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The Effect of Alcohol on Gastrointestinal Motility.
Rev Recent Clin Trials. 2016; 11(3):191-5.RR

Abstract

The Gastrointestinal (GI) tract is one of the most affected systems by alcohol consumption. Alcohol can affect the esophagus in several ways: induces mucosal inflammation, increases the risk for Barrett esophagus and esophageal cancer, and also impairs the esophageal motility. Numerous studies have reported an increased prevalence of Gastroesophageal Reflux Disease (GERD) or erosive esophagitis in alcoholics. Some alcoholics exhibit an abnormality of esophageal motility known as a "nutcracker esophagus". Alcohol effect on gastric motility depends on the alcohol concentration. In general, beverages with high alcohol concentrations (i.e., above 15 percent) appear to inhibit gastric motility and low alcohol doses (wine and beer) accelerate gastric emptying. Also, acute administration of ethanol inhibits the gastric emptying, while chronic administration of a large dose of alcohol accelerates gastric motility. The effect of alcohol on small bowel motility differs according to the type of consumption (acute or chronic). Acute administration of alcohol has been found to inhibit small bowel transit and chronic administration of a large dose of alcohol accelerates small bowel transit. This article reviews some of the below findings.

Authors+Show Affiliations

No affiliation info availableNo affiliation info availableSecond Dept. of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy Cluj- Napoca, Romania.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27527893

Citation

Grad, Simona, et al. "The Effect of Alcohol On Gastrointestinal Motility." Reviews On Recent Clinical Trials, vol. 11, no. 3, 2016, pp. 191-5.
Grad S, Abenavoli L, Dumitrascu DL. The Effect of Alcohol on Gastrointestinal Motility. Rev Recent Clin Trials. 2016;11(3):191-5.
Grad, S., Abenavoli, L., & Dumitrascu, D. L. (2016). The Effect of Alcohol on Gastrointestinal Motility. Reviews On Recent Clinical Trials, 11(3), 191-5.
Grad S, Abenavoli L, Dumitrascu DL. The Effect of Alcohol On Gastrointestinal Motility. Rev Recent Clin Trials. 2016;11(3):191-5. PubMed PMID: 27527893.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Effect of Alcohol on Gastrointestinal Motility. AU - Grad,Simona, AU - Abenavoli,Ludovico, AU - Dumitrascu,Dan L, PY - 2015/11/09/received PY - 2016/02/25/revised PY - 2016/03/10/accepted PY - 2016/8/17/entrez PY - 2016/8/17/pubmed PY - 2018/1/11/medline SP - 191 EP - 5 JF - Reviews on recent clinical trials JO - Rev Recent Clin Trials VL - 11 IS - 3 N2 - The Gastrointestinal (GI) tract is one of the most affected systems by alcohol consumption. Alcohol can affect the esophagus in several ways: induces mucosal inflammation, increases the risk for Barrett esophagus and esophageal cancer, and also impairs the esophageal motility. Numerous studies have reported an increased prevalence of Gastroesophageal Reflux Disease (GERD) or erosive esophagitis in alcoholics. Some alcoholics exhibit an abnormality of esophageal motility known as a "nutcracker esophagus". Alcohol effect on gastric motility depends on the alcohol concentration. In general, beverages with high alcohol concentrations (i.e., above 15 percent) appear to inhibit gastric motility and low alcohol doses (wine and beer) accelerate gastric emptying. Also, acute administration of ethanol inhibits the gastric emptying, while chronic administration of a large dose of alcohol accelerates gastric motility. The effect of alcohol on small bowel motility differs according to the type of consumption (acute or chronic). Acute administration of alcohol has been found to inhibit small bowel transit and chronic administration of a large dose of alcohol accelerates small bowel transit. This article reviews some of the below findings. SN - 1876-1038 UR - https://www.unboundmedicine.com/medline/citation/27527893/The_Effect_of_Alcohol_on_Gastrointestinal_Motility_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1574-8871&volume=11&issue=3&spage=191&aulast=Grad DB - PRIME DP - Unbound Medicine ER -