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The Pathology of Alcoholic Liver Disease.
Clin Liver Dis. 2016 Aug; 20(3):473-89.CL

Abstract

The term "alcoholic liver disease" encompasses a spectrum of pathologic conditions ranging from isolated steatosis to established cirrhosis. Within this spectrum, varying degrees of inflammation, hepatocellular ballooning degeneration, hepatocyte necrosis, cholestasis, and fibrosis may be encountered. This article reviews the characteristic histologic features of the many forms of alcoholic liver disease. Histologic scoring systems are described, and diseases with overlapping morphologic features and comorbid conditions are also discussed.

Authors+Show Affiliations

Department of Pathology, The University of Chicago, 5841 South Maryland Avenue, MC 6101, Chicago, IL 60637, USA. Electronic address: Lindsay.Alpert@uchospitals.edu.Department of Pathology, The University of Chicago, 5841 South Maryland Avenue, MC 6101, Chicago, IL 60637, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27373610

Citation

Alpert, Lindsay, and John Hart. "The Pathology of Alcoholic Liver Disease." Clinics in Liver Disease, vol. 20, no. 3, 2016, pp. 473-89.
Alpert L, Hart J. The Pathology of Alcoholic Liver Disease. Clin Liver Dis. 2016;20(3):473-89.
Alpert, L., & Hart, J. (2016). The Pathology of Alcoholic Liver Disease. Clinics in Liver Disease, 20(3), 473-89. https://doi.org/10.1016/j.cld.2016.02.006
Alpert L, Hart J. The Pathology of Alcoholic Liver Disease. Clin Liver Dis. 2016;20(3):473-89. PubMed PMID: 27373610.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Pathology of Alcoholic Liver Disease. AU - Alpert,Lindsay, AU - Hart,John, Y1 - 2016/04/09/ PY - 2016/7/5/entrez PY - 2016/7/5/pubmed PY - 2017/9/19/medline KW - Alcoholic steatohepatitis KW - Ballooning degeneration KW - Cholestasis KW - Cirrhosis KW - Sinusoidal fibrosis KW - Steatosis SP - 473 EP - 89 JF - Clinics in liver disease JO - Clin Liver Dis VL - 20 IS - 3 N2 - The term "alcoholic liver disease" encompasses a spectrum of pathologic conditions ranging from isolated steatosis to established cirrhosis. Within this spectrum, varying degrees of inflammation, hepatocellular ballooning degeneration, hepatocyte necrosis, cholestasis, and fibrosis may be encountered. This article reviews the characteristic histologic features of the many forms of alcoholic liver disease. Histologic scoring systems are described, and diseases with overlapping morphologic features and comorbid conditions are also discussed. SN - 1557-8224 UR - https://www.unboundmedicine.com/medline/citation/27373610/The_Pathology_of_Alcoholic_Liver_Disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1089-3261(16)30006-X DB - PRIME DP - Unbound Medicine ER -