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Recent advances in component resolved diagnosis in food allergy.
Allergol Int 2016; 65(4):378-387AI

Abstract

Due to the high prevalence of food allergic diseases globally there are increasing demands in clinical practice for managing IgE-mediated conditions. During the last decade, component resolved diagnostics has been introduced into the field of clinical allergology, providing information that cannot be obtained from extract-based tests. Component resolved data facilitate more precise diagnosis of allergic diseases and identify sensitizations attributable to cross-reactivity. Furthermore it assists risk assessment in clinical practice as sensitization to some allergenic molecules is related to persistence of clinical symptoms and systemic rather than local reactions. The information may also aid the clinician in prescription of oral immunotherapy (OIT) in patients with severe symptoms, and in giving advice on food allergen avoidance or on the need to perform food challenges. The use of allergen components is rapidly evolving and increases our possibility to treat food allergic patients with a more individual approach. Using molecular allergology, we can already now better diagnose, prognose and grade the food allergy. In summary, daily routine molecular allergy diagnostics offers a number of benefits that give us a higher diagnostic precision and allow for better management of the patient.

Authors+Show Affiliations

Department of Maternal and Child Health, Uppsala University, Uppsala, Sweden. Electronic address: magnus.borres@kbh.uu.se.Laboratory of Food Quality Design and Development, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.Department of Allergy, Clinical Research Center for Allergology and Rheumatology, Sagamihara National Hospital, Kanagawa, Japan.Department of Allergy, Clinical Research Center for Allergology and Rheumatology, Sagamihara National Hospital, Kanagawa, Japan.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27543004

Citation

Borres, Magnus P., et al. "Recent Advances in Component Resolved Diagnosis in Food Allergy." Allergology International : Official Journal of the Japanese Society of Allergology, vol. 65, no. 4, 2016, pp. 378-387.
Borres MP, Maruyama N, Sato S, et al. Recent advances in component resolved diagnosis in food allergy. Allergol Int. 2016;65(4):378-387.
Borres, M. P., Maruyama, N., Sato, S., & Ebisawa, M. (2016). Recent advances in component resolved diagnosis in food allergy. Allergology International : Official Journal of the Japanese Society of Allergology, 65(4), pp. 378-387. doi:10.1016/j.alit.2016.07.002.
Borres MP, et al. Recent Advances in Component Resolved Diagnosis in Food Allergy. Allergol Int. 2016;65(4):378-387. PubMed PMID: 27543004.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent advances in component resolved diagnosis in food allergy. AU - Borres,Magnus P, AU - Maruyama,Nobuyuki, AU - Sato,Sakura, AU - Ebisawa,Motohiro, Y1 - 2016/08/16/ PY - 2016/06/30/received PY - 2016/07/07/revised PY - 2016/07/07/accepted PY - 2016/8/21/pubmed PY - 2017/1/19/medline PY - 2016/8/21/entrez KW - Allergen components KW - Component resolved diagnosis KW - Diagnosis KW - Food allergen KW - Molecular allergology SP - 378 EP - 387 JF - Allergology international : official journal of the Japanese Society of Allergology JO - Allergol Int VL - 65 IS - 4 N2 - Due to the high prevalence of food allergic diseases globally there are increasing demands in clinical practice for managing IgE-mediated conditions. During the last decade, component resolved diagnostics has been introduced into the field of clinical allergology, providing information that cannot be obtained from extract-based tests. Component resolved data facilitate more precise diagnosis of allergic diseases and identify sensitizations attributable to cross-reactivity. Furthermore it assists risk assessment in clinical practice as sensitization to some allergenic molecules is related to persistence of clinical symptoms and systemic rather than local reactions. The information may also aid the clinician in prescription of oral immunotherapy (OIT) in patients with severe symptoms, and in giving advice on food allergen avoidance or on the need to perform food challenges. The use of allergen components is rapidly evolving and increases our possibility to treat food allergic patients with a more individual approach. Using molecular allergology, we can already now better diagnose, prognose and grade the food allergy. In summary, daily routine molecular allergy diagnostics offers a number of benefits that give us a higher diagnostic precision and allow for better management of the patient. SN - 1440-1592 UR - https://www.unboundmedicine.com/medline/citation/27543004/Recent_advances_in_component_resolved_diagnosis_in_food_allergy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1323-8930(16)30101-0 DB - PRIME DP - Unbound Medicine ER -