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A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort.
Int J Cancer 2016; 139(10):2221-31IJ

Abstract

Marked racial differences exist in dietary patterns and obesity, as well as cancer mortality. This study aims to assess whether dietary patterns are associated with cancer mortality overall and by race. We identified 22,041 participants from the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. Dietary patterns were categorized into: Convenience (Chinese and Mexican foods, pasta, pizza), Plant-based (fruits, vegetables), Southern (added fats, fried foods, sugar-sweetened beverages), Sweets/Fats (sugary foods) and Alcohol/Salads (alcohol, green-leafy vegetables, salad dressing). Using Cox regression, we examined the association between quartiles of dietary patterns and cancer mortality, adjusted for potential confounders, overall among all participants and stratified by race. A total of 873 cancer deaths were observed over the 10-year observation period: 582 (66.7%) in Whites and 291 (33.3%) in Blacks. Greater adherence to the Southern dietary pattern was associated with an increased risk of cancer mortality (4th vs. 1st quartile HR: 1.67; 95% CI: 1.32-2.10) overall, especially among Whites (4th vs. 1st quartile HR: 1.59; 95% CI: 1.22-2.08). The convenience (HR: 0.73; 95% CI: 0.56-0.94) and Plant-based (HR: 0.72; 95% CI: 0.55-0.93) dietary patterns were associated with up to a 28% reduced risk of cancer mortality, but only among Whites. Greater adherence to the Southern dietary pattern increased the risk of cancer mortality, while greater adherence to the convenience and Plant-based diets reduced the risk of cancer mortality among Whites. Racial differences were observed in the association between dietary patterns and cancer mortality, but warrant further study.

Authors+Show Affiliations

Departments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL. tomiakin@uab.edu. Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL. tomiakin@uab.edu.Departments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL. Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL. Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL.Department of Clinical Cancer Prevention and Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX.Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL.Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA.Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

27459634

Citation

Akinyemiju, Tomi, et al. "A Prospective Study of Dietary Patterns and Cancer Mortality Among Blacks and Whites in the REGARDS Cohort." International Journal of Cancer, vol. 139, no. 10, 2016, pp. 2221-31.
Akinyemiju T, Moore JX, Pisu M, et al. A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort. Int J Cancer. 2016;139(10):2221-31.
Akinyemiju, T., Moore, J. X., Pisu, M., Lakoski, S. G., Shikany, J., Goodman, M., & Judd, S. E. (2016). A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort. International Journal of Cancer, 139(10), pp. 2221-31. doi:10.1002/ijc.30287.
Akinyemiju T, et al. A Prospective Study of Dietary Patterns and Cancer Mortality Among Blacks and Whites in the REGARDS Cohort. Int J Cancer. 2016 11 15;139(10):2221-31. PubMed PMID: 27459634.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort. AU - Akinyemiju,Tomi, AU - Moore,Justin Xavier, AU - Pisu,Maria, AU - Lakoski,Susan G, AU - Shikany,James, AU - Goodman,Michael, AU - Judd,Suzanne E, Y1 - 2016/08/09/ PY - 2016/05/11/received PY - 2016/06/12/revised PY - 2016/07/18/accepted PY - 2016/7/27/entrez PY - 2016/7/28/pubmed PY - 2017/4/25/medline KW - cancer KW - diet KW - mortality KW - prospective cohort KW - racial disparities SP - 2221 EP - 31 JF - International journal of cancer JO - Int. J. Cancer VL - 139 IS - 10 N2 - Marked racial differences exist in dietary patterns and obesity, as well as cancer mortality. This study aims to assess whether dietary patterns are associated with cancer mortality overall and by race. We identified 22,041 participants from the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. Dietary patterns were categorized into: Convenience (Chinese and Mexican foods, pasta, pizza), Plant-based (fruits, vegetables), Southern (added fats, fried foods, sugar-sweetened beverages), Sweets/Fats (sugary foods) and Alcohol/Salads (alcohol, green-leafy vegetables, salad dressing). Using Cox regression, we examined the association between quartiles of dietary patterns and cancer mortality, adjusted for potential confounders, overall among all participants and stratified by race. A total of 873 cancer deaths were observed over the 10-year observation period: 582 (66.7%) in Whites and 291 (33.3%) in Blacks. Greater adherence to the Southern dietary pattern was associated with an increased risk of cancer mortality (4th vs. 1st quartile HR: 1.67; 95% CI: 1.32-2.10) overall, especially among Whites (4th vs. 1st quartile HR: 1.59; 95% CI: 1.22-2.08). The convenience (HR: 0.73; 95% CI: 0.56-0.94) and Plant-based (HR: 0.72; 95% CI: 0.55-0.93) dietary patterns were associated with up to a 28% reduced risk of cancer mortality, but only among Whites. Greater adherence to the Southern dietary pattern increased the risk of cancer mortality, while greater adherence to the convenience and Plant-based diets reduced the risk of cancer mortality among Whites. Racial differences were observed in the association between dietary patterns and cancer mortality, but warrant further study. SN - 1097-0215 UR - https://www.unboundmedicine.com/medline/citation/27459634/A_prospective_study_of_dietary_patterns_and_cancer_mortality_among_Blacks_and_Whites_in_the_REGARDS_cohort_ L2 - https://doi.org/10.1002/ijc.30287 DB - PRIME DP - Unbound Medicine ER -