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Multiple eschars in scrub typhus: a case report.
Trop Doct. 2017 Jan; 47(1):67-69.TD

Abstract

Eschar in scrub typhus aids in early diagnosis and institution of appropriate therapy; however, the eschar positivity rates vary greatly in endemic regions. Multiple eschars in scrub typhus are a rare presentation. Our patient presented with fever and multiple eschars and was empirically started on doxycycline. Nested polymerase chain reaction from all the four eschars and from EDTA blood were positive for 56-kDa type-specific antigen which is specific for Orientia tsutsugamushi The patient recovered completely after 7 days of antibiotic treatment. He was from an area where scrub typhus was not observed previously. An eschar in an acute febrile patient from the "tsutsugamushi triangle" is a valuable sign in scrub typhus diagnosis. A search for multiple eschars in scrub typhus must be made by clinicians.

Authors+Show Affiliations

Lecturer, Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.Intern, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.Professor and Head, Department of Microbiology, MMMC, Manipal Campus, Manipal University, Manipal, Karnataka, India.Professor and Unit Head, Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.Professor and Unit Head, Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India drmuralidharvarma@yahoo.co.in.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27411364

Citation

Koraluru, Munegowda, et al. "Multiple Eschars in Scrub Typhus: a Case Report." Tropical Doctor, vol. 47, no. 1, 2017, pp. 67-69.
Koraluru M, Nandigam M, Bairy I, et al. Multiple eschars in scrub typhus: a case report. Trop Doct. 2017;47(1):67-69.
Koraluru, M., Nandigam, M., Bairy, I., Vidyasagar, S., & Varma, M. (2017). Multiple eschars in scrub typhus: a case report. Tropical Doctor, 47(1), 67-69.
Koraluru M, et al. Multiple Eschars in Scrub Typhus: a Case Report. Trop Doct. 2017;47(1):67-69. PubMed PMID: 27411364.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multiple eschars in scrub typhus: a case report. AU - Koraluru,Munegowda, AU - Nandigam,Manideep, AU - Bairy,Indira, AU - Vidyasagar,Sudha, AU - Varma,Muralidhar, Y1 - 2016/07/13/ PY - 2016/7/15/pubmed PY - 2017/4/28/medline PY - 2016/7/15/entrez KW - Doxycycline KW - Scrub typhus KW - multiple eschars KW - polymerase chain reaction (PCR) SP - 67 EP - 69 JF - Tropical doctor JO - Trop Doct VL - 47 IS - 1 N2 - Eschar in scrub typhus aids in early diagnosis and institution of appropriate therapy; however, the eschar positivity rates vary greatly in endemic regions. Multiple eschars in scrub typhus are a rare presentation. Our patient presented with fever and multiple eschars and was empirically started on doxycycline. Nested polymerase chain reaction from all the four eschars and from EDTA blood were positive for 56-kDa type-specific antigen which is specific for Orientia tsutsugamushi The patient recovered completely after 7 days of antibiotic treatment. He was from an area where scrub typhus was not observed previously. An eschar in an acute febrile patient from the "tsutsugamushi triangle" is a valuable sign in scrub typhus diagnosis. A search for multiple eschars in scrub typhus must be made by clinicians. SN - 1758-1133 UR - https://www.unboundmedicine.com/medline/citation/27411364/Multiple_eschars_in_scrub_typhus:_a_case_report_ L2 - https://journals.sagepub.com/doi/10.1177/0049475516658400?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -