Tags

Type your tag names separated by a space and hit enter

The Successful Treatment of Calciphylaxis with Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient with Chronic Kidney Disease.
Intern Med 2016; 55(14):1899-905IM

Abstract

We present the case of a non-dialyzed patient with chronic kidney disease and biopsy-proven calciphylaxis who presented with painful cutaneous ulcers on both legs. The skin ulcers drastically improved within 6 months after the initiation of hemodialysis, aggressive wound care, the control of a mineral and bone disorder, and the administration of sodium thiosulfate and hyperbaric oxygen therapy. Notably, the patient's serum levels of C-reactive protein and calciprotein particles decreased and her serum albumin and fetuin-A levels increased in parallel with the alleviation of her calciphylaxis. This case highlights the importance of applying combined medical treatment to calciphylaxis and suggests the possible involvement of calciprotein particles in the pathogenesis of calciphylaxis.

Authors+Show Affiliations

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27432100

Citation

Aihara, Seishi, et al. "The Successful Treatment of Calciphylaxis With Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient With Chronic Kidney Disease." Internal Medicine (Tokyo, Japan), vol. 55, no. 14, 2016, pp. 1899-905.
Aihara S, Yamada S, Uchida Y, et al. The Successful Treatment of Calciphylaxis with Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient with Chronic Kidney Disease. Intern Med. 2016;55(14):1899-905.
Aihara, S., Yamada, S., Uchida, Y., Arase, H., Tsuchimoto, A., Nakano, T., ... Tsuruya, K. (2016). The Successful Treatment of Calciphylaxis with Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient with Chronic Kidney Disease. Internal Medicine (Tokyo, Japan), 55(14), pp. 1899-905. doi:10.2169/internalmedicine.55.6326.
Aihara S, et al. The Successful Treatment of Calciphylaxis With Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient With Chronic Kidney Disease. Intern Med. 2016;55(14):1899-905. PubMed PMID: 27432100.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Successful Treatment of Calciphylaxis with Sodium Thiosulfate and Hyperbaric Oxygen in a Non-dialyzed Patient with Chronic Kidney Disease. AU - Aihara,Seishi, AU - Yamada,Shunsuke, AU - Uchida,Yushi, AU - Arase,Hokuto, AU - Tsuchimoto,Akihiro, AU - Nakano,Toshiaki, AU - Taniguchi,Masatomo, AU - Higashi,Harumichi, AU - Kitazono,Takanari, AU - Tsuruya,Kazuhiko, Y1 - 2016/07/15/ PY - 2016/7/20/entrez PY - 2016/7/20/pubmed PY - 2017/3/28/medline SP - 1899 EP - 905 JF - Internal medicine (Tokyo, Japan) JO - Intern. Med. VL - 55 IS - 14 N2 - We present the case of a non-dialyzed patient with chronic kidney disease and biopsy-proven calciphylaxis who presented with painful cutaneous ulcers on both legs. The skin ulcers drastically improved within 6 months after the initiation of hemodialysis, aggressive wound care, the control of a mineral and bone disorder, and the administration of sodium thiosulfate and hyperbaric oxygen therapy. Notably, the patient's serum levels of C-reactive protein and calciprotein particles decreased and her serum albumin and fetuin-A levels increased in parallel with the alleviation of her calciphylaxis. This case highlights the importance of applying combined medical treatment to calciphylaxis and suggests the possible involvement of calciprotein particles in the pathogenesis of calciphylaxis. SN - 1349-7235 UR - https://www.unboundmedicine.com/medline/citation/27432100/The_Successful_Treatment_of_Calciphylaxis_with_Sodium_Thiosulfate_and_Hyperbaric_Oxygen_in_a_Non_dialyzed_Patient_with_Chronic_Kidney_Disease_ L2 - https://dx.doi.org/10.2169/internalmedicine.55.6326 DB - PRIME DP - Unbound Medicine ER -