Abstract
PURPOSE
To estimate the etiology and features of the eyes with rubeosis iridis among Korean patients.
MATERIALS AND METHODS
This study is a retrospective review of 533 Korean patients with rubeosis iridis who visited an eye hospital in Seoul, Korea. We defined rubeosis iridis as visible blood vessels on the iris surface detected during a slit-lamp examination. All cases were reviewed for age at the time of diagnosis, medical history, the most likely cause of rubeosis iridis, visual acuity, and intraocular pressure.
RESULTS
The most commonly observed cause of rubeosis iridis was diabetic retinopathy (DR; n = 337, 63.2%), followed by retinal vein occlusion (RVO; n = 101, 18.9%), ocular ischemic syndrome (OIS; n = 24, 4.5%), retinal detachment (n = 17, 3.2%), and uveitis (n = 15, 2.8%). The cause was classified as miscellaneous in 18 cases (3.4%); in 21 eyes (3.9%), the cause was not clear. Age at the time of rubeosis iridis diagnosis was lower in patients with DR (56.5 years) than in those with RVO (61.0 years) and OIS (64.8 years; P < 0.01). Intraocular pressure of the eyes with DR (37.3 mmHg) and RVO (39.5 mmHg) was higher than that of the eyes with OIS (25.8 mmHg; P < 0.01).
CONCLUSION
In our population-based single center study, DR was the leading cause of rubeosis iridis followed by RVO and OIS among Korean patients. The clinical characteristics of the eyes with rubeosis iridis differed according to etiology. This finding may be useful when assessing eyes with rubeosis iridis.
TY - JOUR
T1 - Etiology and Features of Eyes with Rubeosis Iridis among Korean Patients: A Population-Based Single Center Study.
AU - Jeong,Yun Cheol,
AU - Hwang,Young Hoon,
Y1 - 2016/08/04/
PY - 2015/12/18/received
PY - 2016/07/24/accepted
PY - 2016/8/5/entrez
PY - 2016/8/5/pubmed
PY - 2017/8/24/medline
SP - e0160662
EP - e0160662
JF - PloS one
JO - PLoS One
VL - 11
IS - 8
N2 - PURPOSE: To estimate the etiology and features of the eyes with rubeosis iridis among Korean patients. MATERIALS AND METHODS: This study is a retrospective review of 533 Korean patients with rubeosis iridis who visited an eye hospital in Seoul, Korea. We defined rubeosis iridis as visible blood vessels on the iris surface detected during a slit-lamp examination. All cases were reviewed for age at the time of diagnosis, medical history, the most likely cause of rubeosis iridis, visual acuity, and intraocular pressure. RESULTS: The most commonly observed cause of rubeosis iridis was diabetic retinopathy (DR; n = 337, 63.2%), followed by retinal vein occlusion (RVO; n = 101, 18.9%), ocular ischemic syndrome (OIS; n = 24, 4.5%), retinal detachment (n = 17, 3.2%), and uveitis (n = 15, 2.8%). The cause was classified as miscellaneous in 18 cases (3.4%); in 21 eyes (3.9%), the cause was not clear. Age at the time of rubeosis iridis diagnosis was lower in patients with DR (56.5 years) than in those with RVO (61.0 years) and OIS (64.8 years; P < 0.01). Intraocular pressure of the eyes with DR (37.3 mmHg) and RVO (39.5 mmHg) was higher than that of the eyes with OIS (25.8 mmHg; P < 0.01). CONCLUSION: In our population-based single center study, DR was the leading cause of rubeosis iridis followed by RVO and OIS among Korean patients. The clinical characteristics of the eyes with rubeosis iridis differed according to etiology. This finding may be useful when assessing eyes with rubeosis iridis.
SN - 1932-6203
UR - https://www.unboundmedicine.com/medline/citation/27490797/Etiology_and_Features_of_Eyes_with_Rubeosis_Iridis_among_Korean_Patients:_A_Population_Based_Single_Center_Study_
DB - PRIME
DP - Unbound Medicine
ER -
