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Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp.
Chem Pharm Bull (Tokyo). 2016; 64(7):975-8.CP

Abstract

New bisindole alkaloids, hyrtinadines C (1) and D (2), have been isolated from an Okinawan marine sponge Hyrtios sp. The structures of hyrtinadines C (1) and D (2) were elucidated based on analyses of the spectral data. Hyrtinadines C (1) and D (2) were the relatively rare alkaloids possessing a 3,4-fused azepinoindole skeleton. Hyrtinadines C (1) and D (2) showed antimicrobial activity.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Kubota T
Showa Pharmaceutical University.
Nakamura K
No affiliation info available
Sakai K
No affiliation info available
Fromont J
No affiliation info available
Gonoi T
No affiliation info available
Kobayashi J
No affiliation info available

MeSH

AnimalsAnti-Bacterial AgentsAntifungal AgentsAspergillus nigerBacillus subtilisCandida albicansCryptococcus neoformansDose-Response Relationship, DrugEscherichia coliIndole AlkaloidsMicrobial Sensitivity TestsMicrococcus luteusMolecular StructurePoriferaStaphylococcus aureusStructure-Activity RelationshipTrichophyton

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27373657

Citation

Kubota, Takaaki, et al. "Hyrtinadines C and D, New Azepinoindole-Type Alkaloids From a Marine Sponge Hyrtios Sp." Chemical & Pharmaceutical Bulletin, vol. 64, no. 7, 2016, pp. 975-8.
Kubota T, Nakamura K, Sakai K, et al. Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp. Chem Pharm Bull (Tokyo). 2016;64(7):975-8.
Kubota, T., Nakamura, K., Sakai, K., Fromont, J., Gonoi, T., & Kobayashi, J. (2016). Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp. Chemical & Pharmaceutical Bulletin, 64(7), 975-8. https://doi.org/10.1248/cpb.c16-00201
Kubota T, et al. Hyrtinadines C and D, New Azepinoindole-Type Alkaloids From a Marine Sponge Hyrtios Sp. Chem Pharm Bull (Tokyo). 2016;64(7):975-8. PubMed PMID: 27373657.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp. AU - Kubota,Takaaki, AU - Nakamura,Kenta, AU - Sakai,Kanae, AU - Fromont,Jane, AU - Gonoi,Tohru, AU - Kobayashi,Jun'ichi, PY - 2016/7/5/entrez PY - 2016/7/5/pubmed PY - 2017/1/27/medline SP - 975 EP - 8 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 64 IS - 7 N2 - New bisindole alkaloids, hyrtinadines C (1) and D (2), have been isolated from an Okinawan marine sponge Hyrtios sp. The structures of hyrtinadines C (1) and D (2) were elucidated based on analyses of the spectral data. Hyrtinadines C (1) and D (2) were the relatively rare alkaloids possessing a 3,4-fused azepinoindole skeleton. Hyrtinadines C (1) and D (2) showed antimicrobial activity. SN - 1347-5223 UR - https://www.unboundmedicine.com/medline/citation/27373657/Hyrtinadines_C_and_D_New_Azepinoindole_Type_Alkaloids_from_a_Marine_Sponge_Hyrtios_sp_ DB - PRIME DP - Unbound Medicine ER -