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Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan.
Med Mycol J. 2016; 57(3):E63-6.MM

Abstract

Topical or systemic antifungal therapy was administered to patients diagnosed with Malassezia folliculitis during the 5-year period between March 2007 and October 2013. The diagnosis of Malassezia folliculitis was established on the basis of characteristic clinical features and direct microscopic findings (10 or more yeast-like fungi per follicle). Treatment consisted of topical application of 2% ketoconazole cream or 100 mg oral itraconazole based on symptom severity and patients' preferences. Treatment was given until papules flattened, and flat papules were examined to determine whether the patient's clinical condition had "improved" and the treatment had been "effective". The subjects were 44 patients (35 men, 9 women), with a mean disease period of 25±15 days. In regard to the lesion site, the frontal portion of the chest was the most common, accounting for 60% of all patients. The mean period required for improvement was 27±16 days in 37 patients receiving the topical antifungal agent and 14±4 days in the 7 patients receiving the systemic antifungal agent. The results were "improved" and the treatment was "effective" in all patients. Neither treatment resulted in any adverse reactions. Although administration of oral agents has been recommended for the treatment of Malassezia folliculitis, this study revealed that beneficial results are safely obtained with topical antifungal therapy alone, similar to those of systemic antifungal agents.

Authors+Show Affiliations

Department of Dermatology, Teikyo University Hospital.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27581777

Citation

Suzuki, Chikako, et al. "Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan." Medical Mycology Journal, vol. 57, no. 3, 2016, pp. E63-6.
Suzuki C, Hase M, Shimoyama H, et al. Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan. Med Mycol J. 2016;57(3):E63-6.
Suzuki, C., Hase, M., Shimoyama, H., & Sei, Y. (2016). Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan. Medical Mycology Journal, 57(3), E63-6. https://doi.org/10.3314/mmj.16-00003
Suzuki C, et al. Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan. Med Mycol J. 2016;57(3):E63-6. PubMed PMID: 27581777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment Outcomes for Malassezia Folliculitis in theDermatology Department of a University Hospital in Japan. AU - Suzuki,Chikako, AU - Hase,Midori, AU - Shimoyama,Harunari, AU - Sei,Yoshihiro, PY - 2016/9/2/entrez PY - 2016/9/2/pubmed PY - 2017/6/9/medline SP - E63 EP - 6 JF - Medical mycology journal JO - Med Mycol J VL - 57 IS - 3 N2 - Topical or systemic antifungal therapy was administered to patients diagnosed with Malassezia folliculitis during the 5-year period between March 2007 and October 2013. The diagnosis of Malassezia folliculitis was established on the basis of characteristic clinical features and direct microscopic findings (10 or more yeast-like fungi per follicle). Treatment consisted of topical application of 2% ketoconazole cream or 100 mg oral itraconazole based on symptom severity and patients' preferences. Treatment was given until papules flattened, and flat papules were examined to determine whether the patient's clinical condition had "improved" and the treatment had been "effective". The subjects were 44 patients (35 men, 9 women), with a mean disease period of 25±15 days. In regard to the lesion site, the frontal portion of the chest was the most common, accounting for 60% of all patients. The mean period required for improvement was 27±16 days in 37 patients receiving the topical antifungal agent and 14±4 days in the 7 patients receiving the systemic antifungal agent. The results were "improved" and the treatment was "effective" in all patients. Neither treatment resulted in any adverse reactions. Although administration of oral agents has been recommended for the treatment of Malassezia folliculitis, this study revealed that beneficial results are safely obtained with topical antifungal therapy alone, similar to those of systemic antifungal agents. SN - 1882-0476 UR - https://www.unboundmedicine.com/medline/citation/27581777/Treatment_Outcomes_for_Malassezia_Folliculitis_in_theDermatology_Department_of_a_University_Hospital_in_Japan_ L2 - https://dx.doi.org/10.3314/mmj.16-00003 DB - PRIME DP - Unbound Medicine ER -