, 95% CI 2.32-2.79). The rate of dengue peaked in 2007, 2010 and 2013. Each peak year was followed by a trough year. CONCLUSIONS: Globally, there appears to be a 3-year cyclical pattern of dengue incidence among Volunteers, with differences by region. Dengue continues to be a priority health issue for travellers to endemic areas, and enhanced surveillance of dengue among international travellers may result in improved patient education and prevention efforts. SN - 1708-8305 UR - https://www.unboundmedicine.com/medline/citation/27356308/Dengue_in_Peace_Corps_Volunteers_2000_14_ L2 - https://academic.oup.com/jtm/article-lookup/doi/10.1093/jtm/taw010 DB - PRIME DP - Unbound Medicine ER -