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Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study.
Public Health Nutr 2017; 20(1):82-91PH

Abstract

OBJECTIVE

To test the association between coffee consumption and risk of all-cause, CVD and cancer death in a European cohort.

DESIGN

Prospective cohort study. Cox proportional hazards models with adjustment for potential confounders to estimate multivariable hazard ratios (HR) and 95 % CI were used.

SETTING

Czech Republic, Russia and Poland.

SUBJECTS

A total of 28561 individuals followed for 6·1 years.

RESULTS

A total of 2121 deaths (43·1 % CVD and 35·7 % cancer mortality) occurred during the follow-up. Consumption of 3-4 cups coffee/d was associated with lower mortality risk in men (HR=0·83; 95 % CI 0·71, 0·99) and women (HR=0·63; 95 % CI 0·47, 0·84), while further intake showed non-significant reduced risk estimates (HR=0·71; 95 % CI 0·49, 1·04 and HR=0·51; 95 % CI 0·24, 1·10 in men and women, respectively). Decreased risk of CVD mortality was also found in men (HR=0·71; 95 % CI 0·54, 0·93) for consumption of 3-4 cups coffee/d. Stratified analysis revealed that consumption of a similar amount of coffee was associated with decreased risk of all-cause (HR=0·61; 95 % CI 0·43, 0·87) and cancer mortality (HR=0·59; 95 % CI 0·35, 0·99) in non-smoking women and decreased risk of all-cause mortality for >4 cups coffee/d in men with no/moderate alcohol intake.

CONCLUSIONS

Coffee consumption was associated with decreased risk of mortality. The protective effect was even stronger when stratification by smoking status and alcohol intake was performed.

Authors+Show Affiliations

1Integrated Cancer Registry of Catania-Messina-Siracusa-Enna,Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele,Via S. Sofia 85,95123 Catania,Italy.2Department of Epidemiology and Population Studies,Jagiellonian University Medical College,Krakow,Poland.2Department of Epidemiology and Population Studies,Jagiellonian University Medical College,Krakow,Poland.3Department of Epidemiology and Public Health,University College London,London,UK.3Department of Epidemiology and Public Health,University College London,London,UK.2Department of Epidemiology and Population Studies,Jagiellonian University Medical College,Krakow,Poland.

Pub Type(s)

Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

27411779

Citation

Grosso, Giuseppe, et al. "Coffee Consumption and Mortality in Three Eastern European Countries: Results From the HAPIEE (Health, Alcohol and Psychosocial Factors in Eastern Europe) Study." Public Health Nutrition, vol. 20, no. 1, 2017, pp. 82-91.
Grosso G, Stepaniak U, Micek A, et al. Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study. Public Health Nutr. 2017;20(1):82-91.
Grosso, G., Stepaniak, U., Micek, A., Stefler, D., Bobak, M., & Pajak, A. (2017). Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study. Public Health Nutrition, 20(1), pp. 82-91. doi:10.1017/S1368980016001749.
Grosso G, et al. Coffee Consumption and Mortality in Three Eastern European Countries: Results From the HAPIEE (Health, Alcohol and Psychosocial Factors in Eastern Europe) Study. Public Health Nutr. 2017;20(1):82-91. PubMed PMID: 27411779.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study. AU - Grosso,Giuseppe, AU - Stepaniak,Urszula, AU - Micek,Agnieszka, AU - Stefler,Denes, AU - Bobak,Martin, AU - Pajak,Andrzej, Y1 - 2016/07/14/ PY - 2016/7/15/pubmed PY - 2018/2/27/medline PY - 2016/7/15/entrez KW - Coffee KW - Cohort KW - Europe KW - Mortality KW - Prospective SP - 82 EP - 91 JF - Public health nutrition JO - Public Health Nutr VL - 20 IS - 1 N2 - OBJECTIVE: To test the association between coffee consumption and risk of all-cause, CVD and cancer death in a European cohort. DESIGN: Prospective cohort study. Cox proportional hazards models with adjustment for potential confounders to estimate multivariable hazard ratios (HR) and 95 % CI were used. SETTING: Czech Republic, Russia and Poland. SUBJECTS: A total of 28561 individuals followed for 6·1 years. RESULTS: A total of 2121 deaths (43·1 % CVD and 35·7 % cancer mortality) occurred during the follow-up. Consumption of 3-4 cups coffee/d was associated with lower mortality risk in men (HR=0·83; 95 % CI 0·71, 0·99) and women (HR=0·63; 95 % CI 0·47, 0·84), while further intake showed non-significant reduced risk estimates (HR=0·71; 95 % CI 0·49, 1·04 and HR=0·51; 95 % CI 0·24, 1·10 in men and women, respectively). Decreased risk of CVD mortality was also found in men (HR=0·71; 95 % CI 0·54, 0·93) for consumption of 3-4 cups coffee/d. Stratified analysis revealed that consumption of a similar amount of coffee was associated with decreased risk of all-cause (HR=0·61; 95 % CI 0·43, 0·87) and cancer mortality (HR=0·59; 95 % CI 0·35, 0·99) in non-smoking women and decreased risk of all-cause mortality for >4 cups coffee/d in men with no/moderate alcohol intake. CONCLUSIONS: Coffee consumption was associated with decreased risk of mortality. The protective effect was even stronger when stratification by smoking status and alcohol intake was performed. SN - 1475-2727 UR - https://www.unboundmedicine.com/medline/citation/27411779/Coffee_consumption_and_mortality_in_three_Eastern_European_countries:_results_from_the_HAPIEE__Health_Alcohol_and_Psychosocial_factors_In_Eastern_Europe__study_ L2 - https://www.cambridge.org/core/product/identifier/S1368980016001749/type/journal_article DB - PRIME DP - Unbound Medicine ER -