Molecularly imprinted polymers for dispersive solid-phase extraction of phenolic compounds in aqueous samples coupled with capillary electrophoresis.
Electrophoresis. 2016 10; 37(19):2487-2495.E

Abstract

A simple and sensitive method for the simultaneous determination of seven phenolic compounds in aqueous samples was developed by dispersive solid-phase extraction (DSPE) coupled with capillary electrophoresis (CE), namely phenol, 4-chlorophenol (4-CP), pentachlorophenol (PCP), 2,4,6-trichlorophenol (2,4,6-TCP), 2,4-dichlorophenol (2,4-DCP), 2-chlorophenol (2-CP) and 2,6-dichlorophenol (2,6-DCP). Molecularly imprinted polymers (MIPs) prepared by precipitation polymerization with 2,4,6-trichlorophenol (2,4,6-TCP) as template were used as DSPE sorbents to selectively adsorb the phenols. Various parameters affecting the extraction efficiency were evaluated and excellent CE separation was achieved within 13.5 min by using 15 mmol/L borate buffer containing 15% (v/v) methanol at pH = 9.8. Under the optimized conditions, good linearity was obtained in the range of 2-200 μg/L for phenol, 2,4-DCP and 2,6-DCP, 2-300 μg/L for 4-CP and 2-CP, 1.5-150 μg/L for PCP, and 2-400 μg/L for 2,4,6-TCP, with the correlation coefficient (R2) higher than 0.9938. Limits of detection and limits of quantification were in the range of 0.18-0.44 μg/L and 0.59-1.45 μg/L, respectively. The developed MIPs-DSPE-CE method was also successfully applied to determine the seven phenolic compounds in lake, tap, seawater and tannery wastewater. The average recoveries at three different spiked levels ranged from 70.75 to 106.7% with the relative standard deviations of 1.15-6.28%.

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Authors+Show Affiliations

Lu W

National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu, P. R. China. Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, P. R. China.

Ming W

Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, P. R. China.

Zhang X

National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu, P. R. China. zhangxinshen@126.com. State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University, Chengdu, P. R. China. zhangxinshen@126.com.

Chen L

Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, P. R. China.

MeSH

Electrophoresis, CapillaryLimit of DetectionLinear ModelsMolecular ImprintingPhenolsReproducibility of ResultsSolid Phase ExtractionWater Pollutants, Chemical

Pub Type(s)

Journal Article

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

27436547

Citation

Lu, Wenhui, et al. "Molecularly Imprinted Polymers for Dispersive Solid-phase Extraction of Phenolic Compounds in Aqueous Samples Coupled With Capillary Electrophoresis." Electrophoresis, vol. 37, no. 19, 2016, pp. 2487-2495.

Lu W, Ming W, Zhang X, et al. Molecularly imprinted polymers for dispersive solid-phase extraction of phenolic compounds in aqueous samples coupled with capillary electrophoresis. Electrophoresis. 2016;37(19):2487-2495.

Lu, W., Ming, W., Zhang, X., & Chen, L. (2016). Molecularly imprinted polymers for dispersive solid-phase extraction of phenolic compounds in aqueous samples coupled with capillary electrophoresis. Electrophoresis, 37(19), 2487-2495. https://doi.org/10.1002/elps.201600119

Lu W, et al. Molecularly Imprinted Polymers for Dispersive Solid-phase Extraction of Phenolic Compounds in Aqueous Samples Coupled With Capillary Electrophoresis. Electrophoresis. 2016;37(19):2487-2495. PubMed PMID: 27436547.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Molecularly imprinted polymers for dispersive solid-phase extraction of phenolic compounds in aqueous samples coupled with capillary electrophoresis. AU - Lu,Wenhui, AU - Ming,Weina, AU - Zhang,Xinshen, AU - Chen,Lingxin, Y1 - 2016/08/15/ PY - 2016/03/13/received PY - 2016/05/20/revised PY - 2016/07/13/accepted PY - 2016/7/21/pubmed PY - 2017/8/19/medline PY - 2016/7/21/entrez KW - Aqueous samples KW - Capillary electrophoresis KW - Dispersive solid-phase extraction KW - Molecularly imprinted polymers KW - Phenolic compounds SP - 2487 EP - 2495 JF - Electrophoresis JO - Electrophoresis VL - 37 IS - 19 N2 - A simple and sensitive method for the simultaneous determination of seven phenolic compounds in aqueous samples was developed by dispersive solid-phase extraction (DSPE) coupled with capillary electrophoresis (CE), namely phenol, 4-chlorophenol (4-CP), pentachlorophenol (PCP), 2,4,6-trichlorophenol (2,4,6-TCP), 2,4-dichlorophenol (2,4-DCP), 2-chlorophenol (2-CP) and 2,6-dichlorophenol (2,6-DCP). Molecularly imprinted polymers (MIPs) prepared by precipitation polymerization with 2,4,6-trichlorophenol (2,4,6-TCP) as template were used as DSPE sorbents to selectively adsorb the phenols. Various parameters affecting the extraction efficiency were evaluated and excellent CE separation was achieved within 13.5 min by using 15 mmol/L borate buffer containing 15% (v/v) methanol at pH = 9.8. Under the optimized conditions, good linearity was obtained in the range of 2-200 μg/L for phenol, 2,4-DCP and 2,6-DCP, 2-300 μg/L for 4-CP and 2-CP, 1.5-150 μg/L for PCP, and 2-400 μg/L for 2,4,6-TCP, with the correlation coefficient (R2) higher than 0.9938. Limits of detection and limits of quantification were in the range of 0.18-0.44 μg/L and 0.59-1.45 μg/L, respectively. The developed MIPs-DSPE-CE method was also successfully applied to determine the seven phenolic compounds in lake, tap, seawater and tannery wastewater. The average recoveries at three different spiked levels ranged from 70.75 to 106.7% with the relative standard deviations of 1.15-6.28%. SN - 1522-2683 UR - https://www.unboundmedicine.com/medline/citation/27436547/Molecularly_imprinted_polymers_for_dispersive_solid_phase_extraction_of_phenolic_compounds_in_aqueous_samples_coupled_with_capillary_electrophoresis_ DB - PRIME DP - Unbound Medicine ER -

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Molecularly imprinted polymers for dispersive solid-phase extraction of phenolic compounds in aqueous samples coupled with capillary electrophoresis.Electrophoresis. 2016 10; 37(19):2487-2495.E