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Carotenoids as biomarkers of fruit and vegetable intake in men and women.
Br J Nutr. 2016 Oct; 116(7):1206-1215.BJ

Abstract

High fruit and vegetable (FAV) intake is associated with a lower prevalence of chronic diseases. Identifying the ideal number of FAV servings needed to reduce chronic disease risk is, however, difficult because of biases inherent to common self-report dietary assessment tools. The aim of our study was to examine the associations between daily FAV intake and plasma carotenoid concentrations in men and women enrolled in a series of fully controlled dietary interventions. We compiled and analysed data from a group of 155 men and 109 women who participated in six fully controlled dietary interventions and compared post-intervention fasting plasma carotenoid (α-carotene, β-carotene, β-cryptoxanthin, lutein, lycopene, zeaxanthin) concentrations with regard to the daily FAV servings consumed by the participants. We found that plasma β-cryptoxanthin, lutein and zeaxanthin concentrations were positively associated with daily FAV servings (P≤0·005). However, daily FAV intake was negatively associated with plasma α-carotene (P<0·0005) and lycopene (P<0·0001) concentrations, whereas no association was noted with plasma β-carotene. When men and women were analysed separately, we found that for any given number of FAV servings consumed women had higher circulating lutein concentrations compared with men (P<0·01). Significant sex×FAV (P<0·0001) and sex×dietary β-cryptoxanthin (P<0·0005) interactions were also noted favouring higher plasma β-cryptoxanthin concentrations in women than in men for a given FAV consumption. Results from these fully controlled dietary feeding studies indicate that plasma β-cryptoxanthin and lutein concentrations can be used as robust biomarkers of FAV consumption. They also suggest the existence of sex differences influencing circulating β-cryptoxanthin and lutein concentrations following FAV consumption.

Authors+Show Affiliations

1School of Nutrition,Université Laval,Québec,Canada,G1V 0A6.1School of Nutrition,Université Laval,Québec,Canada,G1V 0A6.1School of Nutrition,Université Laval,Québec,Canada,G1V 0A6.2Institute of Nutrition and Functional Foods,Université Laval,Québec,Canada,G1V 0A6.1School of Nutrition,Université Laval,Québec,Canada,G1V 0A6.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27572625

Citation

Couillard, Charles, et al. "Carotenoids as Biomarkers of Fruit and Vegetable Intake in Men and Women." The British Journal of Nutrition, vol. 116, no. 7, 2016, pp. 1206-1215.
Couillard C, Lemieux S, Vohl MC, et al. Carotenoids as biomarkers of fruit and vegetable intake in men and women. Br J Nutr. 2016;116(7):1206-1215.
Couillard, C., Lemieux, S., Vohl, M. C., Couture, P., & Lamarche, B. (2016). Carotenoids as biomarkers of fruit and vegetable intake in men and women. The British Journal of Nutrition, 116(7), 1206-1215.
Couillard C, et al. Carotenoids as Biomarkers of Fruit and Vegetable Intake in Men and Women. Br J Nutr. 2016;116(7):1206-1215. PubMed PMID: 27572625.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carotenoids as biomarkers of fruit and vegetable intake in men and women. AU - Couillard,Charles, AU - Lemieux,Simone, AU - Vohl,Marie-Claude, AU - Couture,Patrick, AU - Lamarche,Benoît, Y1 - 2016/08/30/ PY - 2016/8/31/pubmed PY - 2017/5/26/medline PY - 2016/8/31/entrez KW - FAV fruits and vegetables KW - Biomarkers KW - Carotenoids KW - Diet-controlled intervention studies KW - Fruit and vegetable intake KW - Sex differences SP - 1206 EP - 1215 JF - The British journal of nutrition JO - Br J Nutr VL - 116 IS - 7 N2 - High fruit and vegetable (FAV) intake is associated with a lower prevalence of chronic diseases. Identifying the ideal number of FAV servings needed to reduce chronic disease risk is, however, difficult because of biases inherent to common self-report dietary assessment tools. The aim of our study was to examine the associations between daily FAV intake and plasma carotenoid concentrations in men and women enrolled in a series of fully controlled dietary interventions. We compiled and analysed data from a group of 155 men and 109 women who participated in six fully controlled dietary interventions and compared post-intervention fasting plasma carotenoid (α-carotene, β-carotene, β-cryptoxanthin, lutein, lycopene, zeaxanthin) concentrations with regard to the daily FAV servings consumed by the participants. We found that plasma β-cryptoxanthin, lutein and zeaxanthin concentrations were positively associated with daily FAV servings (P≤0·005). However, daily FAV intake was negatively associated with plasma α-carotene (P<0·0005) and lycopene (P<0·0001) concentrations, whereas no association was noted with plasma β-carotene. When men and women were analysed separately, we found that for any given number of FAV servings consumed women had higher circulating lutein concentrations compared with men (P<0·01). Significant sex×FAV (P<0·0001) and sex×dietary β-cryptoxanthin (P<0·0005) interactions were also noted favouring higher plasma β-cryptoxanthin concentrations in women than in men for a given FAV consumption. Results from these fully controlled dietary feeding studies indicate that plasma β-cryptoxanthin and lutein concentrations can be used as robust biomarkers of FAV consumption. They also suggest the existence of sex differences influencing circulating β-cryptoxanthin and lutein concentrations following FAV consumption. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/27572625/Carotenoids_as_biomarkers_of_fruit_and_vegetable_intake_in_men_and_women_ L2 - https://www.cambridge.org/core/product/identifier/S0007114516003056/type/journal_article DB - PRIME DP - Unbound Medicine ER -