Tags

Type your tag names separated by a space and hit enter

Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study.
Sports Med. 2017 04; 47(4):769-780.SM

Abstract

BACKGROUND

The minimum intensity of physical activity (PA) that is associated with favourable body composition and cardiorespiratory fitness (CRF) remains unknown.

OBJECTIVE

To investigate cross-sectional associations of PA and sedentary time (ST) with body composition and CRF in mid-childhood.

METHODS

PA, ST, body composition and CRF were measured in a population-based sample of 410 children (aged 7.6 ± 0.4 years). Combined heart-rate and movement sensing provided estimates of PA energy expenditure (PAEE, kJ/kg/day) and time (min/day) at multiple fine-grained metabolic equivalent (MET) levels, which were also collapsed to ST and light PA (LPA), moderate PA (MPA) and vigorous PA (VPA). Fat mass index (FMI, kg/m2), trunk fat mass index (TFMI, kg/m2) and fat-free mass index (FFMI, kg/m2.5) were derived from dual-energy X-ray absorptiometry. Maximal workload from a cycle ergometer test provided a measure of CRF (W/kg FFM). Linear regression and isotemporal substitution models were used to investigate associations.

RESULTS

The cumulative time above 2 METs (221 J/min/kg) was inversely associated with FMI and TFMI in both sexes (p < 0.001) whereas time spent above 3 METs was positively associated with CRF (p ≤ 0.002); CRF increased and adiposity decreased dose-dependently with increasing MET levels. ST was positively associated with FMI and TFMI (p < 0.001) but there were inverse associations between all PA categories (including LPA) and adiposity (p ≤ 0.002); the magnitude of these associations depended on the activity being displaced in isotemporal substitution models but were consistently stronger for VPA. PAEE, MPA and to a greater extent VPA, were all positively related to CRF (p ≤ 0.001).

CONCLUSIONS

PA exceeding 2 METs is associated with lower adiposity in mid-childhood, whereas PA of 3 METs is required to benefit CRF. VPA was most beneficial for fitness and fatness, from a time-for-time perspective, but displacing any lower-for-higher intensity may be an important first-order public health strategy. Clinical trial registry number (website): NCT01803776 (https://clinicaltrials.gov/ct2/show/NCT01803776).

Authors+Show Affiliations

PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK. Bradford Institute for Health Research, Bradford NHS Foundation Trust, Bradford, UK.PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK.Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland. Institute of Dentistry, University of Eastern Finland, Kuopio, Finland.PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK.PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK. UKCRC Centre for Diet and Activity Research (CEDAR), University of Cambridge School of Clinical Medicine, Cambridge, UK.Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland. Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK. Department of Sport Medicine, Norwegian School of Sports Science, Oslo, Norway.PA Programme, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Box 285, Cambridge, CB2 0QQ, UK. soren.brage@mrc-epid.cam.ac.uk.Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland. Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland. Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27558140

Citation

Collings, Paul J., et al. "Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time With Body Composition and Cardiorespiratory Fitness in Mid-Childhood: the PANIC Study." Sports Medicine (Auckland, N.Z.), vol. 47, no. 4, 2017, pp. 769-780.
Collings PJ, Westgate K, Väistö J, et al. Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study. Sports Med. 2017;47(4):769-780.
Collings, P. J., Westgate, K., Väistö, J., Wijndaele, K., Atkin, A. J., Haapala, E. A., Lintu, N., Laitinen, T., Ekelund, U., Brage, S., & Lakka, T. A. (2017). Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study. Sports Medicine (Auckland, N.Z.), 47(4), 769-780. https://doi.org/10.1007/s40279-016-0606-x
Collings PJ, et al. Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time With Body Composition and Cardiorespiratory Fitness in Mid-Childhood: the PANIC Study. Sports Med. 2017;47(4):769-780. PubMed PMID: 27558140.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cross-Sectional Associations of Objectively-Measured Physical Activity and Sedentary Time with Body Composition and Cardiorespiratory Fitness in Mid-Childhood: The PANIC Study. AU - Collings,Paul J, AU - Westgate,Kate, AU - Väistö,Juuso, AU - Wijndaele,Katrien, AU - Atkin,Andrew J, AU - Haapala,Eero A, AU - Lintu,Niina, AU - Laitinen,Tomi, AU - Ekelund,Ulf, AU - Brage,Soren, AU - Lakka,Timo A, PY - 2016/8/26/pubmed PY - 2018/6/19/medline PY - 2016/8/26/entrez SP - 769 EP - 780 JF - Sports medicine (Auckland, N.Z.) JO - Sports Med VL - 47 IS - 4 N2 - BACKGROUND: The minimum intensity of physical activity (PA) that is associated with favourable body composition and cardiorespiratory fitness (CRF) remains unknown. OBJECTIVE: To investigate cross-sectional associations of PA and sedentary time (ST) with body composition and CRF in mid-childhood. METHODS: PA, ST, body composition and CRF were measured in a population-based sample of 410 children (aged 7.6 ± 0.4 years). Combined heart-rate and movement sensing provided estimates of PA energy expenditure (PAEE, kJ/kg/day) and time (min/day) at multiple fine-grained metabolic equivalent (MET) levels, which were also collapsed to ST and light PA (LPA), moderate PA (MPA) and vigorous PA (VPA). Fat mass index (FMI, kg/m2), trunk fat mass index (TFMI, kg/m2) and fat-free mass index (FFMI, kg/m2.5) were derived from dual-energy X-ray absorptiometry. Maximal workload from a cycle ergometer test provided a measure of CRF (W/kg FFM). Linear regression and isotemporal substitution models were used to investigate associations. RESULTS: The cumulative time above 2 METs (221 J/min/kg) was inversely associated with FMI and TFMI in both sexes (p < 0.001) whereas time spent above 3 METs was positively associated with CRF (p ≤ 0.002); CRF increased and adiposity decreased dose-dependently with increasing MET levels. ST was positively associated with FMI and TFMI (p < 0.001) but there were inverse associations between all PA categories (including LPA) and adiposity (p ≤ 0.002); the magnitude of these associations depended on the activity being displaced in isotemporal substitution models but were consistently stronger for VPA. PAEE, MPA and to a greater extent VPA, were all positively related to CRF (p ≤ 0.001). CONCLUSIONS: PA exceeding 2 METs is associated with lower adiposity in mid-childhood, whereas PA of 3 METs is required to benefit CRF. VPA was most beneficial for fitness and fatness, from a time-for-time perspective, but displacing any lower-for-higher intensity may be an important first-order public health strategy. Clinical trial registry number (website): NCT01803776 (https://clinicaltrials.gov/ct2/show/NCT01803776). SN - 1179-2035 UR - https://www.unboundmedicine.com/medline/citation/27558140/Cross_Sectional_Associations_of_Objectively_Measured_Physical_Activity_and_Sedentary_Time_with_Body_Composition_and_Cardiorespiratory_Fitness_in_Mid_Childhood:_The_PANIC_Study_ L2 - https://dx.doi.org/10.1007/s40279-016-0606-x DB - PRIME DP - Unbound Medicine ER -