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Composition of the Leaf Essential Oil of Phoebe formosana from Taiwan and its in vitro Cytotoxic, Antibacterial, and Antifungal Activities.
Nat Prod Commun. 2016 Jun; 11(6):845-8.NP

Abstract

The essential oil from the leaves of Phoebe formosana from Taiwan was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Seventy-one compounds were identified, representing 100% of the oil. The main components identified were a-humulene (16.8%), τ-cadinol (8.9%), α-pinene (8.4%), α-cadinol (8.1%), β-caryophyllene (8.0%), β-phellandrene (6.0%), and β-eudesmol (5.8%). The oil exhibited cytotoxic activity against human lung, liver and oral cancer cells. The active compounds were β-caryophyllene, α-humulene, τ-cadinol, β-eudesmol, and α-cadinol. The antibacterial activity of the oil was tested by the disc diffusion and micro-broth dilution methods against eight bacterial species. The oil exhibited moderate growth suppression against Gram-positive bacteria with inhibition zones of 28 to 36 mm, and MIC values of 250 to 375 μg/mL. The active antibacterial compounds were determined to be τ-cadinol, β-eudesmol, and α-cadinol. The leaf oil displayed excellent antifungal activity with the active compounds determined as α-cadinol, β-eudesmol, τ-cadinol, α-humulene, and β-caryophyllene.

Authors

Su YC
No affiliation info available
Ho CL
No affiliation info available

MeSH

Anti-Bacterial AgentsAntifungal AgentsBacteriaCell LineCell SurvivalFungiHumansLauraceaeMicrobial Sensitivity TestsOils, VolatilePlant ExtractsPlant LeavesTaiwan

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27534132

Citation

Su, Yu-Chang, and Chen-Lung Ho. "Composition of the Leaf Essential Oil of Phoebe Formosana From Taiwan and Its in Vitro Cytotoxic, Antibacterial, and Antifungal Activities." Natural Product Communications, vol. 11, no. 6, 2016, pp. 845-8.
Su YC, Ho CL. Composition of the Leaf Essential Oil of Phoebe formosana from Taiwan and its in vitro Cytotoxic, Antibacterial, and Antifungal Activities. Nat Prod Commun. 2016;11(6):845-8.
Su, Y. C., & Ho, C. L. (2016). Composition of the Leaf Essential Oil of Phoebe formosana from Taiwan and its in vitro Cytotoxic, Antibacterial, and Antifungal Activities. Natural Product Communications, 11(6), 845-8.
Su YC, Ho CL. Composition of the Leaf Essential Oil of Phoebe Formosana From Taiwan and Its in Vitro Cytotoxic, Antibacterial, and Antifungal Activities. Nat Prod Commun. 2016;11(6):845-8. PubMed PMID: 27534132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition of the Leaf Essential Oil of Phoebe formosana from Taiwan and its in vitro Cytotoxic, Antibacterial, and Antifungal Activities. AU - Su,Yu-Chang, AU - Ho,Chen-Lung, PY - 2016/8/19/entrez PY - 2016/8/19/pubmed PY - 2016/10/1/medline SP - 845 EP - 8 JF - Natural product communications JO - Nat Prod Commun VL - 11 IS - 6 N2 - The essential oil from the leaves of Phoebe formosana from Taiwan was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Seventy-one compounds were identified, representing 100% of the oil. The main components identified were a-humulene (16.8%), τ-cadinol (8.9%), α-pinene (8.4%), α-cadinol (8.1%), β-caryophyllene (8.0%), β-phellandrene (6.0%), and β-eudesmol (5.8%). The oil exhibited cytotoxic activity against human lung, liver and oral cancer cells. The active compounds were β-caryophyllene, α-humulene, τ-cadinol, β-eudesmol, and α-cadinol. The antibacterial activity of the oil was tested by the disc diffusion and micro-broth dilution methods against eight bacterial species. The oil exhibited moderate growth suppression against Gram-positive bacteria with inhibition zones of 28 to 36 mm, and MIC values of 250 to 375 μg/mL. The active antibacterial compounds were determined to be τ-cadinol, β-eudesmol, and α-cadinol. The leaf oil displayed excellent antifungal activity with the active compounds determined as α-cadinol, β-eudesmol, τ-cadinol, α-humulene, and β-caryophyllene. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/27534132/Composition_of_the_Leaf_Essential_Oil_of_Phoebe_formosana_from_Taiwan_and_its_in_vitro_Cytotoxic_Antibacterial_and_Antifungal_Activities_ DB - PRIME DP - Unbound Medicine ER -