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Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle.
Radiol Case Rep. 2015; 10(1):827.RC

Abstract

Zollinger-Ellison syndrome is a complex condition in which one or more tumors form in the patient's pancreas or upper duodenum. These tumors, called gastrinomas, secrete excessive amounts of gastrin, and almost all develop ulcers. The vast majority of gastrinomas are present within the "gastrinoma triangle," which is composed of the porta hepatis, duodenal sweep, and pancreatic head. As surgery remains the treatment of choice, localization of the primary lesion is often challenging but essential. We present a 50-year-old man with a tentative diagnosis of Zollinger-Ellison syndrome. His In-111 pentetreotide scan, fused onto a Tc-99m abdomen image, revealed an avid lesion adjacent to the duodenal loop. Operative resection was performed, and a primary pancreatic gastrinoma was diagnosed by immunohistochemical staining. The neuroendocrine tumors have somatostatin receptors upon them. Therefore, a penteteotide scan, using In-111 radiolabelled somatostatin analogues, is the current technique of choice. This dual-isotope display permits a visual perception of anatomic landmarks around the lesion.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports

Language

eng

PubMed ID

27408649

Citation

Yang, Rong-Hsin, and Yum-Kung Chu. "Zollinger-Ellison Syndrome: Revelation of the Gastrinoma Triangle." Radiology Case Reports, vol. 10, no. 1, 2015, p. 827.
Yang RH, Chu YK. Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle. Radiol Case Rep. 2015;10(1):827.
Yang, R. H., & Chu, Y. K. (2015). Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle. Radiology Case Reports, 10(1), 827. https://doi.org/10.2484/rcr.v10i1.827
Yang RH, Chu YK. Zollinger-Ellison Syndrome: Revelation of the Gastrinoma Triangle. Radiol Case Rep. 2015;10(1):827. PubMed PMID: 27408649.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle. AU - Yang,Rong-Hsin, AU - Chu,Yum-Kung, Y1 - 2015/12/03/ PY - 2016/7/14/entrez PY - 2015/1/1/pubmed PY - 2015/1/1/medline SP - 827 EP - 827 JF - Radiology case reports JO - Radiol Case Rep VL - 10 IS - 1 N2 - Zollinger-Ellison syndrome is a complex condition in which one or more tumors form in the patient's pancreas or upper duodenum. These tumors, called gastrinomas, secrete excessive amounts of gastrin, and almost all develop ulcers. The vast majority of gastrinomas are present within the "gastrinoma triangle," which is composed of the porta hepatis, duodenal sweep, and pancreatic head. As surgery remains the treatment of choice, localization of the primary lesion is often challenging but essential. We present a 50-year-old man with a tentative diagnosis of Zollinger-Ellison syndrome. His In-111 pentetreotide scan, fused onto a Tc-99m abdomen image, revealed an avid lesion adjacent to the duodenal loop. Operative resection was performed, and a primary pancreatic gastrinoma was diagnosed by immunohistochemical staining. The neuroendocrine tumors have somatostatin receptors upon them. Therefore, a penteteotide scan, using In-111 radiolabelled somatostatin analogues, is the current technique of choice. This dual-isotope display permits a visual perception of anatomic landmarks around the lesion. SN - 1930-0433 UR - https://www.unboundmedicine.com/medline/citation/27408649/Zollinger_Ellison_syndrome:_Revelation_of_the_gastrinoma_triangle_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1930-0433(15)30528-8 DB - PRIME DP - Unbound Medicine ER -
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