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Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization.
Sci Rep. 2016 08 25; 6:31929.SR

Abstract

Molar incisor hypomineralization (MIH) is a developmental defect of dental enamel that shares features with hypomineralized second primary molars (HSPM). Prior to permanent tooth eruption, second primary molars could have predictive value for permanent molar and incisor hypomineralization. To assess this possible relationship, a cross-sectional study was conducted in a sample of 414 children aged 8 and 9 years from the INMA cohort in Valencia (Spain). A calibrated examiner (linear-weighted Kappa 0.83) performed the intraoral examinations at the University of Valencia between November 2013 and 2014, applying the diagnostic criteria for MIH and HSPM adopted by the European Academy of Paediatric Dentistry. 100 children (24.2%) presented MIH and 60 (14.5%) presented HSPM. Co-occurrence of the two defects was observed in 11.1% of the children examined. The positive predictive value was 76.7% (63.9-86.6) and the negative predictive value 84.7% (80.6-88.3). The positive likelihood ratio (S/1-E) was 10.3 (5.9-17.9) and the negative likelihood ratio (1-S/E) 0.57 (0.47-0.68). The odds ratio was 18.2 (9.39-35.48). It was concluded that while the presence of HSPM can be considered a predictor of MIH, indicating the need for monitoring and control, the absence of this defect in primary dentition does not rule out the appearance of MIH.

Authors+Show Affiliations

Departament d'Estomatologia, Facultad de Medicina i Odontologia, Universitat de València, Spain.Departament d'Estomatologia, Facultad de Medicina i Odontologia, Universitat de València, Spain.Departament d'Estomatologia, Facultad de Medicina i Odontologia, Universitat de València, Spain.Departament d'Estomatologia, Facultad de Medicina i Odontologia, Universitat de València, Spain.Departament d'Estomatologia, Facultad de Medicina i Odontologia, Universitat de València, Spain.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

27558479

Citation

Negre-Barber, A, et al. "Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization." Scientific Reports, vol. 6, 2016, p. 31929.
Negre-Barber A, Montiel-Company JM, Boronat-Catalá M, et al. Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization. Sci Rep. 2016;6:31929.
Negre-Barber, A., Montiel-Company, J. M., Boronat-Catalá, M., Catalá-Pizarro, M., & Almerich-Silla, J. M. (2016). Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization. Scientific Reports, 6, 31929. https://doi.org/10.1038/srep31929
Negre-Barber A, et al. Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization. Sci Rep. 2016 08 25;6:31929. PubMed PMID: 27558479.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization. AU - Negre-Barber,A, AU - Montiel-Company,J M, AU - Boronat-Catalá,M, AU - Catalá-Pizarro,M, AU - Almerich-Silla,J M, Y1 - 2016/08/25/ PY - 2016/05/24/received PY - 2016/07/29/accepted PY - 2016/8/26/entrez PY - 2016/8/26/pubmed PY - 2018/5/15/medline SP - 31929 EP - 31929 JF - Scientific reports JO - Sci Rep VL - 6 N2 - Molar incisor hypomineralization (MIH) is a developmental defect of dental enamel that shares features with hypomineralized second primary molars (HSPM). Prior to permanent tooth eruption, second primary molars could have predictive value for permanent molar and incisor hypomineralization. To assess this possible relationship, a cross-sectional study was conducted in a sample of 414 children aged 8 and 9 years from the INMA cohort in Valencia (Spain). A calibrated examiner (linear-weighted Kappa 0.83) performed the intraoral examinations at the University of Valencia between November 2013 and 2014, applying the diagnostic criteria for MIH and HSPM adopted by the European Academy of Paediatric Dentistry. 100 children (24.2%) presented MIH and 60 (14.5%) presented HSPM. Co-occurrence of the two defects was observed in 11.1% of the children examined. The positive predictive value was 76.7% (63.9-86.6) and the negative predictive value 84.7% (80.6-88.3). The positive likelihood ratio (S/1-E) was 10.3 (5.9-17.9) and the negative likelihood ratio (1-S/E) 0.57 (0.47-0.68). The odds ratio was 18.2 (9.39-35.48). It was concluded that while the presence of HSPM can be considered a predictor of MIH, indicating the need for monitoring and control, the absence of this defect in primary dentition does not rule out the appearance of MIH. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/27558479/Hypomineralized_Second_Primary_Molars_as_Predictor_of_Molar_Incisor_Hypomineralization_ L2 - https://doi.org/10.1038/srep31929 DB - PRIME DP - Unbound Medicine ER -