Tags

Type your tag names separated by a space and hit enter

Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team.
Gastrointest Endosc 2017; 85(4):816-821GE

Abstract

BACKGROUND AND AIMS

The Japan NBI Expert Team (JNET) was established in 2011 and has proposed a universal narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors. The aim of this study was to evaluate the clinical usefulness of the JNET classification for colorectal lesions.

METHODS

We analyzed 2933 colorectal lesions, which were diagnosed by NBI magnifying observation before endoscopic treatment or surgery. The colorectal lesions consisted of 136 hyperplastic polyps/sessile serrated polyps (HPs/SSPs), 1926 low-grade dysplasia (LGD), 571 high-grade dysplasia (HGD), 87 superficial submucosal invasive (SM-s) carcinomas, and 213 deep submucosal invasive (SM-d) carcinomas. We evaluated the relationship between the JNET classification and the histologic findings of these lesions.

RESULTS

The sensitivity, specificity, positive and negative predictive values, and accuracy of Type 1 lesions for the diagnosis of HP/SSP were, respectively, 87.5%, 99.9%, 97.5%, 99.4%, and 99.3%; of Type 2A lesions for the diagnosis of LGD were 74.3%, 92.7%, 98.3%, 38.7%, and 77.1%; of Type 2B lesions for the diagnosis of HGD/SM-s carcinoma were 61.9%, 82.8%, 50.9%, 88.2%, and 78.1%; for Type 3 lesions for the diagnosis of SM-d carcinoma were 55.4%, 99.8%, 95.2%, 96.6%, and 96.6%, respectively.

CONCLUSIONS

Types 1, 2A, and 3 of the JNET classification were very reliable indicators for HP/SSP, LGD, and SM-d carcinoma, respectively. However, the specificity and positive predictive value of Type 2B were relatively lower than those of others. Therefore, an additional examination such as pit pattern diagnosis using chromoagents is necessary for accurate diagnosis of Type 2B lesions.

Authors+Show Affiliations

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.Department of Anatomical Pathology, Hiroshima University Hospital, Hiroshima, Japan.Health Service Center, Hiroshima University Hospital, Hiroshima, Japan.Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27460392

Citation

Sumimoto, Kyoku, et al. "Clinical Impact and Characteristics of the Narrow-band Imaging Magnifying Endoscopic Classification of Colorectal Tumors Proposed By the Japan NBI Expert Team." Gastrointestinal Endoscopy, vol. 85, no. 4, 2017, pp. 816-821.
Sumimoto K, Tanaka S, Shigita K, et al. Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team. Gastrointest Endosc. 2017;85(4):816-821.
Sumimoto, K., Tanaka, S., Shigita, K., Hirano, D., Tamaru, Y., Ninomiya, Y., ... Chayama, K. (2017). Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team. Gastrointestinal Endoscopy, 85(4), pp. 816-821. doi:10.1016/j.gie.2016.07.035.
Sumimoto K, et al. Clinical Impact and Characteristics of the Narrow-band Imaging Magnifying Endoscopic Classification of Colorectal Tumors Proposed By the Japan NBI Expert Team. Gastrointest Endosc. 2017;85(4):816-821. PubMed PMID: 27460392.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team. AU - Sumimoto,Kyoku, AU - Tanaka,Shinji, AU - Shigita,Kenjiro, AU - Hirano,Daiki, AU - Tamaru,Yuzuru, AU - Ninomiya,Yuki, AU - Asayama,Naoki, AU - Hayashi,Nana, AU - Oka,Shiro, AU - Arihiro,Koji, AU - Yoshihara,Masaharu, AU - Chayama,Kazuaki, Y1 - 2016/07/25/ PY - 2016/02/01/received PY - 2016/07/03/accepted PY - 2016/7/28/pubmed PY - 2017/10/12/medline PY - 2016/7/28/entrez SP - 816 EP - 821 JF - Gastrointestinal endoscopy JO - Gastrointest. Endosc. VL - 85 IS - 4 N2 - BACKGROUND AND AIMS: The Japan NBI Expert Team (JNET) was established in 2011 and has proposed a universal narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors. The aim of this study was to evaluate the clinical usefulness of the JNET classification for colorectal lesions. METHODS: We analyzed 2933 colorectal lesions, which were diagnosed by NBI magnifying observation before endoscopic treatment or surgery. The colorectal lesions consisted of 136 hyperplastic polyps/sessile serrated polyps (HPs/SSPs), 1926 low-grade dysplasia (LGD), 571 high-grade dysplasia (HGD), 87 superficial submucosal invasive (SM-s) carcinomas, and 213 deep submucosal invasive (SM-d) carcinomas. We evaluated the relationship between the JNET classification and the histologic findings of these lesions. RESULTS: The sensitivity, specificity, positive and negative predictive values, and accuracy of Type 1 lesions for the diagnosis of HP/SSP were, respectively, 87.5%, 99.9%, 97.5%, 99.4%, and 99.3%; of Type 2A lesions for the diagnosis of LGD were 74.3%, 92.7%, 98.3%, 38.7%, and 77.1%; of Type 2B lesions for the diagnosis of HGD/SM-s carcinoma were 61.9%, 82.8%, 50.9%, 88.2%, and 78.1%; for Type 3 lesions for the diagnosis of SM-d carcinoma were 55.4%, 99.8%, 95.2%, 96.6%, and 96.6%, respectively. CONCLUSIONS: Types 1, 2A, and 3 of the JNET classification were very reliable indicators for HP/SSP, LGD, and SM-d carcinoma, respectively. However, the specificity and positive predictive value of Type 2B were relatively lower than those of others. Therefore, an additional examination such as pit pattern diagnosis using chromoagents is necessary for accurate diagnosis of Type 2B lesions. SN - 1097-6779 UR - https://www.unboundmedicine.com/medline/citation/27460392/Clinical_impact_and_characteristics_of_the_narrow_band_imaging_magnifying_endoscopic_classification_of_colorectal_tumors_proposed_by_the_Japan_NBI_Expert_Team_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0016-5107(16)30386-8 DB - PRIME DP - Unbound Medicine ER -