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FDG-PET hyperactivity pattern in anti-NMDAr encephalitis.
J Neuroimmunol. 2016 08 15; 297:156-8.JN

Abstract

FDG-PET can show anteroposterior glucose metabolism gradient in anti-NMDAr encephalitis, but there are also suggestions that basal ganglia are involved. We examined FDG-PET scans in 5 consecutive episodes of serologically proven anti-NMDAr encephalitis, compared with healthy controls. We confirmed the anteroposterior metabolic gradient and found a significant FDG uptake increase in the caudate nuclei in episodes of varying intensity and delay from the onset of the symptoms. FDG-PET can be useful in the work-up of suspected anti-NMDAr encephalitis disclosing a characteristic cortical and sub-cortical metabolism pattern.

Authors+Show Affiliations

Neurology service, Department of clinical neurosciences, CHUV, University of Lausanne, Lausanne, Switzerland. Electronic address: jan.novy@chuv.ch.Nuclear Medicine, CHUV, University of Lausanne, Lausanne, Switzerland.Department of Epileptology, University of Bonn, Bonn, Germany; Epilepsy Centre Bethel, Mara Hospital, Bielefeld, Germany.Service Central de Biophysique et Médecine Nucléaire, CHU Timone & Centre Européen de Recherche en Imagerie Médicale, CERIMED & Centre d'Investigation Clinique, CIC, INSERM, Université de la Méditerranée, Marseille F-13000, France.Nuclear Medicine, CHUV, University of Lausanne, Lausanne, Switzerland.Neurology service, Department of clinical neurosciences, CHUV, University of Lausanne, Lausanne, Switzerland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27397089

Citation

Novy, Jan, et al. "FDG-PET Hyperactivity Pattern in anti-NMDAr Encephalitis." Journal of Neuroimmunology, vol. 297, 2016, pp. 156-8.
Novy J, Allenbach G, Bien CG, et al. FDG-PET hyperactivity pattern in anti-NMDAr encephalitis. J Neuroimmunol. 2016;297:156-8.
Novy, J., Allenbach, G., Bien, C. G., Guedj, E., Prior, J. O., & Rossetti, A. O. (2016). FDG-PET hyperactivity pattern in anti-NMDAr encephalitis. Journal of Neuroimmunology, 297, 156-8. https://doi.org/10.1016/j.jneuroim.2016.05.016
Novy J, et al. FDG-PET Hyperactivity Pattern in anti-NMDAr Encephalitis. J Neuroimmunol. 2016 08 15;297:156-8. PubMed PMID: 27397089.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - FDG-PET hyperactivity pattern in anti-NMDAr encephalitis. AU - Novy,Jan, AU - Allenbach,Gilles, AU - Bien,Christian G, AU - Guedj,Eric, AU - Prior,John O, AU - Rossetti,Andrea O, Y1 - 2016/06/02/ PY - 2015/12/15/received PY - 2016/04/30/revised PY - 2016/05/22/accepted PY - 2016/7/12/entrez PY - 2016/7/12/pubmed PY - 2017/8/18/medline KW - Inflammation KW - NMDA KW - Psychiatry SP - 156 EP - 8 JF - Journal of neuroimmunology JO - J Neuroimmunol VL - 297 N2 - FDG-PET can show anteroposterior glucose metabolism gradient in anti-NMDAr encephalitis, but there are also suggestions that basal ganglia are involved. We examined FDG-PET scans in 5 consecutive episodes of serologically proven anti-NMDAr encephalitis, compared with healthy controls. We confirmed the anteroposterior metabolic gradient and found a significant FDG uptake increase in the caudate nuclei in episodes of varying intensity and delay from the onset of the symptoms. FDG-PET can be useful in the work-up of suspected anti-NMDAr encephalitis disclosing a characteristic cortical and sub-cortical metabolism pattern. SN - 1872-8421 UR - https://www.unboundmedicine.com/medline/citation/27397089/FDG_PET_hyperactivity_pattern_in_anti_NMDAr_encephalitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-5728(16)30125-4 DB - PRIME DP - Unbound Medicine ER -